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This survey research systematically collects Information on the long term effects of Irlen tinted lenses, from a specific diagnosed scotopic sensitive population. The survey used is based on Whiting's survey (1988), with variations and extensions made to increase information attained. Although the main focus of the survey is reading and related academic skills, other areas presenting new directions for further research, have also been included. 306 diagnosed scotopic sensitive Individuals, who had been using prescribed Irlen tinted lenses for a minimum of six months, were surveyed. 82.8 percent of the respondents indicated that they (or their child) had experienced great benefits from wearing Irlen tinted lenses. 70.1 percent Indicated that the greatest benefit had been in the area of reading. Cross-tabulations were made with length of time wearing the lenses, gender, and whether the respondent was filling in the questionnaire for themselves or for their child. The results of this descriptive research support Whiting's (1988), earlier findings. A review of the available literature and the Implications of these findings are discussed.

<p>As real time visualizations become more realistic it also becomes more important to simulate the perceptual effects of the human visual system. Such effects include the response to varying illumination, glare and differences between photopic and scotopic vision. This thesis evaluates several different tone mapping methods to allow a greater dynamic range to be used in real time visualisations. Several tone mapping methods have been implemented in the Avalanche Game Engine and evaluated using a small test group. To increase immersion in the visualization several filters aimed to simulate perceptual effects has also been implemented. The primary goal of these filters is to simulate scotopic vision. The tests showed that two tone mapping methods would be suitable for the environment used in the tests. The S-curve tone mapping method gave the best result while the Mean Value method gave good results while being the simplest to implement and the cheapest. The test subjects agreed that the simulation of scotopic vision enhanced the immersion in a visualization. The primary difficulties in this work has been lack of dynamic range in the input images and the challenges in coding real time graphics using a graphics processing unit.</p>

The first chapter explains the motivation for measuring rod function, in particular the rod’s dynamic recovery from a substantial bleach which results in so-called ‘rate limited’ recovery of sensitivity. The physiological processes that underpin the replenishment of the rod photopigment are described and discussed, and explain the way in which rod function can act as a marker for retinal health. Overall, this chapter explains why rod function is worthy of further investigation.Then follows a description of the experimental methods used in the study of rod function, presented in later chapters. The psychophysical procedures are described and a new method of dark adaptation measurement is presented. The key feature of this technique is a red background.Nonlinear mathematical models are used to describe the reduction in visual thresholds with time following a bleach. Chapter three describes the difficulties associated with numerical methods of nonlinear regression and presents a novel, multi start algorithm that extracts the parameters of interest from a model that adequately describes dark adaptation in the healthy normal subject.Chapter 4 verifies the algorithm presented in chapter 3, which is shown to be reliable and robust. A series of numerical experiments are performed to evaluate some of the characteristics of the algorithm’s performance.In chapter five, a series of experiments are presented to investigate the possible effect of a luminous background on dark adaptation (DA). The first experiment tests whether the rod system can detect a dim red background and the second, whether the rod thresh olds, when measured against light emitted by a red light emitting diode (LED), were linear. The third explores whether the background had any effect on the recovery of rod sensitivity. Finally, conventional contrast sensitivity is used to investigate the recovery from a photo bleach.A novel laboratory based apparatus was used to measure dark adaptation in a group of 36 subjects and the results of these measurements are presented in chapter six. The aim here was to see if the data collected were comparable with the dark adaptation data in the literature. These subjects were asked to make two visits so that an assessment of the test retest reliability of the method could be made. The method is shown to be reliable and capable of characterising the recovery of the visual system after a photo bleach.Although inherently flexible the analogue apparatus was prone to subject driven variability. Greater consistency of measurement was achieved using a digital device developed in partnership with an industry partner, Elektron (UK). This device, described in chapter seven provided fine control of many of the experimental parameters. It was used to measure the dark adaptation of a young healthy group of 21 people.This study uses new methodological approaches, both experimental and statistical, that are robust and reliable to facilitate investigation of rod function, and presents new findings about the early phase of rod sensitivity recovery.

Master of Science / Department of Architectural Engineering and Construction Science / Raphael A. Yunk / Sustainable design and green engineering practices have become a priority in the architectural design industry over the past few years. Energy codes and standards have become more stringent as energy costs rise and buildings become larger, consuming more energy and having a larger impact on the environment. One major area for improvement to meet these new requirements is in the lighting area. Kansas State University (KSU) in Manhattan, KS has had the same campus walkway lighting system for over 50 years and it does not meet the current energy codes and standards. This paper will perform a case study of the current walkway lighting system on the KSU campus, specifically focusing on the Quad area and applying the same principles to the entire campus. The illumination and fixture distribution characteristics will first be established and analyzed to determine an accurate baseline for later comparison. Issues regarding the illumination, efficiency, aesthetics, maintenance, and landscaping will be addressed once the current conditions are established. Lighting technology has changed dramatically in the past year with the development of high efficiency fluorescent, induction, and light emitting diode (LED) lighting. New LED technology has proven to be the most efficient and has been adapted to create outdoor LED fixtures that could help KSU surpass the current energy standards and improve the overall quality of light to correct some of the current issues the existing lighting creates. A full analysis of the illumination, efficiency, aesthetics, and economic feasibility will be performed. The economic analysis will compare existing maintenance and energy costs to that of the first-cost with maintenance, and energy costs to determine an estimated payback. Once the analysis is complete, future options for KSU to implement new lighting technology will be discussed. By creating a more environmentally conscious campus, using high efficiency lighting, KSU could set an example for other universities to pursue sustainable technology and design.

