Thesis (M. Sc.)--University of Hong Kong, 1995. / Includes bibliographical references.

Abstract This study concerns contents of several organotin compounds, monobutyltin (MBT), dibutyltin (DBT), tributyltin (TBT), monophenyltin (MPhT), diphenyltin (DPhT) and triphenyltin (TPhT), in seafood. Seafood samples were collected from markets and coastal zone in Taiwan, and contents of organotins were analyzed by Grignard reagent derivation coupled with GC/FPD. Besides, the tolerable daily intake (TDI) of (TBT+DBT), mean body weight of Taiwan citizen and the consumption of seafood were used to derive the tolerable average residue level (TARL) of the compounds. The risk assessment was implemented by comparing the content to TARL. The contents of TBT, DBT, MBT, TPhT, DPhT and MPhT in seafood ranged N. D~48.36 ng Sn/g wet wt., N. D~36.68 ng Sn/g wet wt., N. D~79.19 ng Sn/g wet wt., N. D~225.53 ng Sn/g wet wt., N. D~128.16 ng Sn/g wet wt., N. D ~ 95.44 ng Sn/g wet wt., respectively. Reference survey showed that mean body weight of Taiwan citizen is 54.42 Kg, and seafood consumption rate is 127.59 g/day/person. A TARL of 44.27 ng Sn/g wet wt. is derived accordingly. Of all the 71 samples, only 4 contain more (TBT+DBT) than the TARL. On the other hand, (TBT+DBT) contents weighed by consumed ratio averaged 3.87 ng Sn/g wet wt., which is far under the TARL. Different visions lead to the same conclusion that (TBT+DBT) content of seafood in Taiwan is far away from dangerous level. This study also concluded that cooking process doesn¡¦t affect the contents of organotin compounds of seafood, and the Grignard reagents contribute to the TBT blank signal. Furthermore, the independence between organotins and factors such as classifications, sampling area or habitat was discussed.

Graduation date: 1950

Graduation date: 1961

Thesis (M.S.)--Oregon State University, 2009. / Printout. Includes bibliographical references (leaves 87-94). Also available on the World Wide Web.

Thesis (M.M.P.)--University of Delaware, 2007. / Principal faculty advisor: Lee G. Anderson, College of Marine and Earth Studies. Includes bibliographical references.

Thesis (M.Sc.)--Memorial University of Newfoundland, 2001. / Restricted until June 2002. Bibliography: leaves [145]-167.

Thesis (M. Sc.)--University of Hong Kong, 1996. / Includes bibliographical references (leaf 57-60).

Toxic/mutagenic potentials of Gambierdiscus toxicus (GT) and Prorocentrum lima (PL) methanol extracts (CME) were determined using brine shrimp (Artemia salina), mouse, chicken embryo and Salmonella microsomal assays. PL-CME and GT-CME were toxic to shrimp and mice. Isolation and separation were accomplished using ether/water, hexane/methanol partition and butanol extraction. Toxic fractions were purified using column and thin layer chromatography (TLC). GT-CME showed low levels of mutagenic potential. For GT isolated fractions and PL-CME, no mutagenic effects were observed. Both CMEs showed embryotoxicity, with no teratogenic effects. Ether/methanol and water/butanol fractions showed shrimp toxicity. These fractions were purified by treatment with warm/cold acetone. Acetone insoluble precipitates were obtained. Ether soluble acetone filtrate (ESAF) and butanol soluble acetone precipitate (BSAP) showed shrimp and mouse toxicity. GT-BSAP produced temperature depression in mice. Three toxic isolates were obtained from PL-ESAF, four from GT-ESAF and one from both BSAPs columns. TLC preparative plates showed at least 12 toxic isolates for PL-ESAF, 8 for GT-ESAF and 4 for GT-BSAP.

Thesis (Ph. D.)--University of Oregon, 2001. / Typescript. Includes vita and abstract. Includes bibliographical references (leaves 143-163). Also available for download via the World Wide Web; free to University of Oregon users.