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Modeling of High-Dimensional Clinical Longitudinal Oxygenation Data from Retinopathy of PrematurityMargevicius, Seunghee P. 01 June 2018 (has links)
No description available.
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Two Essays on Equity Mutual FundsJaiprakash, Puneet 08 September 2011 (has links)
Previous research has shown that expected market returns vary over time and that this variation can be predicted by variables such as dividend yields and book-to-market ratios (Fama and French (1989); Campbell and Thompson (2008)). Further, macroeconomic variables affect asset returns (Flannery and Protopapadikas (2002)). We investigate whether the investment decisions of mutual fund investors incorporate information about future stock returns contained in predictive and macroeconomic variables. If investors incorporate this information, then variation in flows should be related to that in predictive variables and macroeconomic variables. Using quarterly flow data from 1951Q4 to 2007Q4, we find that both predictive and macroeconomic variables have a relatively small impact on flows. Our results suggest that fund investors, as a group, fail to adequately incorporate the information contained in these variables.
Existing literature documents that (i) an asymmetric low-performance relationship creates an incentive for managers to extract rents from shareholders, and (ii) managers respond to such incentives by strategically altering portfolio risk. Using the semiparametric regression model proposed by Chevalier and Ellison (1997), we show that the flow-performance relationship has become linear in recent years (2000-2009) and fund managers no longer respond to such incentives. Fund managers, however, change portfolio risk in response to past performance; such changes have a positive impact on fund performance and are indicative of a better alignment of interests between managers and shareholders. / Ph. D.
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Estimação não-paramétrica e semi-paramétrica de fronteiras de produçãoTorrent, Hudson da Silva January 2010 (has links)
Existe uma grande e crescente literatura sobre especificação e estimação de fronteiras de produção e, portanto, de eficiência de unidades produtivas. Nesta tese, o foco esta sobre modelos de fronteiras determinísticas, os quais são baseados na hipótese de que os dados observados pertencem ao conjunto tecnológico. Dentre os modelos estatísticos e estimadores para fronteiras determinísticas existentes, uma abordagem promissora e a adotada por Martins-Filho e Yao (2007). Esses autores propõem um procedimento de estimação composto por três estágios. Esse estimador e de fácil implementação, visto que envolve procedimentos não-paramétricos bem conhecidos. Além disso, o estimador possui características desejáveis vis-à-vis estimadores para fronteiras determinísticas tradicionais como DEA e FDH. Nesta tese, três artigos, que melhoram o modelo proposto por Martins-Filho e Yao (2007), sao propostos. No primeiro artigo, o procedimento de estimação desses autores e melhorado a partir de uma variação do estimador exponencial local, proposto por Ziegelmann (2002). Demonstra-se que estimador proposto a consistente e assintoticamente normal. Além disso, devido ao estimador exponencial local, estimativas potencialmente negativas para a função de variância condicional, que poderiam prejudicar a aplicabilidade do estimador proposto por Martins-Filho e Yao, são evitadas. No segundo artigo, e proposto um método original para estimação de fronteiras de produção em apenas dois estágios. E mostrado que se pode eliminar o segundo estágio proposto por Martins-Filho e Yao, assim como, eliminar o segundo estagio proposto no primeiro artigo desta tese. Em ambos os casos, a estimação do mesmo modelo de fronteira de produção requer três estágios, sendo versões diferentes para o segundo estagio. As propriedades assintóticas do estimador proposto são analisadas, mostrando-se consistência e normalidade assintótica sob hipóteses razoáveis. No terceiro artigo, a proposta uma variação semi-paramétrica do modelo estudado no segundo artigo. Reescreve-se aquele modelo de modo que se possa estimar a fronteira de produção e a eficiência de unidades produtivas no contexto de múltiplos insumos, sem incorrer no curse of dimensionality. A abordagem adotada coloca o modelo na estrutura de modelos aditivos, a partir de hipóteses sobre como os insumos se combinam no processo produtivo. Em particular, considera-se aqui os casos de insumos aditivos e insumos multiplicativos, os quais são amplamente considerados em teoria econômica e aplicações. Estudos de Monte Carlo são apresentados em todos os artigos, afim de elucidar as propriedades dos estimadores propostos em amostras finitas. Além disso, estudos com dados reais são apresentados em todos os artigos, nos quais são estimador rankings de eficiência para uma amostra de departamentos policiais dos EUA, a partir de dados sobre criminalidade daquele país. / There exists