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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
1

Single-Step Analysis of Metabolites by Capillary Electrophoresis Using On-Line Sample Preconcentration with Chemical Derivatization

Ptolemy, Adam S. 07 1900 (has links)
New strategies for integrating sample pretreatment with chemical analyses under a single format is required for rapid, sensitive and enantioselective analyses of low abundance metabolites in complex biological samples. Capillary electrophoresis (CE) offers a unique environment for controlling analyte/reagent band dispersion and electromigration properties using a discontinuous electrolyte system allowing for highly efficient separations to be achieved. A fundamental study of the thermodynamic and electrokinetic parameters influencing enantioselectivity in chiral CE separation is first examined. A new strategy for single-step analysis of low abundance metabolites via online sample preconcentration with chemical derivatization by CE (SPCD-CE) is then detailed within. In-capillary sample preconcentration serves to enhance concentration sensitivity via electrokinetic focusing of long sample injection volumes for lower detection limits, whereas chemical derivatization by zone passing of single or multiple reagents is used to expand detectability and selectivity, notably for enantiomeric resolution of metabolites lacking intrinsic chromophores. Together, on-line SPCD-CE can provide over a 100-fold improvement in concentration sensitivity, shorter total analysis times, reduced sample handling and improved reliability for a variety of biologically relevant amino acid and amino sugar metabolites, which is also amenable to automated high-throughput screening. The basic method development and optimization parameters relevant to SPCD-CE, including applications to bacterial metabolite flux and biomarker analyses are discussed. Insight into the mechanism of analyte focusing and labelling during electromigration by SPCD-CE is also presented, as well as future directions for continued research using this unique integrated analytical platform. / Thesis / Doctor of Philosophy (PhD)
2

Strategické řízení a jeho uplatnění ve vybraném podniku / Strategical management and its use in the selected enterprise

LINHA, Jiří January 2012 (has links)
Main goal of my thesis is evaluation of strategical management at examined enterprise and suggest a strategy for its future activity on a market with barreled water based on acquired findings. Theoretical part is dedicated to basic terms and selected analyses from area of strategical management. Practical part contains STEP analysis, Porter's model, analysis of results in particular functional areas, SWOT analysis applied to the chosen enterprise. Closing part of my thesis is dedicated to evaluation of present state of the enterprise and recommendation which steps should the enterprise take to gain a better competitive position on the market.
3

Marketingová strategie pro firmu OHL ŽS, a.s. / Marketing strategy for company OHL ŽS, Inc.

Peterková, Eva January 2008 (has links)
Master´s thesis describes current economic state of the OHL ŽS, a.s., analyzes the makronomics and mikronomics surrounding. On the basis of this analysis I suggest arrangements that will lead to achieve the required marketing´s targets.
4

Analýza sortimentu EVONA a.s. / Analysis of EVONA a.s. product range

Švadlenková, Veronika January 2011 (has links)
This master's thesis is focused on analysis of EVONA a.s. product range, which is manufacturing company. Aim of this study is to analyze the range of underwear, thermal underwear and hosiery and then to propose optimization measures. The theoretical part is devoted to methods which focus on analyzing the marketing environment and product mix. In the practical part, internal company data of EVONA a.s. served to analyze the product range by using Boston Consulting Group matrix and General Electric Business matrix. To illustrate the situation a survey was carried out and it helped in the final recommendations of the product range.
5

Analýza vnějího prostředí vybraného podniku / Analysis of external environment of selected firm

HOŘEJŠÍ, Ladislav January 2010 (has links)
Assessment of the current situation and status of the selected company in the market through analysis of the external environment. Based on the results of corporate strategy and propose measures for successful management of company.
6

Analýza vnějšího prostředí vybraného podniku / Analysis of External Enviroment of Chosen Company

