Romantic relationships commonly endure rough patches. The relational turbulence model and the social allergy phenomenon may account for such rough transitions. A social allergy is an idiosyncratic social behavior that involuntarily stirs up irritation in an individual, either with or without the intention of the transgressor. As the behavior is repeated, tolerance for the bothersome allergen dwindles. This paper investigates the connections between relational turbulence and social allergies. The relational turbulence model describes individuals’ severe reactions to various turning points in an interpersonal relationship, and combines the effects of increased intimacy, relational uncertainty, and partner interference. Based on the turbulence model, the author predicted curvilinear relationships between intimacy and social allergen occurrence as well as between intimacy and negative emotional impact of social allergens. Based on the social allergen literature, the author predicted social allergen occurrence and repeated arguments about social allergens would both associate positively with relationship turbulence. Partial support was found for each prediction.