This paper addresses the harmful effects of concentrated animal feeding operations (CAFOs) within animal farming systems, including poor animal welfare, environmental damage, and environmental injustice. I argue that bioregionalism and socialist ecofeminism can help inform a holistic approach to mitigating these harms and evoke ethical and sustainable animal farming systems. Bioregionalism emphasizes local resource use, community engagement, and ecological knowledge within a specific region, while socialist ecofeminism critiques oppressive systems and seeks to uplift the viewpoints of all beings, including animals, nature, and humans of various identities. Through a scaffolded hypothetical case study informed by the CAFOs-practicing hog farms in the coastal plain of North Carolina, I examine the potential benefits and limitations of a solely bioregional animal farming system followed by the potential benefits and limitations of a solely socialist ecofeminist animal farming system. I then combine the two theories to explore how they complement one another. I conclude that an ecologically informed structure advocated by bioregionalism functioning together with the moral values of socialist ecofeminism creates the possibility for ethical and sustainable animal farming systems.