a large and growing literature on the specification and estimation of production frontiers and therefore efficiency of production units. In this thesis we focus on deterministic production frontier models, which are based on the assumption that all observed data lie in the technological set. Among the existing statistical models and estimators for deterministic frontiers, a promising approach is that of Martins-Filho and Yao (2007). They propose an estimation procedure that consists of three stages. Their estimator is fairly easy to implement as it involves standard nonparametric procedures. In addition, it has a number of desirable characteristics vis-a-vis traditional deterministic frontier estimators as DEA and FDH. In this thesis we propose three papers that improve the model proposed in Martins-Filho and Yao (2007). In the first paper we improve their estimation procedure by adopting a variant of the local exponential smoothing proposed in Ziegelmann (2002). Our estimator is shown to be consistent and asymptotically normal. In addition, due to local exponential smoothing, potential negativity of conditional variance functions that may hinder the use of Martins-Filho and Yao's estimator is avoided. In the second paper we propose a novel method for estimating production frontiers in only two stages. (Continue). There we show that we can eliminate the second stage of Martins-Filho and Yao as well as of our first paper, where estimation of the same frontier model requires three stages under different versions for the second stage. We study asymptotic properties showing consistency andNirtnin, asymptotic normality of our proposed estimator under standard assumptions. In the third paper we propose a semiparametric variation of the frontier model studied in the second paper. We rewrite that model allowing for estimating the production frontier and efficiency of production units in a multiple input context without suffering the curse of dimensionality. Our approach places that model within the framework of additive models based on assumptions regarding the way inputs combine in production. In particular, we consider the cases of additive and multiplicative inputs, which are widely considered in economic theory and applications. Monte Carlo studies are performed in all papers to shed light on the finite sample properties of the proposed estimators. Furthermore a real data study is carried out in all papers, from which we rank efficiency within a sample of USA Law Enforcement agencies using USA crime data.
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Testing for spatial correlation and semiparametric spatial modeling of binary outcomes with application to aberrant crypt foci in colon carcinogenesis experimentsApanasovich, Tatiyana Vladimirovna 01 November 2005 (has links)
In an experiment to understand colon carcinogenesis, all animals were exposed to a carcinogen while half the animals were also exposed to radiation. Spatially, we measured the existence of aberrant crypt foci (ACF), namely morphologically changed colonic crypts that are known to be precursors of colon cancer development. The biological question of interest is whether the locations of these ACFs are spatially correlated: if so, this indicates that damage to the colon due to carcinogens and radiation is localized. Statistically, the data take the form of binary outcomes (corresponding to the existence of an ACF) on a regular grid. We develop score??type methods based upon the Matern and conditionally autoregression (CAR) correlation models to test for the spatial correlation in such data, while allowing for nonstationarity. Because of a technical peculiarity of the score??type test, we also develop robust versions of the method. The methods are compared to a generalization of Moran??s test for continuous outcomes, and are shown via simulation to have the potential for increased power. When applied to our data, the methods indicate the existence of spatial correlation, and hence indicate localization of damage. Assuming that there are correlations in the locations of the ACF, the questions are how great are these correlations, and whether the correlation structures di?er when an animal is exposed to radiation. To understand the extent of the correlation, we cast the problem as a spatial binary regression, where binary responses arise from an underlying Gaussian latent process. We model these marginal probabilities of ACF semiparametrically, using ?xed-knot penalized regression splines and single-index models. We ?t the models using pairwise pseudolikelihood methods. Assuming that the underlying latent process is strongly mixing, known to be the case for many Gaussian processes, we prove asymptotic normality of the methods. The penalized regression splines have penalty parameters that must converge to zero asymptotically: we derive rates for these parameters that do and do not lead to an asymptotic bias, and we derive the optimal rate of convergence for them. Finally, we apply the methods to the data from our experiment.