Recentes estudos sugerem a existência de sinapses elétricas mediadas por junções gap entre fotorreceptores na retina de vertebrados. Neste trabalho, descrevemos um modelo computacional dos circuitos primário e secundário mediados pelos bastonetes da retina de vertebrados. O modelo é composto pelas seguintes populações de células: bastonetes, cones, células bipolares dos bastonetes, células bipolares dos cones, células amácrinas do tipo AII e células ganglionares. As células do modelo estão acopladas entre si por sinapses químicas e elétricas segundo padrões realísticos de convergência e divergência. As sinapses elétricas ocorrem entre os bastonetes, entre os bastonetes e os cones, entre as células amácrinas AII e entre as células bipolares dos cones e a células amácrinas AII. O modelo assume que um estímulo luminoso de baixa intensidade, simulando condições escotópicas, atinge todos os bastonetes da camada receptora, porém menos da metade deles é excitada. A resposta dos bastonetes excitados é controlada por uma fotocorrente cuja amplitude pode ser alterada para simular estímulos de diferentes intensidades dentro da faixa escotópica. O modelo é utilizado para investigar os efeitos dos diferentes graus de acoplamento elétrico entre as células receptoras e entre as células amácrinas AII, além do efeito de diferentes valores de condutância do canal Ih ativado pela hiperpolarização nos bastonetes, sobre a faixa dinâmica da retina. Os resultados das simulações mostram que, para valores realísticos da condutância do canal Ih, a faixa dinâmica medida na camada receptora é maximizada para o índice de conectividade crítico para que haja percolação de ligação. No entanto, quando a faixa dinâmica é medida para as células bipolares ou ganglionares o valor máximo é obtido para um índice de conectividade subcrítico. Este resultado é conseqüência da alta convergência de sinapses químicas entre os bastonetes e células bipolares. / Recent studies suggest the existence of electrical synapses (gap junctions) connecting photoreceptors in the vertebrate retina. In this work we describe a computer model of the primary and secondary rod pathways in the vertebrate retina. The model is composed of the following cell populations: rods, cones, rod bipolar cells, cone bipolar cells, AII amacrine cells and ganglion cells. Cells of the model are connected via chemical as well as electrical synapses according to realistic convergence and divergence factors. There are electrical synapses between rods, rods and cones, AII amacrine cells, and cone bipolar cells and AII amacrine cells. The model assumes that low intensity stimuli simulating scotopic conditions reach all rods in the receptor array but less than half of them are excited. The excited rods response is controlled by a photocurrent waveform whose amplitude can be manipulated to simulate stimuli of different intensities within the scotopic range. The model is used to investigate the effects of different degrees of coupling among photoreceptors and among AII amacrine cells, as well as values of rod hyperpolarization activated current Ih on the dynamic range of the retina. Results show that for realistic values of Ih conductance the dynamic range of the rod array is maximized at the critical connectivity degree for bond percolation. However, the dynamic range of the rod bipolar and ganglion cells is maximized for a photoreceptor connectivity degree below the critical value. The latter result is a consequence of the high convergence of chemical synapses from rods to rod bipolar cells.

