The present study proposed to investigate the effects of level of acculturation and of language of the therapy interview on self-disclosure by Mexican-American women. It was predicted that self-disclosure would be affected by both level of acculturation and by the language of the initial therapy interview. The principal implication of this finding is that for the first-generation Mexican-American woman, that is, a woman who has not acculturated to the mainstream society, the language in which therapy is conducted constitutes a significant factor in predicting whether she is likely to self disclose and thereby benefit from the therapy. The findings of this study suggest that less acculturated Mexican-American women would be more likely to utilize mental health services if they are available in Spanish.