Effect of Ankle and Foot joints mobilization on Stability improvement, analyzed by Computerized Dynamic Posturography. The aim of the study was to observe if joint mobilization of ankle and foot joints would improve the stability using the by Computerized Dynamic Posturography (neurocom) as a measurement tool. The methods that are used from the research are based on the knowledge which was obtained during the study of physiotherapy program at FTVS UK. All the participants are between the ages of 20 to 30 years, with no specific diagnose. All the 40 participants were being randomly divide into 2 groups. The control group and the experimental group, each group will have their Stability tested twice on the CPD (NeuroCom). The control group will be measured first, and after 20 minutes they will be measured again without any examination or therapeutic intervention. The experimental group was measured twice, first before the examination of joint play and the therapy, then the examination of joint play was done and any restricted joints were noted and treated, later, the participants were measured again for possible improvement. Joint play examination and therapy take about 20 minutes. Stability analyses take about 20 minutes too. The project doesn't include subjects with severe lower extremity injuries (eg,...

Gluten sensitive entheropathy - celiac disease is a lifelong, genetically predisposed, immunologically mediated susceptibility to dietary wheat gluten, most frequently demonstrated by small-bowel damage and malabsorption syndrome. Strict adherence to gluten-free diet is the sole rational therapy of the disease. One of the possible therapeutic strategy for the treating of celiac disease is to utilize the synthetic polymer P(HEMA-co-SS). This polymer is capable specifically bound gliadin in gastrointestinal tract and by this way to neutralize the damaging effect of this alimentary protein on mucosa of small intestine in celiac patients. The in vitro study on human PBMC and specimens of small intestinal biopsies of celiac patients in our laboratory demonstrated that putative therapeutic ability of P(HEMA-co-SS) is substantially influenced by degree of proteolytic processing of gliadin and P(HEMA- co-SS) and also by different timing of per os administration of both components in organism. Another putative adjuvant therapy of celiac disease is employing of the beneficial probiotic bacterial strains. Our experiments were based on the findings of Prof. Y Sánz and her group demonstrating the significant differences in the composition of bacterial microflora in patients with active form of celiac disease,...

The aim of this Theses was to investigate the effect of play therapy on children whose parents are either divorced or divorcing. This study is qualitative, adopting a casuistic approach. In the theoretical part, the stages of divorce, child's adaptation to divorce and individual non- directive play therapy are described. The practical part consists of five case studies showing practical application of play therapy. The analysis is based on ten cases (children aged three to nine years, four boys and six girls). Data were analyzed using open, axial and selective coding. Play therapy for children in divorce situations is an appropriate therapy tool for children whose both parents agree with the treatment and the child meets the indications. Children respond positively to play therapy, they express the family conflict. The results of the study open possibility for further research in the field of non-directive play therapy. Key words: play therapy, non-directive individual play therapy, divorce, adaptation to divorce

This paper gives the summary of the six-year operations of multi-family therapy programme in eating disorders at The Eating Disorders Centre at The Psychiatric Clinic, Prague. The research done has been the first experience with multi-family treatment of psychiatric patients in the Czech Republic. This therapy concept is often used abroad as a form of work with patients suffering from the diagnosis of eating disorders. It is a "first choice" method due to NICE Guideline(2004). The inspiration for the Prague team was the London Maudsley model. The main aims of the research were: 1/ to introduce this therapeutic approach into a complex treatment of patients suffering from eating disorders, optimize the functioning structure and programme and stabilize the therapeutic team and 2/ to evaluate the effectiveness of multi-family treatment and suggest the suitable metodology. Since 2004 twenty families which form the observed group have been involved in the project. The combination of qualitative and quantitative methodology was chosen during the primary stage of the research. The methods used were: questionnaires of Beck Depression Inventory (BDI),Schwartz scale of therapy assessment (SOS-10), the life quality questionnaire (SQUALA) and Rosenberg self-concept questionnaire (RSE). We evaluated ten...

Myelodysplastic syndromes (MDS) represent a group of clonal stem cell disorders characterized by ineffective hematopoiesis, peripheral cytopenia, morphological dysplasia and the risk of transformation to acute myeloid leukemia (AML). MDS belongs to one of the most common hematological diseases in patients over 60 years old. MDS incidence is still increasing. Appropriate therapy of MDS remains challenging. There is no curative approach besides peripheral stem cells transplantation, which is regretfully appropriate only for a small group of patients due to a higher median age of the MDS population. This is why the search for therapeutic alternatives remains paramount. MDS treatment was rather frustrating until the recent introduction of two new therapeutic approaches: immunomodulation therapy with lenalidomide and epigenetic or demethylating therapy with 5-azacytidine. Both new drugs have significantly higher effect than standard therapy. However, the precise mechanism of this effect remains unknown. As a result, we decided to initiate several research projects while introducing this promising treatment to our patients. Our aim is to investigate the mechanism of both agents in relation to disease pathogenesis by examining changes of certain occurrences and factors prior to and during the course of...

