Oppgaven presenterer teknikker og implementasjon for sammenlikning av naboskap av proteiner i protein-protein interaksjons-nettverk.

Today, user interfaces normally consist of a screen, and a pointing device and a keyboard for input. However, as more advanced technology and methods appears, there should be good chances to utilize these for more natural and effective human-computer interfaces. The main motivation is to get a more natural and easy to use interface, and the computer should understand the user without too much effort from the user. Intelligent interfaces could be a solution to achieve this goal. The main focus in this thesis, is multimodal input which combines different input modalities to achieve the user's goal. A framework has been designed where the user has the possibility to change between input modalities. The system should integrate the information given in different input modalities to one joint meaning. In this architecture, input could either be location or command input, and different modalities could be used for each input type. The example described later on in this thesis combines either speech or written text as command input, with either map input or physical position for location input. An agent-based blackboard architecture are used for collecting input. Agents collect information directly from the user. Each agent represent their own input modality, and is responsible to analyse input. As this is done, the agent send the information to a common blackboard which hold the latest information from each agent. An own agent which is responsible for fusing this information to one common meaning, collects the information from the blackboard and integrate it to one joint meaning. This joint interpretation decides what should be done to which object. Since the modalities are independent of each other, other modalities could easily be added with just small changes to other parts of the system as long as it is an command or location input which agrees to the currently representation structure.

This thesis is a study of how to design and introduce computer support in co-present collaborative creativity. Creativity is an important skill in today’s knowledge based society. There has been an increased focus on computer support for creativity, but a shift from individual to collaborative creativity demands a new set of frameworks and requirements for designing suitable tools. Evolving technologies in the merge of computer support for cooperateive work (CSCW), ubiquitous computing and mobile technologies have shown promising results and relevance in collaborative and creative work. This thesis is a study of how such technologies can support co-present collaborative creativity. The objective is to identify elements and structures constituting co-present collaborative creativity in order to define a set of requirements and implications for designing computer based tools. The contributions of the thesis is: 1.A conceptual framework describing elements, stuctures and general patterns in co-present collaborative creativity 2.A guideline describing requirements and implications for the design and introduction of computer based tools, including a description of which tasks can be supported and scenarios showing how. The thesis is both theoretically and empirically based. The theoretical base includes theoretical views and research within the creative domain and related work in the field of computer support for creative work. The empirical evaluation includes a case study of Oasen, an idea laboratory at the Norwegian University of Science and Technology (NTNU). The framework and the guideline presented as the results of the thesis are generalized based on a comparison of empirical results with findings in related work.

This thesis was written by Stein Eldar Johnsen beginning 15th August 2003 and delivered by 1st September 2005 with Svein Erik Bratsberg as mentor. The main topics are consistency and distributed hash tables. One unsolved problem with distributed hash tables is consistent lookup. Various DHTs can show acceptable consistency ratings, but no DHT can show no lookup inconsistency during churn. We chose to use a structural prevention strategy to remove inconsistent lookup on the basis that inconsistent lookups are a result of inconsistency in routing tables. We define consistent lookup as a lookup that returns a correct membership state from some time during lookup. Churn and especially unplanned membership changes may cause series of inconsistency problems if not handled carefully. The combination of a planned membership change (e.g. join) and an unplanned membership change (e.g. node crash causing a node to leave) can cause problems needing careful repairing in the systems routing tables. Table changes are necessary done in an order that guarantees a consistent view over index ownership, and makes the possibility of consistent termination at any point during execution. Other novel solutions include fail-fast disconnected-detection, locking membership protocols and pre-join knowledge propagation. All these solutions are shown to improve consistency through analysis, and are easily adapted for ring geometry DHTs. Accord was design to test many of the proposals made in the analysis. We built a distributed hash table infrastructure (with no hash table functionality), that used membership protocols based on the analysis results. The two main membership protocols were based on a 2-level 2-phase commit protocol for join, and simple 2-phase commit with distributed operations from a single coordinator for the leave protocol. The solutions proposed in this thesis are fit for all ring geometry DHTs, and some may be adapted for tree geometry DHTs, and some for all DHTs. All of Chord, Bamboo andPastry are good DHTs that can be used for testing the proposals, where all or most solutions are shown to be possible. Future work includes more testing, simulations and analysis of adaptations for different geometries.

This thesis have looked at two subjects that are a necessary part of a Location Based Service. Guidelines on how to make a Location Model of the campus has been suggested. The proposed model enhanced already existing suggestions and provides support for different queries. Testing was done with Ekahau WLAN positioning technology to obtain location information. The results of the testing showed that the technology was suitable to provide a services that required accuracy at room-level. Services that required a finer grained location estimate where not feasible.

