In 5G systems, two radio air interfaces, evolved LTE and New Radio (NR), will coexist. By using millimeter waves, NR will provide high throughputs, but the higher frequencies will also lead to increased losses and a worse coverage. Multi-connectivity is therefore envisioned as a way to tackle these effects by connecting to multiple base stations simultaneously, allowing users to benefit from both air interfaces’ advantages. In this thesis, we investigate how multi-connectivity can be used efficiently in ultra-dense networks, a new paradigm in which the number of access nodes exceeds the number of users within the network. A framework for secondary cell association is presented and an energy efficiency’s condition is proposed. Upper and lower bounds of the network’s energy efficiency are analytically expressed. Algorithms for secondary cell selection are designed and evaluated through simulations. Multi-connectivity showed an improvement of up to 50% in reliability and and an increase of up to 20% in energy efficiency.