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General conditional linear models with time-dependent coefficients under censoring and truncationTeodorescu, Bianca 19 December 2008 (has links)
In survival analysis interest often lies in the relationship between the survival function and a certain number of covariates. It usually happens that for some individuals we cannot observe the event of interest, due to the presence of right censoring and/or left truncation. A typical example is given by a retrospective medical study, in which one is interested in the time interval between birth and death due to a certain disease. Patients who die of the disease at early age will rarely have entered the study before death and are therefore left truncated. On the other hand, for patients who are alive at the end of the study, only a lower bound of the true survival time is known and these patients are hence right censored.
In the case of censored and/or truncated responses, lots of models exist in the literature that describe the relationship between the survival function and the covariates (proportional hazards model or Cox model, log-logistic model, accelerated failure time model, additive risks model, etc.). In these models, the regression coefficients are usually supposed to be constant over time. In practice, the structure of the data might however be more complex, and it might therefore be better to consider coefficients that can vary over time. In the previous examples, certain covariates (e.g. age at diagnosis, type of surgery, extension of tumor, etc.) can have a relatively high impact on early age survival, but a lower influence at higher age. This motivated a number of authors to extend the Cox model to allow for time-dependent coefficients or consider other type of time-dependent coefficients models like the additive hazards model.
In practice it is of great use to have at hand a method to check the validity of the above mentioned models.
First we consider a very general model, which includes as special cases the above mentioned models (Cox model, additive model, log-logistic model, linear transformation models, etc.) with time-dependent coefficients and study the parameter estimation by means of a least squares approach. The response is allowed to be subject to right censoring and/or left truncation.
Secondly we propose an omnibus goodness-of-fit test that will test if the general time-dependent model considered above fits the data. A bootstrap version, to approximate the critical values of the test is also proposed.
In this dissertation, for each proposed method, the finite sample performance is evaluated in a simulation study and then applied to a real data set.
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Testing for spatial correlation and semiparametric spatial modeling of binary outcomes with application to aberrant crypt foci in colon carcinogenesis experimentsApanasovich, Tatiyana Vladimirovna 01 November 2005 (has links)
In an experiment to understand colon carcinogenesis, all animals were exposed to a carcinogen while half the animals were also exposed to radiation. Spatially, we measured the existence of aberrant crypt foci (ACF), namely morphologically changed colonic crypts that are known to be precursors of colon cancer development. The biological question of interest is whether the locations of these ACFs are spatially correlated: if so, this indicates that damage to the colon due to carcinogens and radiation is localized. Statistically, the data take the form of binary outcomes (corresponding to the existence of an ACF) on a regular grid. We develop score??type methods based upon the Matern and conditionally autoregression (CAR) correlation models to test for the spatial correlation in such data, while allowing for nonstationarity. Because of a technical peculiarity of the score??type test, we also develop robust versions of the method. The methods are compared to a generalization of Moran??s test for continuous outcomes, and are shown via simulation to have the potential for increased power. When applied to our data, the methods indicate the existence of spatial correlation, and hence indicate localization of damage. Assuming that there are correlations in the locations of the ACF, the questions are how great are these correlations, and whether the correlation structures di?er when an animal is exposed to radiation. To understand the extent of the correlation, we cast the problem as a spatial binary regression, where binary responses arise from an underlying Gaussian latent process. We model these marginal probabilities of ACF semiparametrically, using ?xed-knot penalized regression splines and single-index models. We ?t the models using pairwise pseudolikelihood methods. Assuming that the underlying latent process is strongly mixing, known to be the case for many Gaussian processes, we prove asymptotic normality of the methods. The penalized regression splines have penalty parameters that must converge to zero asymptotically: we derive rates for these parameters that do and do not lead to an asymptotic bias, and we derive the optimal rate of convergence for them. Finally, we apply the methods to the data from our experiment.
