Thesis (M.S.)--Missouri University of Science and Technology, 2008. / Vita. The entire thesis text is included in file. Title from title screen of thesis/dissertation PDF file (viewed January 22, 2009) Includes bibliographical references (p. 30-34).

Thesis (M.S.)--University of Missouri-Columbia, 2004. / Typescript. Includes bibliographical references (leaves 126-137). Also available on the Internet.

The entire thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file; a non-technical public abstract appears in the public.pdf file. Title from PDF of title page (University of Missouri--Columbia, viewed on Oct. 6, 2009). Thesis advisor: Dr. Azlin Mustapha. Includes bibliographical references.

Thesis (M.S.)--University of Missouri-Columbia, 2004. / Typescript. Includes bibliographical references (leaves 126-137). Also available on the Internet.

Thesis (M.Ch.E.)--University of Delaware, 2008. / Principal faculty advisor: Richard P. Wool, Dept. of Chemical Engineering. Includes bibliographical references.

With obesity and type 2 diabetes on the rise, research is trying to find ways to reverse or slow its progress. Soy diets have been shown to be effective in doing so but have variable results. One variable that may affect soy's effectiveness is intestinal microflora. This experiment used female Zucker Diabetic Fatty (ZDF) rats that develop type 2 diabetes when fed high-fat diet and is similar to that of human development of type 2 diabetes. This study used soy diets designed to modify intestinal bacteria with probiotics or prebiotics: control, 2.5% fructooligosaccharide (FOS), 2.5% B. lactis, or 2.5% L. acidophilus. Food intake, body weight, and glucose levels were evaluated weekly throughout the study. At the end of a 23 day period total body lipids were assessed, as well as, glucose levels. The percent body lipids in the B. lactis group were higher than all other groups (p>0.05). The B. lactis and L. acidophilus groups had seemingly higher glucose levels; however, the statistical analysis was insignificant due to high variation between groups. Urine samples showed B. lactis and L. acidophilus groups had three rats with glucose levels of 500 mg/dl or above while control and FOS groups had one rat each in this category. This study showed no improvement to obesity and diabetic parameters through the microflora modifications used. In fact, some parameters worsened indicating a need for continuing research of soy with intestinal microflora modification.

Made available in DSpace on 2014-06-11T19:23:11Z (GMT). No. of bitstreams: 0 Previous issue date: 2006-11-14Bitstream added on 2014-06-13T18:09:30Z : No. of bitstreams: 1 pavanjunior_a_me_jabo.pdf: 2349645 bytes, checksum: 83da7cda8650f6c2477543560b177da6 (MD5) / Agrofito / O sistema plantio direto preconiza maior conservação dos recursos naturais, seu sucesso está diretamente relacionado ao desempenho de semeadorasadubadoras. Isto é dependente da eficiência de seus componentes em trabalhar em condições adversas, ou seja, solo com maior resistência e presença de palhada. Diante deste contexto, desenvolveu-se o presente trabalho com a cultura da soja sobre palhada de mucuna cinza e feijão guandu. O mesmo teve como objetivo avaliar o desenvolvimento na cultura da soja e o desempenho de uma semeadora-adubadora para sistema plantio direto. Os fatores estudados foram três manejos das culturas de cobertura, escolhidos em função do tamanho de fragmentação da vegetação, ou seja, triturador de palhas (palha totalmente triturada), roçadora (palha parcialmente picada) e rolo-facas (palha praticamente inteira), combinados com três velocidades do conjunto trator-semeadora-adubadora, sendo 4,0; 5,0 e 6,0 km.h-1. Durante o decorrer do experimento foram avaliados as seguintes variáveis: a) na planta: estande inicial e final, índice e sobrevivência, distribuição longitudinal de plântulas (espaçamentos normais, falhos e duplos) e produtividade de grãos; b) na máquina: capacidade de campo efetiva, força de tração e potência na barra, consumo horário e por área e combustível e patinagem dos roldanos do trator. O delineamento experimental foi em blocos casualizados em esquema fatorial 3 x 3, com nove tratamentos e oito repetições, totalizando 72 observações. As características agronômicas da cultura da soja e o desempenho da semeadora-adubadora não foram influenciados pelos três manejos na cultura de cobertura vegetal. O aumento da velocidade provocou diminuição da profundidade e conseqüente diminuição da força de tração , o inverso ocorreu com a capacidade de campo efetiva e a potência na barra... / The no tillage system preconizes a greater conservation of the natural resources, and its success is directly related to the sowing-fertilizing machines performance. It depends on the efficiency of its components in working in adverse conditions, such as a solo with a greater resistance and fodder presence. Facing this context, this present work was developed with the soy culture on gray-mucuna fodder and pigeon pea bean. The same aimed to evaluate the development in the soy culture and the sowing-fertilizing machine performance for the no tillage system. The studied factors were three covering-culture managements, chosen according to the fragmentation size of the vegetation, such as straw triturator (straw totally triturated), weeder (straw partially chopped) and knife-rolls (straw practically entire), combined with three speeds of the sowing-fertilizing-tractor set, being 4,0; 5,0 and 6,0 km.h-1. In the course of the experiment the following variants were evaluated: a) in the plant: initial and final situation, survival index, longitudinal distribution of the plantules (normal, defective and double spacing) and grain productivity; b) in the machine: effective field capacity, tensile force and power in the bar, hourly consumption for area and fuel and tractor s pulleys sliding. The experimental outlining was carried out in casual blocks in factorial scheme 3X3, with nine treatments and eight repetitions, totalizing 72 observations. The data reached were tabulated and submitted to factorial variant analysis. When the value of the F test was significant at 0, 05 of probability, the Tukey test was carried out to compare the averages. The soy culture agronomic features and the sowing-fertilizing machine performance were not influenced by the three managements in the vegetal covering culture...(Complete abstract, acess udermentioned eletronic adress)

