The purpose of this thesis is to evaluate and compare the retrieval effectiveness of two search engines on the Internet: Svensk Medicin and Google Scholar. Svensk Medicin is a medicine-specific search engine and Google Scholar specialises in indexing scholarly material. A set of 20 questions in four categories were used to conduct the searches with the search engines. Genuine medical information needs were selected from a question collection provided by the television program Fråga doktorn. The relevance of the first 10 retrieved documents was judged by using a binary scale and the measure used was precision. An analysis on average precision for all the search questions and an average measure was calculated (macro precision). Results for average precision over all the search questions and a mean average precision is also presented (micro precision and map). These measures shows which search engine performs best for single queries and how the relevant documents spread among the displayed results. The occurrence of duplicates and error pages was noted, because they also show how the search engine performs. Svensk Medicin is performing better than Google Scholar on the single queries and Svensk Medicin also retrieves the highest number of relevant documents. Methodology is discussed close since the experimental design affects the result. / Uppsatsnivå: D