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Credit Scoring Methods And Accuracy RatioIscanoglu, Aysegul 01 August 2005 (has links) (PDF)
The credit scoring with the help of classification techniques provides to take easy and quick decisions in lending. However, no definite consensus has been reached with regard to the best method for credit scoring and in what conditions the methods performs best. Although a huge range of classification techniques has been used in this area, the logistic regression has been seen an important tool and used
very widely in studies. This study aims to examine accuracy and bias properties in parameter estimation of the logistic regression by using Monte Carlo simulations in four aspect which are dimension of the sets, length, the included percentage defaults in data and effect of variables on estimation. Moreover, application of some important statistical and non-statistical methods on Turkish credit default
data is provided and the method accuracies are compared for Turkish market. Finally, ratings on the results of best method is done by using receiver operating characteristic curve.
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Estimação não-paramétrica e semi-paramétrica de fronteiras de produçãoTorrent, Hudson da Silva January 2010 (has links)
Existe uma grande e crescente literatura sobre especificação e estimação de fronteiras de produção e, portanto, de eficiência de unidades produtivas. Nesta tese, o foco esta sobre modelos de fronteiras determinísticas, os quais são baseados na hipótese de que os dados observados pertencem ao conjunto tecnológico. Dentre os modelos estatísticos e estimadores para fronteiras determinísticas existentes, uma abordagem promissora e a adotada por Martins-Filho e Yao (2007). Esses autores propõem um procedimento de estimação composto por três estágios. Esse estimador e de fácil implementação, visto que envolve procedimentos não-paramétricos bem conhecidos. Além disso, o estimador possui características desejáveis vis-à-vis estimadores para fronteiras determinísticas tradicionais como DEA e FDH. Nesta tese, três artigos, que melhoram o modelo proposto por Martins-Filho e Yao (2007), sao propostos. No primeiro artigo, o procedimento de estimação desses autores e melhorado a partir de uma variação do estimador exponencial local, proposto por Ziegelmann (2002). Demonstra-se que estimador proposto a consistente e assintoticamente normal. Além disso, devido ao estimador exponencial local, estimativas potencialmente negativas para a função de variância condicional, que poderiam prejudicar a aplicabilidade do estimador proposto por Martins-Filho e Yao, são evitadas. No segundo artigo, e proposto um método original para estimação de fronteiras de produção em apenas dois estágios. E mostrado que se pode eliminar o segundo estágio proposto por Martins-Filho e Yao, assim como, eliminar o segundo estagio proposto no primeiro artigo desta tese. Em ambos os casos, a estimação do mesmo modelo de fronteira de produção requer três estágios, sendo versões diferentes para o segundo estagio. As propriedades assintóticas do estimador proposto são analisadas, mostrando-se consistência e normalidade assintótica sob hipóteses razoáveis. No terceiro artigo, a proposta uma variação semi-paramétrica do modelo estudado no segundo artigo. Reescreve-se aquele modelo de modo que se possa estimar a fronteira de produção e a eficiência de unidades produtivas no contexto de múltiplos insumos, sem incorrer no curse of dimensionality. A abordagem adotada coloca o modelo na estrutura de modelos aditivos, a partir de hipóteses sobre como os insumos se combinam no processo produtivo. Em particular, considera-se aqui os casos de insumos aditivos e insumos multiplicativos, os quais são amplamente considerados em teoria econômica e aplicações. Estudos de Monte Carlo são apresentados em todos os artigos, afim de elucidar as propriedades dos estimadores propostos em amostras finitas. Além disso, estudos com dados reais são apresentados em todos os artigos, nos quais são estimador rankings de eficiência para uma amostra de departamentos policiais dos EUA, a partir de dados sobre criminalidade daquele país. / There exists a large and growing literature on the specification and estimation of production frontiers and therefore efficiency of production units. In this thesis we focus on deterministic production frontier models, which are based on the assumption that all observed data lie in the technological set. Among the existing statistical models and estimators for deterministic frontiers, a promising approach is that of Martins-Filho and Yao (2007). They propose an estimation procedure that consists of three stages. Their estimator is fairly easy to implement as it involves standard nonparametric procedures. In addition, it has a number of desirable characteristics vis-a-vis traditional deterministic frontier estimators as DEA and FDH. In this thesis we propose three papers that improve the model proposed in Martins-Filho and Yao (2007). In the first paper we improve their estimation procedure by adopting a variant of the local exponential smoothing proposed in Ziegelmann (2002). Our estimator is shown to be consistent and asymptotically normal. In addition, due to local exponential smoothing, potential negativity of conditional variance functions that may hinder the use of Martins-Filho and Yao's estimator is avoided. In the second paper we propose a novel method for estimating production frontiers in only two stages. (Continue). There we show that we can eliminate the second stage of Martins-Filho and Yao as well as of our first paper, where estimation of the same frontier model requires three stages under different versions for the second stage. We study asymptotic properties showing consistency andNirtnin, asymptotic normality of our proposed estimator under standard assumptions. In the third paper we propose a semiparametric variation of the frontier model studied in the second paper. We rewrite that model allowing for estimating the production frontier and efficiency of production units in a multiple input context without suffering the curse of dimensionality. Our approach places that model within the framework of additive models based on assumptions regarding the way inputs combine in production. In particular, we consider the cases of additive and multiplicative inputs, which are widely considered in economic theory and applications. Monte Carlo studies are performed in all papers to shed light on the finite sample properties of the proposed estimators. Furthermore a real data study is carried out in all papers, from which we rank efficiency within a sample of USA Law Enforcement agencies using USA crime data.
