Thesis (M.App.Sc. (Physio))--University of South Australia, 1998.

Thesis (MAppSci (Manipulative Therapy)) --University of South Australia, 1992

No description available.

L'analyse de la posture constitue un élément fondamental dans l'évaluation diagnostique et thérapeutique des patients atteints de déformations rachidiennes. Classiquement basée en pratique courante sur des radiographies du rachis en totalité, de nombreux paramètres posturaux ont été décrits et corrélés à la qualité de vie des patients. Toutefois, l'analyse radiographique conventionnelle ne permet pas systématiquement d'appréhender la posture véritable d'un individu. Une approche biomécanique de la posture en laboratoire d'analyse du mouvement permet donc de s'affranchir de ces contraintes et de caractériser la posture à l'aide de nouveaux paramètres. Un protocole spécifique biomécanique d'analyse de la posture, utilisant des plateformes de force et un système optoélectronique, a été développé afin de caractériser la posture libre d'un individu. D'autre part, ce protocole d'analyse peut ensuite être adapté à la pratique clinique quotidienne en couplant les données issues de la radiographie à celles d'une plateforme de pression. L'analyse d'une cohorte de volontaires sains a ainsi été réalisée, confirmant la faisabilité technique du calcul des moments nets inter segmentaires à l'aide de radiographies et d'une plateforme de pression. Les résultats de ce travail mettent en évidence la faisabilité et la fiabilité du protocole de mesure des moments inter-segmentaires. Ces résultats ouvrent des perspectives en pratique clinique courante avec la possibilité de réaliser cette analyse en pré et postopératoire a des fins diagnostics mais également pour évaluerl'influence du traitement chirurgical sur la modification des contraintes exercées sur le rachis. / Postural analysis is of primary importance for clinical and therapeutic evaluation of spinal deformity patients. This evaluation is currently based on full-spine radiographs and various parameters have been described and correlated with health related quality of life scores. However, this radiographic analysis is not applicable to every patient and can be sometimes misleading for physicians. A biomechanical postural approach using gait analysis is therefore necessary in order to avoid limits from the radiographic analysis. It provides new parameters for postural evaluation. A dedicated biomechanical "free-posture" protocol has been developed using force plates and gait analysis markers. Results from this approach revealed the reliability of the inter-segmental moment's measurements. Evolution of postural parameters during growth according to age was also described using a pediatric cohort. Concurrently, this biomechanical protocol can also be adapted to daily clinical practice, by the combination of a pressure platform and full-spine x-rays. Reliability of this combination was reported on a cohort of volunteers on whom spinal constraints were measured. These results are a source for potential new methods of postural outcomes evaluation in daily practice as they can be calculated during preoperative and postoperative courses.

Magister Chirurgiae Dentium - MChD / Aim: The aim of the study was to investigate whether a correlation exists between the intra- operative position of the Inferior Alveolar Nerve (IAN) and the nerve position as noted on a pre-operative Cone Beam Computer Tomography (CBCT) scan in patients requiring Bilateral Sagittal Split Osteotomy (BSSO) of the mandible. Introduction: The BSSO of the mandible is of fundamental importance in the correction of dental facial deformities. The main post-operative complication of a BSSO of the mandible is Neurosensory Impairment (NSI). To avoid possible NSI it is important to have as much pre- operative information as possible. In this regard, pre-operative CBCT scans can provide the surgeon with an important assessment of the mandibular canal. This information on the buccolingual, superior and inferior position of the canal, especially in the region of the planned osteotomy, could help the surgical team to avoid IAN injury. Materials and Methods: This study correlates the pre-operative position of the IAN as indicated on a CBCT scan with the intra-operative IAN position in patients requiring BSSO of the mandible. Ten standardised cases were included in a prospective case series where twenty mandibular sides were assessed. Results: The variables assessed in this study were location of the nerve, age, sex, type of movement and side of mandible operated on. It was found that only the distance between the Inferior Alveolar Canal (IAC) and the lower border of the mandible are predictive of whether the IAN will be attached to - or free from - the proximal segment of the mandible. Conclusion: From the study it can be concluded that a CBCT scan is a useful and reliable modality in the pre-operative evaluation of patients undergoing BSSO especially with regard to the assessment and mapping of the mandibular canal.