La production de semences très vigoureuses est un levier clépour augmenter les rendements agricoles. Chez le soja, lesrisques de production de semences de faible vigueur germinativesont élevés sous les climats tropicaux, ce qui conduit àune mauvaise installation de la culture, voire un déclassementdes lots en grain. La longévité (c-a-d la capacité de survivre àl’état sec pendant de longues périodes) représente une caractéristiqueimportante de la vigueur germinative. Cependant,la façon dont elle est acquise au cours de la maturation dela graine n’est pas connue. L’objectif de la thèse était d’obtenirun aperçu des mécanismes de régulation de l’acquisitionde la longévité chez le soja. Celle-ci est acquise peu aprèsla phase de remplissage et l’acquisition de la tolérance à ladessiccation (stade R7.2) et continue d’augmenter jusqu’enfi n de maturation. Des différences de longévité ont été observéesentre les récoltes 2013 et 2014.Elles seraient liées auxtempératures élevées au cours de la formation des graines,un facteur connu pour impacter la qualité des semences. Leséquençage Illumina de graines récoltées à 7 stades de développementa révélé des changements complexes se produisantau niveau transcriptionnel dès le stade R7.2, pourtantconsidéré comme correspondant à la maturité physiologique.Les analyses d’enrichissement GO ont révélé une associationpositive entre longévité et les processus de maturation desARN et régulateurs de la post-transcription et une associationnégative avec les processus liés à la photosynthèse. L’acquisi / Soybean is one of the most important oil crop species usedfor food and feed as well as a range of industrial applications.However, producing highly vigorous seeds is a key leverto increase crop production effi ciency. Low physiologicalseed quality, which is more prone to occur under tropicalenvironment, leads to poor stand establishment and decreasedin yields. Seed longevity is the ability to survive the dry statefor prolonged periods of time and represents an importanttrait for seed quality. Here, the objective was to obtain insightsinto the mechanisms regulating the progressive acquisitionof longevity. Using Illumina high-throughput sequencing,RNA was sequenced from seven different stages duringthe acquisition of longevity, generating between 14 and 38million of reads.These reads were aligned to the Glycine maxWm82.a2.v1 gene model. Differentially expressed transcripts(DET) were correlated with the increase in seed longevity.Transcriptome and GO enrichment analyses of these DETrevealed a signifi cant over-representation of terms associatedwith response to stress and RNA processing and modifi cation.Photosynthesis biological process was related to low seedlongevity. HSF and several TF associated with biotic defense(WRKY3 and NLFX1) are candidate genes whose putative rolein seed longevity deserve further characterization. We alsoperformed the determination of the content of non-reducingsoluble sugars, and we observed that the accumulation ofnon-reducing soluble sugars are related to acquisition oflongevity but only the a

The effects of the fenretinide and genistein as single or combined drugs on ovarian cancer proliferation and viability were investigated. Hypothesis: Co-treatment with genistein will enable a lower dose of fenretinide to be effective in inhibiting the proliferation and survival of ovarian cancer cells. Methods: Low and high doses of genistein and fenretinide were tested on A2780s and A2780cp cells using trypan blue viable cell count, MTS assay. Results and conclusions: Unlike low doses of fenretinide, genistein had anti-proliferative effects on both cell lines. There were no additive or synergistic effects of the two compounds. Higher dose treatments induced anti-proliferative effects and apoptotic cell death in both A2780s and A2780cp cells, with a greater sensitivity of A2780s cells to both test compounds. Overall Conclusion: Genistein and higher doses of fenretinide similarly impair cell cycle progression and induce apoptosis. The anti-proliferative effects of genistein can be affected by co-treatment with fenretinide

Soy based products are growing in popularity in food supplementation, and a larger population of the world is consuming soy on a regular basis. Soy contains phytoestrogens, plant based mimics of the hormone estrogen. Estrogen has many functions in humans, but one relatively unexplored function is its ability to regulate the levels of the hormone oxytocin (OT) and its receptor (OTR) in the brain. OT is a hormone traditionally known for its role in birth, but recently has been as a key regulator in many different behaviors. These behaviors that OT may affect include increased maternal behaviors, increased sexual behaviors, increased social interactions, increased trust, decreased anxiety, and increased potential for pair bonding. Key phytoestrogens found in soy are of the isoflavone family, and genistein and diadzein are the main two isoflavones that have been shown to exert physiologic effects when ingested by binding to estrogen receptors in the brain. The isoflavones can be estrogen agonists or estrogen antagonists, based on the preexisting, endogenous levels of estrogen in the individual. For men and postmenopausal women, it is believed that ingesting soy can cause an increase in production of OT and OTR, resulting in an increased in OT driven behaviors. For premenopausal women, there is a high endogenous level of estrogen present, so the ingested soy can cause a decrease in production of OT and OTR in the brain, resulting in a decrease in OT driven behaviors. While there is strong evidence to suggest that this may in fact occur in humans, more human based studies, rather than animal models, must be conducted to further verify and validate this hypothesis. An important area yet unexplored is the onset and duration of these OT driven behaviors. It is unclear if these are transient, or more long lasting effects, and future studies must be done to answer this question. This area of research is certainly more relevant as soy based diets are becoming more common; moving forward additional research is needed to determine the extent of oxytocin's ability to alter behaviors in individuals in a significant way.