Numerous standardisation and integration initiatives within the use of information and communication technologies (ICT) seem to fail due to lack of acknowledging the socio-technical negotiation that goes into standardisation work. This thesis addresses the implication of open standards development within organisational use of ICT. A standardisation initiative for data transmission, the PRODML project, within the domain of the Oil & Gas industry is investigated. This initiative strives to increase interoperability between organisations as it focus on removing the use of proprietary standards. By using Actor-Network Theory, this thesis try to articulate how such standards emerge, and the critical factors that can lead to their success. It emphasis the need to consider the importance of aligning interests in standards development, and the importance of creating the right initial alliance, building an installed base, for increased credibility and public acceptance.

The project behind this thesis empirically explored the possibility of mobile handheld devices and use situations of the hospital arena by building prototypes and have them evaluated by real users in realistic settings. The main aspects of discussion are: what characterizes work that is suitable in this context; how well does the technology support the user’s work ―input of data, output of data, navigation, ease of handling, and general usability of device; and what the ideal mobile device in a hospital would be.

This thesis focuses on the effect of nursing staff's redundant work routines on error and quality of care in one Critical Access Hospital in rural Wisconsin, USA. Methods were based on participatory design and an ethnographic approach, and included individual interviews and observation-based interviews. Introduction of a computerized information system was scheduled for the case study site and this thesis makes pre-implementation suggestions regarding staff training, interface features desired by the future users, and removal or restructuring of certain redundancies. The contribution of this thesis to information systems research is a classification system for determining the degree of redundancy (productive, gray-zone, and unproductive) present in the task chains of specific work routines, and a second classification system for determining to what extent modifying or removing an unproductive redundancy returns value. The degree to which an unproductive redundancy may be modified or removed is weighted against the difficulty of changing the work routines associated with that redundancy as well as the expected impact on other routines.

This thesis concerns the safety in user interfaces. In particular it concerns the user interfaces in systems in which safety is critical. I have studied such systems in the maritime industry, where we for instance may find them on the bridges of ships. Computer systems get more and more important in the daily routines of humans, and it is important that this does not go unnoticed. Designers of computer systems need to take human factors into consideration when designing their systems. These considerations might be especially important in complex systems, as these are often safety critical. The bridges on ships are likely to include complex systems for the operator to handle, as they often involve multiple screens, or other factors that increase the complexity of a system. Such factors might include being able to pay attention to several incidents at once. When dealing with complex systems, it is important that the operator knows how to handle the system, and also how to react when an incident occurs. These are factors that need to be considered by the designer when making the system and theories on how to do this are described in the thesis. I have also described standards which consider this, like the ISO 11064 standard, or the Atomos regulation and the ISO 17894 which considers this for the maritime industry in particular. Parts of the industry have made an effort to develop tools to be used to improve the safety. I have studied some of these efforts and presented them in the thesis. Furthermore, I have developed a survey to study how the individual members and different parts of the industry feel and behave towards safety. The survey gave an insight into reality of how safety is being handled in the industry as a whole. In particular it pointed to the main problem of the maritime industry, that the industry is very heterogeneous, and also that the different parts of the industry are in competition with each other. Most of the respondents had not heard about the Atomos regulation or the ISO 17894 standards, efforts that could have been used as a tool to improve the level of safety. The questionnaire also showed that while most of the respondents are satisfied with the level of safety in their organization, they are not satisfied with the level of safety in the overall industry. The thesis consists of six parts. Part I deals with the introduction and general theory from research methods and psychology. Part II deals with usability and related standards. These include ISO 11064, theory on usability and a description of an accident due to poorly designed user interface. Part III describes relevant background from the maritime industry, which involves the ISO 17894 standard, the Atomos regulation and e-navigation, an example of a newly made effort. Part IV gives a description of the development of my questionnaire, and also provides the results and conclusions made from them. Part V provides the conclusions and suggestions for future work, while part VI contains appendices.

Exception handling suffers from a fluke in its evolution. Some time in the 1970's, a researcher called Goodenough introduced the exception handling mechanism, known today as the tcode{try...catch} construct. At about the same time, two fellows called Parnas and Würges published a paper about "undesired events". This paper appears forgotten. The funny thing is, Parnas and Würges effectively described how to emph{use} exception handling mechanisms. There is a need to respond to this undesired event. Exception handling suffers from lack of design guidelines and a number of inconsistencies with the object-oriented paradigm, among other things. The thesis' main contribution is creating a library of exception challenges and the evaluation of safety facades, an approach that introduce an architecture and guidelines for designing exception handling. Through qualitative evaluation, this thesis shows how safety facades form an interesting new approach to exception handling.