The primary objective of this study was to evaluate the relationship between milk-fat intake and obesity, particularly abdominal obesity, in 13,544 U.S. adults. A secondary objective was to determine the extent to which the association was influenced by multiple potential confounding variables. This cross-sectional study used data from the 2011–2016 National Health and Nutrition Examination Survey (NHANES). Level of milk-fat content regularly consumed was the exposure variable. Body mass index (BMI) and sagittal abdominal diameter (SAD), a measure of abdominal obesity, were the outcome variables. SAD correlates strongly with visceral fat, when measured by computed tomography, and has been shown to predict cardiometabolic disorders better than BMI. After controlling for age, gender, race, physical activity, sedentary behavior, alcohol habits, and cigarette use, significantly lower BMIs were associated with regular nonfat and full-fat milk consumption (F = 4.1, P = 0.0063). A significantly lower SAD was associated only with regular consumption of nonfat milk (F = 5.0, P = 0.0019). No significant differences were found between the other milk-fat groups or milk abstainers. In this nationally representative sample, only 19.6% of adults regularly consumed low-fat milk. In conclusion, regular nonfat milk intake was associated with lower levels of abdominal adiposity compared to consumption of higher levels of milk-fat.

Chest radiography is one of the most commonly performed radiographic examinations worldwide. Routinely acquired in the erect posteroanterior (PA) position, a chest radiograph displays substantial amounts of medical information when accurate patient positioning is achieved. However, a rotated PA chest radiograph has reduced diagnostic quality and appearances may mask or mimic chest pathology. Radiographic assessment of patient rotation around the sagittal plane has traditionally been undertaken by assessing the distance between the medial end of the clavicles and a line drawn through the spinous processes at the level of the clavicles. This approach continues to be advocated in radiographic technique textbooks internationally although no identified author has provided criteria to determine when a rotated PA chest radiograph should be repeated; determined the relationship between perceived clavicle to spinous process distance and actual degree of patient rotation; or considered the impact of body morphology, in particular the anteroposterior thoracic diameter, on radiographic appearances of rotation. Objectives To determine the impact of anteroposterior chest diameter on radiographic appearances of sagittal rotation on PA chest radiographs. Design Experimental study. Methods and Settings Sixty computed tomography thorax examinations, stratified for gender, were reviewed and data aggregated to determine average anteroposterior (AP) thoracic dimensions. A bespoke experimental unit was constructed specifically to enable testing of the impact of sagittal rotation on radiographic appearances. The experimental unit was situated within a calibrated circular frame enabling 360° rotation at 1° intervals around a central rotational point. The experimental unit components were varied in 1 cm intervals from 9 cm to 15 cm around the central rotation point to reflect varying AP chest diameters. At each interval, images were acquired at 0, 2, 5, 7, 10, and 15° sagittal rotation using a horizontal central ray, consistent centring point, and a source-image distance of 180 cm. Results A clear linear relationship between AP thoracic diameter and the radiographic appearances of sagittal rotation was noted. Considering significant rotation to be when the medial end of clavicle overlaps the spinous process on the radiographic image, this appearance occurred at a much smaller degree of rotation on wide AP thoracic diameters (15 cm, 5°) than narrower AP thoracic diameters (9 cm, 10°). Conclusions The routine application of the distance between the medial end of the clavicles and a line drawn through the spinous processes at the level of the clavicles as a method of assessing degree of sagittal rotation, diagnostic image quality, and need for repeat is flawed. Persistence in the application of this approach without cognisance of the impact of body morphology on radiographic appearances will result in persons with large AP thoracic diameters being more likely to have a PA chest radiograph repeated for a specified degree of rotation than persons with smaller AP thoracic diameters. / © 2015 Elsevier. Reproduced in accordance with the publisher's self-archiving policy.

Introduktion: Avsikten med denna studie var att undersöka och beskriva de olika komplikationer som kan uppkomma vid och efter en bilateral sagittal split osteotomi samt fastställa deras incidens och påverkan på slutresultatet.Metod: Vi har använt oss av 4 läroböcker för att få förståelse för tillvägagångssättet vid en BSSO. Vår artikelsökning gav totalt 49 artiklar som vi läste i sin helhet genom inklusions- och exklusionskriterier. Vi valde sedan ut 34 artiklar av dessa som vi sedan använde oss av i arbetet gällande komplikationer vid BSSO.Resultat: Direkt postoperativt hade skador på nervus alverolaris inferior högsta incidens (91%) av komplikationerna. Incidens av skador på nervus lingualis var 19,4%, bad splits 6,49%, blödning 1,2%, nervskador på nervus facialis 0,67% samt non-union 0,47%. Av de komplikationer, som sågs 1 år postoperativt, hade recidiv vid posterior flyttning högst incidens på 28% och recidiv vid anterior flyttning 21%. Vid skador på n. lingualis låg incidensen 13,44%, skador på n. alveolaris inferior 10,75% och tempromandibulära dysfunktioner 3,7%.Slutsats: Permanenta komplikationer vid BSSO sker sällan och de komplikationer som uppkommer kan oftast lösas med reoperation. Skador på n alveolaris inferior har högst incidens vid BSSO. Detta är en komplikation som dock inte går att korrigera i efterhand och som kan påverka patienten under en längre tid. Därför bör patienten preoperativt vara informerad om de olika komplikationer som kan uppkomma.