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Estimação não-paramétrica e semi-paramétrica de fronteiras de produçãoTorrent, Hudson da Silva January 2010 (has links)
Existe uma grande e crescente literatura sobre especificação e estimação de fronteiras de produção e, portanto, de eficiência de unidades produtivas. Nesta tese, o foco esta sobre modelos de fronteiras determinísticas, os quais são baseados na hipótese de que os dados observados pertencem ao conjunto tecnológico. Dentre os modelos estatísticos e estimadores para fronteiras determinísticas existentes, uma abordagem promissora e a adotada por Martins-Filho e Yao (2007). Esses autores propõem um procedimento de estimação composto por três estágios. Esse estimador e de fácil implementação, visto que envolve procedimentos não-paramétricos bem conhecidos. Além disso, o estimador possui características desejáveis vis-à-vis estimadores para fronteiras determinísticas tradicionais como DEA e FDH. Nesta tese, três artigos, que melhoram o modelo proposto por Martins-Filho e Yao (2007), sao propostos. No primeiro artigo, o procedimento de estimação desses autores e melhorado a partir de uma variação do estimador exponencial local, proposto por Ziegelmann (2002). Demonstra-se que estimador proposto a consistente e assintoticamente normal. Além disso, devido ao estimador exponencial local, estimativas potencialmente negativas para a função de variância condicional, que poderiam prejudicar a aplicabilidade do estimador proposto por Martins-Filho e Yao, são evitadas. No segundo artigo, e proposto um método original para estimação de fronteiras de produção em apenas dois estágios. E mostrado que se pode eliminar o segundo estágio proposto por Martins-Filho e Yao, assim como, eliminar o segundo estagio proposto no primeiro artigo desta tese. Em ambos os casos, a estimação do mesmo modelo de fronteira de produção requer três estágios, sendo versões diferentes para o segundo estagio. As propriedades assintóticas do estimador proposto são analisadas, mostrando-se consistência e normalidade assintótica sob hipóteses razoáveis. No terceiro artigo, a proposta uma variação semi-paramétrica do modelo estudado no segundo artigo. Reescreve-se aquele modelo de modo que se possa estimar a fronteira de produção e a eficiência de unidades produtivas no contexto de múltiplos insumos, sem incorrer no curse of dimensionality. A abordagem adotada coloca o modelo na estrutura de modelos aditivos, a partir de hipóteses sobre como os insumos se combinam no processo produtivo. Em particular, considera-se aqui os casos de insumos aditivos e insumos multiplicativos, os quais são amplamente considerados em teoria econômica e aplicações. Estudos de Monte Carlo são apresentados em todos os artigos, afim de elucidar as propriedades dos estimadores propostos em amostras finitas. Além disso, estudos com dados reais são apresentados em todos os artigos, nos quais são estimador rankings de eficiência para uma amostra de departamentos policiais dos EUA, a partir de dados sobre criminalidade daquele país. / There exists a large and growing literature on the specification and estimation of production frontiers and therefore efficiency of production units. In this thesis we focus on deterministic production frontier models, which are based on the assumption that all observed data lie in the technological set. Among the existing statistical models and estimators for deterministic frontiers, a promising approach is that of Martins-Filho and Yao (2007). They propose an estimation procedure that consists of three stages. Their estimator is fairly easy to implement as it involves standard nonparametric procedures. In addition, it has a number of desirable characteristics vis-a-vis traditional deterministic frontier estimators as DEA and FDH. In this thesis we propose three papers that improve the model proposed in Martins-Filho and Yao (2007). In the first paper we improve their estimation procedure by adopting a variant of the local exponential smoothing proposed in Ziegelmann (2002). Our estimator is shown to be consistent and asymptotically normal. In addition, due to local exponential smoothing, potential negativity of conditional variance functions that may hinder the use of Martins-Filho and Yao's estimator is avoided. In the second paper we propose a novel method for estimating production frontiers in only two stages. (Continue). There