A thermodynamic model of the quark-gluon plasma using quasiparticle degrees of freedom based on the hard thermal loop self-energies is introduced. It provides a connection between an established phenomenological quasiparticle model – following from the former using a series of approximations – and QCD – from which the former is derived using the Cornwall-Jackiw-Tomboulis formalism and a special parametrization of the running coupling. Both models allow for an extrapolation of first-principle QCD results available at small chemical potentials using Monte-Carlo methods on the lattice to large net baryon densities with remarkably similar results. They are used to construct equations of state for heavy-ion collider experiments at SPS and FAIR as well as quark and neutron star interiors. A mixed-phase construction allows for a connection of the SPS equation of state to the hadron resonance gas. An extension to the weak sector is presented as well as general stability and binding arguments for compact stellar objects are developed. From the extrapolation of the most recent lattice results [Baz09, Bor10b] the existence of bound pure quark stars is not suggested. However, quark matter might exist in a hybrid phase in cores of neutron stars.