Myelodysplastic syndromes (MDS) represent a group of clonal stem cell disorders characterized by ineffective hematopoiesis, peripheral cytopenia, morphological dysplasia and the risk of transformation to acute myeloid leukemia (AML). MDS belongs to one of the most common hematological diseases in patients over 60 years old. MDS incidence is still increasing. Appropriate therapy of MDS remains challenging. There is no curative approach besides peripheral stem cells transplantation, which is regretfully appropriate only for a small group of patients due to a higher median age of the MDS population. This is why the search for therapeutic alternatives remains paramount. MDS treatment was rather frustrating until the recent introduction of two new therapeutic approaches: immunomodulation therapy with lenalidomide and epigenetic or demethylating therapy with 5-azacytidine. Both new drugs have significantly higher effect than standard therapy. However, the precise mechanism of this effect remains unknown. As a result, we decided to initiate several research projects while introducing this promising treatment to our patients. Our aim is to investigate the mechanism of both agents in relation to disease pathogenesis by examining changes of certain occurrences and factors prior to and during the course of...

This paper gives the summary of the six-year operations of multi-family therapy programme in eating disorders at The Eating Disorders Centre at The Psychiatric Clinic, Prague. The research done has been the first experience with multi-family treatment of psychiatric patients in the Czech Republic. This therapy concept is often used abroad as a form of work with patients suffering from the diagnosis of eating disorders. It is a "first choice" method due to NICE Guideline(2004). The inspiration for the Prague team was the London Maudsley model. The main aims of the research were: 1/ to introduce this therapeutic approach into a complex treatment of patients suffering from eating disorders, optimize the functioning structure and programme and stabilize the therapeutic team and 2/ to evaluate the effectiveness of multi-family treatment and suggest the suitable metodology. Since 2004 twenty families which form the observed group have been involved in the project. The combination of qualitative and quantitative methodology was chosen during the primary stage of the research. The methods used were: questionnaires of Beck Depression Inventory (BDI),Schwartz scale of therapy assessment (SOS-10), the life quality questionnaire (SQUALA) and Rosenberg self-concept questionnaire (RSE). We evaluated ten...

This thesis "Speech Therapy of Children with Developmental Dysarthria" deals with dysarthria and specific therapeutic methods that can be used in the context of speech therapy for children with this specific type of communication disorder. Part of the thesis includes the complete terminological definition of dysarthria etiology, its classification, its diagnosis and a detailed treatment of therapeutic methods. This thesis also includes supplemental methods, which is important for good child developmental and positively influences child speech. The main objective is to introduce potential therapeutic methods and subsequently analyze the frequency of their use in speech therapy. This thesis can be used as inspiration for speech therapists, who will lead therapy with children who have dysarthria.

The thesis contains two parts, to bind: The first part describes the phenomenon of homelessness and homeless people in the Czech Republic, with main reference to their ambiguous definition. Characterizes the dedicated assistance to the homeless and from social work to therapeutic help. Describes the basic form of therapeutic exposure and focus, emphasizes psychotherapeutic orientations, which are suitable for a group of homeless people, with an emphasis on cognitive-behavioral therapy (CBT). The first part of the research continues, describing the organization of the St. Paul's House (DsP), which took place in the first orientation research whose aim was to determine whether CBT is the most appropriate psychotherapeutic direction in psychotherapeutic work with the homeless in the DsP, and how psychotherapy is implemented in the DsP. After the landmark research was carried out research whose aim was to find feedback, experience and opinion shelter users in the implementation of the DsP and the course of psychotherapy.

OF THE THESIS This Master's thesis is dedicated to providing a complete account and analysis of activities designed to tackle specific logopaedic difficulties associated with Parkinson's disease. The principal theoretical sections of this thesis are concerned with an in-depth overview of Parkinson's disease and hypokinetic dysarthia (a speech disorder associated with Parkinson's disease), the dynamics of working with a group of senior participants, the Parkinson Society, the place of logopaedic therapy in Society and of specific components of logopaedic therapy aimed at persons with Parkinson's disease. The practical section which follows then proposes and carefully outlines specific activities suitable for such therapy. Activities are classified by their objectives - areas they intend to exercise improve. Designs of two model lessons comprising a combination of the activities proposed in the preceding chapters are included in the final section of the thesis.