The effect of a low-Cu diet supplied to gilts during pregnancy and early lactation on dams and their offspring was obtained in seven pairs of first littermate gilts. They were housed in stainless steel metabolism cages in a controlled environment and fed semi-purified diets containing either 2.13 or 12.25 ppm Cu from 30 days of gestation through two weeks of lactation. Feed intake was restricted to 2 kg/day during pregnancy and 4 kg/day in the first two weeks of lactation. Reproductive performance of gilts was measured. Balance studies were conducted at 30, 60 and 100 days of gestation. Mineral levels in the plasma of gilts and piglets, and in colostrum and milk were determined. The low-Cu diet did not affect (p $>$ 0.05) weight changes during pregnancy. The duration of parturition was shorter for low-Cu than for control gilts (3.19h vs 5.71h, p 0.05). Low-Cu gilts had lower plasma Cu in early- and mid-gestation and farrowed piglets with lower plasma Cu and higher plasma Zn concentrations (p 0.05). Plasma Cu and Fe levels of newborn piglets were lower than those of their dams (p 0.05). Low-Cu gilts had lower Cu and higher Zn content in colostrum and also lower Cu in milk than control gilts (p 0.05). Colostrum was richer in Cu and Zn than milk (p 0.05). Higher dry matter digestibility was observed in low-Cu gilts during early gestation (p 0.05). Compared to control gilts, the low-Cu gilts tended to have higher Cu and Zn retention which was achieved by reduction of fecal Cu and Zn excretion. Utilization of minerals appeared to increase as pregnancy progressed.

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Typescript (photocopy). Thesis submitted under title: Biochemical aspects of early pregnancy in the pig; but doctorate conferred to title: Biochemical aspects of early pregnancy in the sow Includes bibliographical references (leaves 178-205) and list of personal publications related to pig physiology (leaves vi-vii) Examines aspects of early pregnancy in pigs, aimed to identify determinants of the high level of embryonic mortality which occurs prior to implantation

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Thesis (Ph. D.)--University of Alberta, 2009. / Title from pdf file main screen (viewed on Sept. 3, 2009). "A thesis submitted to the Faculty of Graduate Studies and Research in partial fulfillment of the requirements for the degree of Doctor of Philosophy in Animal Science, Department of Agricultural, Food and Nutritional Science, University of Alberta." Includes bibliographical references.

Thesis (Ph. D.)--University of Wisconsin--Madison, 1966. / Typescript. "Effect of estradiol-17[beta] on follicular development and pituitary potency in gilts fed 6-methyl-17-acetoxyprogesterone [by] R.L. Kirkpatrick, N.L. First and L.E. Casida, reprinted from Journal of animal science": inserted between leaves 99 and 100. Vita. Includes bibliographical references.

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