we show that we can eliminate the second stage of Martins-Filho and Yao as well as of our first paper, where estimation of the same frontier model requires three stages under different versions for the second stage. We study asymptotic properties showing consistency andNirtnin, asymptotic normality of our proposed estimator under standard assumptions. In the third paper we propose a semiparametric variation of the frontier model studied in the second paper. We rewrite that model allowing for estimating the production frontier and efficiency of production units in a multiple input context without suffering the curse of dimensionality. Our approach places that model within the framework of additive models based on assumptions regarding the way inputs combine in production. In particular, we consider the cases of additive and multiplicative inputs, which are widely considered in economic theory and applications. Monte Carlo studies are performed in all papers to shed light on the finite sample properties of the proposed estimators. Furthermore a real data study is carried out in all papers, from which we rank efficiency within a sample of USA Law Enforcement agencies using USA crime data.
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Some Advanced Semiparametric Single-index Modeling for Spatially-Temporally Correlated DataMahmoud, Hamdy F. F. 09 October 2014 (has links)
Semiparametric modeling is a hybrid of the parametric and nonparametric modelings where some function forms are known and others are unknown. In this dissertation, we have made several contributions to semiparametric modeling based on the single index model related to the following three topics: the first is to propose a model for detecting change points simultaneously with estimating the unknown function; the second is to develop two models for spatially correlated data; and the third is to further develop two models for spatially-temporally correlated data.
To address the first topic, we propose a unified approach in its ability to simultaneously estimate the nonlinear relationship and change points. We propose a single index change point model as our unified approach by adjusting for several other covariates. We nonparametrically estimate the unknown function using kernel smoothing and also provide a permutation based testing procedure to detect multiple change points. We show the asymptotic properties of the permutation testing based procedure. The advantage of our approach is demonstrated using the mortality data of Seoul, Korea from January, 2000 to December, 2007.
On the second topic, we propose two semiparametric single index models for spatially correlated data. One additively separates the nonparametric function and spatially correlated random effects, while the other does not separate the nonparametric function and spatially correlated random effects. We estimate these two models using two algorithms based on Markov Chain Expectation Maximization algorithm. Our approaches are compared using simulations, suggesting that the semiparametric single index nonadditive model provides more accurate estimates of spatial correlation. The advantage of our approach is demonstrated using the mortality data of six cities, Korea from January, 2000 to December, 2007.
The third topic involves proposing two semiparametric single index models for spatially and temporally correlated data. Our first model has the nonparametric function which can separate from spatially and temporally correlated random effects. We refer it to "semiparametric spatio-temporal separable single index model (SSTS-SIM)", while the second model does not separate the nonparametric function from spatially correlated random effects but separates the time random effects. We refer our second model to "semiparametric nonseparable single index model (SSTN-SIM)". Two algorithms based on Markov Chain Expectation Maximization algorithm are introduced to simultaneously estimate parameters, spatial effects, and times effects. The proposed models are then applied to the mortality data of six major cities in Korea. Our results suggest that SSTN-SIM is more flexible than SSTS-SIM because it can estimate various nonparametric functions while SSTS-SIM enforces the similar nonparametric curves. SSTN-SIM also provides better estimation and prediction. / Ph. D.
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