Recentes estudos sugerem a existência de sinapses elétricas mediadas por junções gap entre fotorreceptores na retina de vertebrados. Neste trabalho, descrevemos um modelo computacional dos circuitos primário e secundário mediados pelos bastonetes da retina de vertebrados. O modelo é composto pelas seguintes populações de células: bastonetes, cones, células bipolares dos bastonetes, células bipolares dos cones, células amácrinas do tipo AII e células ganglionares. As células do modelo estão acopladas entre si por sinapses químicas e elétricas segundo padrões realísticos de convergência e divergência. As sinapses elétricas ocorrem entre os bastonetes, entre os bastonetes e os cones, entre as células amácrinas AII e entre as células bipolares dos cones e a células amácrinas AII. O modelo assume que um estímulo luminoso de baixa intensidade, simulando condições escotópicas, atinge todos os bastonetes da camada receptora, porém menos da metade deles é excitada. A resposta dos bastonetes excitados é controlada por uma fotocorrente cuja amplitude pode ser alterada para simular estímulos de diferentes intensidades dentro da faixa escotópica. O modelo é utilizado para investigar os efeitos dos diferentes graus de acoplamento elétrico entre as células receptoras e entre as células amácrinas AII, além do efeito de diferentes valores de condutância do canal Ih ativado pela hiperpolarização nos bastonetes, sobre a faixa dinâmica da retina. Os resultados das simulações mostram que, para valores realísticos da condutância do canal Ih, a faixa dinâmica medida na camada receptora é maximizada para o índice de conectividade crítico para que haja percolação de ligação. No entanto, quando a faixa dinâmica é medida para as células bipolares ou ganglionares o valor máximo é obtido para um índice de conectividade subcrítico. Este resultado é conseqüência da alta convergência de sinapses químicas entre os bastonetes e células bipolares. / Recent studies suggest the existence of electrical synapses (gap junctions) connecting photoreceptors in the vertebrate retina. In this work we describe a computer model of the primary and secondary rod pathways in the vertebrate retina. The model is composed of the following cell populations: rods, cones, rod bipolar cells, cone bipolar cells, AII amacrine cells and ganglion cells. Cells of the model are connected via chemical as well as electrical synapses according to realistic convergence and divergence factors. There are electrical synapses between rods, rods and cones, AII amacrine cells, and cone bipolar cells and AII amacrine cells. The model assumes that low intensity stimuli simulating scotopic conditions reach all rods in the receptor array but less than half of them are excited. The excited rods response is controlled by a photocurrent waveform whose amplitude can be manipulated to simulate stimuli of different intensities within the scotopic range. The model is used to investigate the effects of different degrees of coupling among photoreceptors and among AII amacrine cells, as well as values of rod hyperpolarization activated current Ih on the dynamic range of the retina. Results show that for realistic values of Ih conductance the dynamic range of the rod array is maximized at the critical connectivity degree for bond percolation. However, the dynamic range of the rod bipolar and ganglion cells is maximized for a photoreceptor connectivity degree below the critical value. The latter result is a consequence of the high convergence of chemical synapses from rods to rod bipolar cells.

As real time visualizations become more realistic it also becomes more important to simulate the perceptual effects of the human visual system. Such effects include the response to varying illumination, glare and differences between photopic and scotopic vision. This thesis evaluates several different tone mapping methods to allow a greater dynamic range to be used in real time visualisations. Several tone mapping methods have been implemented in the Avalanche Game Engine and evaluated using a small test group. To increase immersion in the visualization several filters aimed to simulate perceptual effects has also been implemented. The primary goal of these filters is to simulate scotopic vision. The tests showed that two tone mapping methods would be suitable for the environment used in the tests. The S-curve tone mapping method gave the best result while the Mean Value method gave good results while being the simplest to implement and the cheapest. The test subjects agreed that the simulation of scotopic vision enhanced the immersion in a visualization. The primary difficulties in this work has been lack of dynamic range in the input images and the challenges in coding real time graphics using a graphics processing unit.

Age related macular degeneration (AMD) is one of the leading causes of blindness amongst the elderly. Macular pigment (MP) in the retina has been established to protect individuals against AMD. Improving levels of MP by diet or supplements is the constant quest of clinical practitioners and researchers, thus necessitating development of instruments capable of repeatable and reliable MP measurement. Cataract, a consequence of the rising opacity levels of the lens with age is one of the other major causes of blindness in the world. Mapcatsf, a LED-based microprocessor-controlled heterochromatic flicker photometer (HFP) using photopic vision is capable of measuring the levels of MP and the opacity of the lens in terms of optical density. Test-retest measurements conducted on 83 subjects were analyzed for repeatability in macular pigment optical density (MPOD) measurements. Reliability of the lens optical density (LOD) measurements were tested and compared with those obtained at absolute scotopic thresholds for 25 individuals. A supplement study with 32 individuals both in the young (50) age groups for 6 months further established Mapcatsf’s capacity to monitor changing levels of MP in individuals. As an overall outcome, high levels of repeatability and reliability were obtained in MPOD and LOD measurements establishing Mapcatsf as an instrument for use in clinical settings in the future.

Master of Science / Department of Architectural Engineering and Construction Science / Fred L. Hasler / This paper discusses photopic and scotopic vision of the human eye and the implications that could result in the design process of the lighting industry. The incorporation of scotopic vision in lighting effects the perceived illumination in all settings; but these affects and benefits are seen more prevalently at night, as this is when scotopic vision is utilized by the eye the most. The paper will begin with an overview of the eye including discussions of exactly what photopic and scotopic vision are, as well as how the eye works. This will lay a foundation for the paper to help the reader better comprehend and understand the remainder of the content. After the groundwork has been laid, the factors that affect how the eye perceives light will be discussed. These factors include pupil size and color of the light. A discussion of the basis for current lighting industry design and how light levels are measured will follow. Once these topics have been fully explored, there will be a discussion of the changes that could occur in the lighting industry if scotopic vision is taken into account. Increased energy efficiency would result if the scotopic vision is incorporated, resulting from the decrease in needed total lumen output. There have been a few applications that have utilized the effects of the scotopic vision in their design, these cases will be presented. Following the case study discussions, will be a discussion of a survey conducted by myself on the change-out of high pressure sodium (HPS) fixtures to LED fixtures in the downtown Poyntz Avenue area of Manhattan, KS. After all studies have been reviewed, conclusions and correlations among them will be explored. Following this analysis, suggestions will be given to improve the way lighting is designed in the industry.