Coming into contact with a case with clinical features of severe scurvy but having haematological features almost indistinguishable from severe pernicious anaemia, and yet obtaining an immediate and rapid haematological response to treatment with ascorbic acid, prompted me to consult the literature on the subject. Each new article read appeared to contradict the former so that I came away perplexed and confused. This confusion was easy to appreciate as deficiency of one vitamin usually means a deficiency in many other essential requirements. Consequently I felt that the dramatic haematological response was purely the result of supplying the necessary factor, in a case of nutritional macrocytic anaemia. This necessary factor was present in the full hospital diet given.

Thesis (Ph. D.)--Columbia University, 1929. / Vita. Bibliography: p. [22].

Yes / We read with interest the recent article by Charlier and colleagues entitled “The Mandible of Saint-Louis (1270 AD): Retrospective diagnosis and circumstances of death” [1]. This work, which consisted of macroscopic examination of a mandible purported to belong to the Crusader King of France and a review of historical accounts pertaining to his death, generated a good deal of press coverage and stimulated public interest in the fascinating field of palaeopathology. However, as researchers engaged in studying dental and nutritional disease in archaeological human remains we have some concerns with the methodology employed by the authors and the conclusions reached from the data they have collected. These include issues of provenance, lesion description, diagnostic methodology employed, and problems with historical references.

No

A thesis presented to the Faculty of Medicine, University of the Witwatersrand, in fulfilment of the requirements for the degree of Doctor of Medicine / Since changes occur in size, shape and haemoglobin content of red cells in disease a classification of the anaemias based on the morphology of the red cell has been widely used ( Wintrobe, 1956 ) . While such classification has a limited usefulness from the diagnostic and therapeutic approach it has two serious defects.. / IT2018

No / Recent analysis of the juvenile (≤12 years) human remains from a 19th century site in Wolverhampton, England revealed a relatively high level of nutritional deficiency diseases within the population. Indeed, 41.7% of the 48 juvenile skeletons analysed exhibited a combination of porous and proliferative bone lesions consistent with the pathological alterations associated with nutritional stress. This paper describes a pathological lesion on the inferior surface of the basilar portion of the occipital bone, not previously reported in association with infantile scurvy, but which was exhibited by 90% (N=9) of the 10 scorbutic individuals identified during this study.

Thesis (M.Sc.)--University of Alberta, 2009. / A thesis submitted to the Faculty of Graduate Studies and Research in partial fulfillment of the requirements for the degree of Master of Arts, Department of Anthropology. Title from pdf file main screen (viewed on July 30, 2009). Includes bibliographical references.

This thesis describes medical aspects of the expeditions of the Heroic Age of Antarctic exploration (1895-1922). It is divided into three sections. Section 1 describes the drugs and medical equipment taken to the Antarctic by these expeditions. There is an introductory discussion followed by papers on ophthalmic drugs, injections, inhalations and suppositories, oral drugs and topical preparations. Sledging medical cases are considered separately. Brandy was often used as a medicine and the medical uses of alcohol are described. Some expeditions took what were described as “medical comforts”. This term was sometimes used as a euphemism for alcoholic beverages but, in fact, encompassed a wide range of foods for invalids. Burroughs Wellcome and Co. supplied many of the expeditions with drugs and their medical chests. They used the expedition link in their advertising and the relationship between the expeditions and drug companies is described. Section 2 describes some of the medical problems encountered. The most serious problems were scurvy and a condition often called “polar anaemia”, which seems to be the same as a condition known at the time as “ship beriberi” and what is now described as “wet beriberi”. The controversy as to whether Captain Scott and his colleagues died of scurvy is also discussed. Other problems included frostbite and snow blindness. At least 11 general anaesthetics were given, including two for amputation of frostbitten toes. Psychological problems were common and there was some serious psychiatric illness including alcohol abuse. Section 3 describes the doctors and some of the research that they carried out. The most common research done by doctors was bacteriological. Most doctors collected biological data on the explorers including weights and haemoglobin measurements. This was largely for health monitoring but one doctor pursued physiological research. Three doctors and a medical student studied geology.

No description available.

Historically, scurvy has seen only minor investigation in children. This is also true among archaeological populations. The development of criteria for assessing juvenile scurvy among archaeological populations has provided a novel means of paleopathological analysis for discussing this disorder among past populations. In an attempt to further investigate the current criteria for identifying archaeological cases of juvenile scurvy, as proposed by Ortner et al. (2001, 1999; Ortner and Ericksen 1997; Ortner 1984), a combined macroscopic and radiographic study was conducted on the sub-adult individuals from late Roman–Byzantine Stymphalos and Frankish Zaraka, Greece. This study sought to investigate the level of correlation between the proposed macroscopic and clinically employed radiographic indicators of juvenile scurvy. From the research conducted there is clear evidence to suggest a significant level of correlation between the proposed macroscopic and radiographic indicators of juvenile scurvy. Such a correlation supports the current osteoarchaeological criteria for assessing juvenile scurvy.