La scoliose de l’adulte est une pathologie dont la prévalence augmente avec de le vieillissement de la population. De plus, la demande fonctionnelle est de plus en plus importante chez ces patients. De nombreuses études ont montré un bénéfice du traitement chirurgical de la déformation de l’adulte par rapport au traitement médical en termes d’amélioration des scores fonctionnels, de qualité de vie et de satisfaction. Néanmoins, cette chirurgie est associée à de nombreuses complications (jusque 50% dans certaines séries), pour la plupart mécaniques telle la pseudarthrose, la rupture d’implant, la dégradation des étages adjacents. Ainsi, si l’analyse radiographique de la scoliose a bien été explorée, certaines questions demeurent comme les phénomènes responsables d’une aggravation brutale de la déformation chez certains patients ou les causes d’échecs. L’objectif de ce travail était d’analyser la scoliose de l’adulte, en 3D à l’aide de la stéréoradiographie et d’évaluer le système musculaire de ces patients afin de mettre en évidence des relations entre déformations rachidiennes notamment par l’analyse du plan horizontal, et dégénérescence musculaire.La 1e partie de ce travail était consacrée à l’analyse 3D de la scoliose : tout d’abord avec l’analyse de reproductibilité chez l’adulte des mesures 3D effectuées par stéréoradiographie, puis par l’analyse de l’alignement global de ces patients avec une déformation rachidienne, à l’aide d’un nouveau paramètre prenant en compte la position de la jonction cervico-céphalique. Apres avoir analysé l’alignement postural, le système musculaire pelvi-rachidien a été étudié dans la 2e partie. En effet, en plus de l’alignement du squelette, c’est l’activation du système musculaire qui est responsable du maintien d’une posture érigée. Nous avons décrit les caractéristiques musculaires des patients avec une scoliose lombaire et analysé les relations avec les paramètres radiographiques de la déformation, montrant que selon le type de déformation certains groupes musculaires étaient plus touchés par l’atrophie et l’infiltration graisseuse. En les comparant à des sujets jeunes et âgés sans déformation, nous avons observé que les patients avec une scoliose avaient une dégénérescence musculaire à la fois liée à la déformation et au vieillissement. Dans une 3e partie, en faisant le lien entre les données de la posture par la stéréoradiographie et les données musculaires de l’IRM, nous avons utilisé un modèle musculosquelettique personnalisé pour mieux comprendre les contraintes exercées sur les segments vertébraux et donc pour essayer d’expliquer les faillites mécaniques.Ainsi, l’association de mesures 3D radiographiques et de l’analyse musculaire pourrait permettre en comprenant mieux les phénomènes dégénératifs, de mieux prédire l’aggravation de la déformation et donc de la prévenir par une rééducation ciblée. Par exemple, un renforcement des érecteurs du rachis mais aussi des fléchisseurs pourrait permettre de mieux maintenir la posture. Et, un renforcement des érecteurs et fléchisseurs de hanche pourrait permettre d’activer de manière plus efficace, les mécanismes de compensation telle la rétroversion pelvienne. De plus, la mise en évidence de facteur de risque musculosquelettique d’aggravation de la déformation entrainerait une prise en charge plus précoce de ces patients. Une analyse longitudinale serait donc intéressante. / Adult degenerative scoliosis is a pathology whose prevalence increases with the aging of the population. Moreover, the functional demand is more and more important in these patients. Many studies have shown a benefit of surgical treatment of adult spinal deformity compared to medical treatment in terms of improved functional scores, quality of life and satisfaction. Nevertheless, this surgery is associated with many complications (up to 50% in some series), mostly mechanical such as nonunion, implant rupture, degradation of adjacent levels. Thus, if the radiographic analysis of scoliosis has been well explored, some questions remain like the phenomena responsible for a sudden worsening of the deformation in certain patients or the causes of failures. The aim of this work was to analyze adult scoliosis in 3D using stereoradiography and to evaluate the muscular system of these patients in order to highlight the relationships between spinal deformities, particularly by the horizontal plane analysis, and muscle degeneration.The first part of this work was dedicated to the 3D analysis of scoliosis: first, with the analysis of reproducibility in the adult of 3D stereoradiographic measurements, then by the analysis of the global alignment of these patients with spinal deformity, using a new parameter taking into account the position of the cervico-cephalic junction. After analyzing the postural alignment, the spino-pelvic muscular system was studied in the second part. Indeed, in addition to the alignment of the skeleton, it is the activation of the muscular system that is responsible for maintaining an erect posture. We described the muscular features of patients with lumbar scoliosis and analyzed the relationships with the radiographic parameters of the deformity, showing that depending on the type of deformity some muscle groups were more affected by atrophy and fatty infiltration. Comparing them to young and elderly subjects without deformity, we observed that patients with scoliosis had muscle degeneration that was both related to deformity and aging. In the third part, by linking stereoradiographic posture data with muscular MRI data, we used a personalized musculoskeletal model to better understand the constraints on vertebral segments and therefore to try to explain the mechanical failures.Thus, the combination of 3D radiographic measurements and muscle analysis could better predict muscle degeneration and worsening of deformity and thus prevent it by targeted rehabilitation. For example, a strengthening of the erectors of the spine but also of the flexors could allow better maintaining the posture. And, a strengthening of the erectors and hip flexors could allow activating more effectively, compensation mechanisms such pelvic retroversion. In addition, the demonstration of a musculoskeletal risk factor worsening the deformity would lead to an earlier management of these patients. A longitudinal analysis would be interesting.

