Made available in DSpace on 2014-06-11T19:32:22Z (GMT). No. of bitstreams: 0 Previous issue date: 2011-03-15Bitstream added on 2014-06-13T21:04:11Z : No. of bitstreams: 1 uceda_ra_dr_sjrp.pdf: 905373 bytes, checksum: c2f0ae66c1c9b9621f826e692c6d9b4c (MD5) / Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) / Em 2000, Killeen e Taylor definiram a máquina de somar estocástica em base 2. Eles mostraram que o espectro do op erador de transi cão (agindo em l∞( N)), associado a essa máquina, e igual ao conjunto de Julia cheio de uma função quadrática. Nesse trabalho, estudamos outras propriedades espectrais e topológicass da máquina de Killeen e Taylor, e também das suas extensões à l∞(Z) e a outras bases não constantes. Esse estudo envolve conjuntos de Julia de funções quadráticas e também conjuntos de Julia cheios de endomor smos de C2 . Finalmente estudamos algumas propriedades aritméticas e topológicas de uma classe de fractais de Rauzy. Em particular estudamos o azulejamento periódico do plano complexo C induzido por eles. / In 2000, Killeen and Taylor de ned the sto hastic adding machine in base 2. They proved that the sp ectrum of the transition op erator (acting in l∞(N )) asso ciated to this machine is equal to the lled Julia set of a quadratic polynomial map. In this work, we study other sp ectral and top ological prop erties of Killeen and Taylor machine, and also of its extensions to l∞( Z) and to other non constant bases. This study envolves Julia sets of quadratic maps and also lled Julia sets of endomorphisms of C2 . Finally we study some arithmetical and topological prop erties of a class of Rauzy fractals. In particular we study the p erio dictiling of complex plane C induced by this class.

Transport across the membrane of a cell is of crucial importance for cellular functions. The solute carrier family,SLC38 is a family of membrane proteins that transports various substances through the membrane and thusperforms many physiologically important functions, for example, transport of glutamine from astrocyte toneurons in the central nervous system. In this paper, we demonstrate that one of the transporters in this familynamed SLC38A6 forms several protein complexes with a variety of proteins in the membrane and in synapticvesicles, suggesting that SLC38A6 is involved in the synaptic release of neurotransmitters in synapses. Weperformed sensitive protein interaction analysis between the protein of interest and a variety of proteinsexpressed at different sites in the neuronal cell. We showed that SLC38A6 interacts with proteins in the cellmembrane as well as in the membrane of synaptic vesicles. The current theory is that SLC38A6 interact withthese proteins when the synaptic vesicles are in close proximity with the cell membrane during the release of theneurotransmitters.