ŠANDOR, Pavel January 2008 (has links)
The aim of this diploma thesis is to elaborate an analysis of the external environment of a chosen company on bases of a special literature, own pieces of knowledge and gained information about the market. I have reached the results by the help of the Step analysis, the Porter{\crq}s model, the Competition analysis and the SWOT analysis. By the help of the Step analysis I tried to define factors that could influence the company even though they are outside the enterprise. On bases of the Porter{\crq}s model I have analyzed five competitive forces that influence our company namely new competitors, suppliers, customers, substitutes and a competition ring. By the help of the Competition analysis I have reviewed which companies concerned with the metal production and locksmithery are direct competitors of the company. Through the SWOT analysis method I tried to define inner strong and weak points and external opportunities and jeopardy. I have found convenient factors afterwards I have determined their importance by the help of the method of the Geminate comparison. In conclusion I have evaluated data. On their bases I have drawn up recommendations for the future development and I have suggested convenient strategies. Those strategies were strategy of the Market Development, Market Penetration, Concentric Diversification and strategy of Creation of the competitive advantage.
7

Návrh strategického plánu Asociace hráčů ledního hokeje / Ice Hockey Player's Association Strategic Plan Project

Ton, Martin January 2012 (has links)
Thesis name: Ice Hockey Players' Association strategic plan project Thesis aims: The main aim is to describe both external and internal environmental forces of Ice Hockey Players' Association and to design a complex strategic plan project for a specific time period 1.8.2012 - 31.7.2015. Methods: Supportive analytical methods SWOT and STEP were used as a descriptive analysis for identifying the initial situation of the organisation. Within the bounds of the descriptive analysis, focus group, and interview were used. Results: The outcome of this thesis is a complex project of Ice Hockey Players' Association strategic plan based on results of used analyses. Keywords: Players' association, Ice hockey, Strategic plan, SWOT analysis, STEP analysis, Non-profit organization.
8

Strategické rozhodování v obchodní společnosti / Strategic decisions in a company

VEJVODOVÁ, Klára January 2016 (has links)
The main goals of the thesis were to prepare an analysis of activities of strategic management, to improve the synergy between strategic and operational management, to enhance the quality of strategic decisions in selected company. The first step was to study and comparison of Czech and foreign professional literature and make literary summary that gives the reader into the issue of strategic management. The practical part is performed by first analysis of the current state of strategic and operational management in selected company through the following analyzes: STEP analysis, industry analysis, financial analysis, guided interview with the director of the company. Based on the results of previous analyzes were determined strengths and weaknesses and the opportunities and threats of the company. Their influence is compared in the SWOT analysis. The last part presents proposals for measures that would lead to improving the coordination of strategic and operational management and an overall improvement in key areas of the company.
9

Konflikty při využívání vodní nádrže Orlík rekreačními aktivitami / Conflicts among recreational uses of the dam Orlík

RÓKOVÁ, Lucie January 2008 (has links)
The main target of the thesis was to elaborate a project documentation that would focus on the solution of the conflicts caused by the recreational exploitation of the area. However, the results of preceding bachelor thesis (guestioning of visitors and situation analysis), interviews and of SWOT, PEST analyses pointed to the existence of several conflict issues. Based upon the current situation of the area, strategic targets, measures and tourism development plan were presented. The plan itself then offers an overview of the solutions and decisions that should contribute to the coordinated tourism development in the area. Presented project is dealing with the issue of insufficient quality of tourism infrastructure and it covers campsite reconstruction.
10

Analýza dovozu zboží vyráběného v Číně prostřednictvím spolupráce Joint Venture / Analysis of import demands from China and cooperative Joint Venture

LANGWEILOVÁ, Iva January 2013 (has links)
The main goal of the diploma thesis is to find out how the import substeps from China participate in making a price. The import substeps of products classified within the section 7 of the Standard international trade classification are analyzed. Another goal of the thesis is to discover advantages and disadvantages of JV co-operation established in China. The results of partial analyses become the basis of making guidelines for those, who are planning to establish this kind of co-operation in chinese region.

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