Les déformations rachidiennes se réfèrent aux patients avec une courbure anormal de la colonne vertébrale qui ont terminé leur croissance. Par leur prévalence, leur impact clinique, et le taux relativement élevé d'échecs chirurgicaux, elles représentent un défi thérapeutique. La recherche a permis de démontrer que la préservation ou la restauration de l'alignement, sont des éléments clé du traitement chirurgical. L'objectif de cette thèse était d'analyser le traitement des patients avec DR, avec un intérêt particulier pour la restauration de l'alignement sagittal et l'évaluation musculaire. Fondé sur une analyse rétrospective d'une base de données multicentriques, les deux premiers articles présentent une évaluation du traitement chirurgical en termes d'efficacité clinique et de réalignement radiographique. Les écarts entre la planification préopératoire et l'exécution opérationnelle ont aussi été étudiés avec une collecte de données prospectives, et ont mis en évidence la nécessité de mieux comprendre le rôle des muscles dans le maintien de la posture. Par conséquent, deux protocoles pour la caractérisation des principaux muscles impliqués dans l'alignement sagittal ont été validés. Les deux méthodes sont basées sur la segmentation manuelle d'acquisition IRM spécifique (méthode de Dixon) afin d'obtenir l'infiltration graisseuse en plus du volume musculaire. Une des méthodes permet d'obtenir la reconstruction 3D des muscles et donc de générer des modèles musculo-squelettiques personnalisés. L'autre ouvre la voie à une pratique clinique car nécessite seulement la segmentation de quatre coupes pour obtenir une évaluation des principaux groupes musculaires. Enfin, à partir de la première méthode, le système musculaire de patients avec DR a été décrit. / Adult spinal deformity(ASD) refers to abnormal curvatures of the spine in patients who have completed their growth. Due to its prevalence, clinical impact, and the relatively high rate of surgical failures, they represent a therapeutic challenge. Research has been able to demonstrate that the preservation or the restoration of the sagittal alignment, are key objectives of surgical treatment. The objective of this thesis is to analyze the treatment of ASD patients, with particular interest in restoration of sagittal alignment and to develop tools to assess the spino-pelvic musculature of ASD patients. Based on an analysis of a multicenter database, the first two articles present an evaluation of the surgical treatment in term of clinical effectiveness and radiographic realignment. In addition, the discrepancies between surgical preoperative planning and operative execution have been studied with a prospective data collection, and have highlighted the necessity to understand better the role of the muscles in the maintaining of the posture. Therefore two methods for the characterization of the muscles involved in the sagittal alignment have been validated. Both methods are based on manual segmentation of specific MRI acquisition (Dixon methods) in order to obtain precise fat infiltration quantification in addition to muscular volume. One method permits to obtain 3D reconstruction able to generate patient–specific musculoskeletal model. The other one open the path to a clinical purpose, because necessitate only segmentation of four slices to obtain an relevant evaluation of the muscular system. Finally, thanks to the first protocol the muscular system of ASD patients have been described.