Infectious diseases such as pneumonia still pose a major global health concern. Currently, the world is facing widespread emergence of acquired bacterial resistance to antibiotics which constitute one of the chief causes of infectious diseases. The accumulation of different antibiotic resistance mechanisms within the same strains has induced the appearance of the so called “superbugs”, or “multiple-drug resistant bacteria”. Due to antibiotic resistance, attention is currently being drawn towards biologically active components isolated from plant species commonly used as herbal medicine, as they may offer a new source of antibacterial, antifungal and antiviral activities. This is the basis of this study. In this study four medicinal plants namely, Cassia abbreviata, Geranium incanum, Pelargonium hortorum and Tecoma capensis were investigated for their antimicrobial potential. In vitro antimicrobial activity using agar disc diffusion method, agar dilution method and broth microdilution plate determination of minimum inhibitory concentration (MIC), were carried out against ATCC (American Type Culture Collection) strains and clinical isolates known to cause pneumonia. Aqueous, methanol and acetone extracts from the selected plants were thus tested against strains of Streptococcus pneumoniae, Haemophilus influenzae, Staphylococcus aureus, Klebsiella pneumoniae, Pseudomonas aeruginosa, Acinetobacter baumannii, Escherichia coli and Candida albicans. The plants exhibited pronounced antimicrobial activity and were more active against Gram-positive bacteria than Gram-negative bacteria. During agar disc diffusion method, the highest inhibition zone was demonstrated by the acetone extract of P. hortorum (IZ=22mm and AI=0.73) against the reference strain of S. pneumoniae (ATCC 49619). The range of zones of inhibition in diameter across strains of S. pneumoniae and H. influenzae was 7mm to 22mm with activity index range of 0.23 to 0.74. The lowest MIC produced by medicinal plants in the study during agar disc diffusion method against S. pneumoniae and H. influenzae strains, was 2.5mg/ml. In broth microdilution plate assay, the lowest MIC demonstrated by C. abbreviata, T. capensis and P. hortorum extracts on tested bacteria was 0.031mg/ml and that of G. incanum was 0.063mg/ml. Candida albicans strains were only inhibited at 20mg/ml by the study plants. The highest activity among the individual extracts was shown by P. hortorum methanol extract which inhibited 71% of the studied bacteria. T. capensis methanol extract was the least and inhibited only 17% of the tested bacteria. The strains of Klebsiella pneumoniae showed the highest resistance to medicinal plants employed in this study. Traditional preparation of selected medicinal plants did not show any significant antimicrobial activity. Bioactive analysis of compounds on study plants was carried out using standard methods which revealed the presence of anthraquinones, flavonoids, phytosterol, saponins, tannins and triterpenoids. Comparison of the inhibitory effect of the plant extracts against some broad spectrum antibiotics revealed that the tested medicinal plants showed greater antimicrobial activity than standard antibiotics. However, there was no correlation between the antibiotic susceptibility patterns of the bacteria and the effects of the plants, signifying that plants probably function through different mechanisms. Bioautographic findings on thin-layer chromatography plate, exhibited clear zones of inhibition of bacterial growth with the Rf value range of 0.09 to 0.94. Anti-mutagenic activity was assayed by the Ames mutagenicity test in the plate-incorporation method using histidine mutants of S. typhimurium strains TA 100. The selected plant extracts at 2.5mg/ml and 5mg/ml did not induce mutagenesis in the absence of liver-metabolizing enzymes. The study results indicated that the selected plants are capable of inhibiting the growth of the studied pathogenic microorganisms to a varied degree. The leaves of G. incanum, P. hortorum, T. capensis as well as the stem bark of C. abbreviata could be novel sources of antimicrobial agents that might have broad spectrum activity. The anti-mutagenic properties of the studied medicinal plants may also provide additional health supplemental value to the other claimed therapeutic properties of the plants.

The Greater Cape Floristic Region (GCFR) of South Africa has one of the most biodiverse floras in the world. Although ecological speciation is thought to be a primary mechanism behind diversification in the GCFR, it has recently been hypothesised that non-ecological speciation may have an influential role in driving diversification in the montane “sky islands” of the GCFR, potentially resulting in cryptic species. This work seeks to test the relative importance of ecological versus non-ecological processes in powering speciation at different elevations in the GCFR, and to assess the existence of multiple, range-restricted cryptic species at high elevations. The Cape grass genus Ehrharta is an ideal system in which to investigate these processes, as it contains low-, mid-, and high-elevation lineages, with a previously documented adaptive radiation in the succulent karoo. Population-level phylogenetic analyses using targeted enrichment sequencing data show that E. rupestris and E. setacea, as currently defined, are polyphyletic, and reveal multiple distinct monophyletic lineages within the Ramosa, Rehmannii and Setacea clades of genus Ehrharta. Analysis of genotyping-by-sequencing and morphological data, together with evidence of sympatry, confirm these lineages to be distinct entities, resulting in 13 to 16 putative new species, of which several can be considered cryptic. The crown node of Ehrharta is found to have originated 28 Ma, which substantially antedates previous age estimates. Comparisons of morphological evolutionary rates, as well as rates of nonsynonymous to synonymous sequence evolution (��), provide little evidence to support the hypothesis that non-ecological processes have been more important at high elevations. Both the low- and high-elevation clades show evidence of divergent ecological selection, with the Lowlands clade exhibiting high functional trait variance, and the high-elevation Setacea clade showing subtle ecological differentiation and accelerated rates of morphological evolution and �� relative to the rest of Cape Ehrharta. It is instead suggested that diversification in the Cape Ehrharta is triggered by a combination of intrinsic and extrinsic factors unique to each clade, thus corroborating a growing body of research arguing that it is simplistic to generalise radiations as ‘adaptive’ or ‘non-adaptive’. Instead, mountain radiations require an integrated approach to untangle the subtle interaction of geographic, ecological and biological factors that drive diversification.

Magister Educationis - MEd / This study aimed to ascertain in what ways violence and crime influence the teaching and learning programme in schools in a disadvantaged community. The context is a primary school in an informal settlement in Samora Machel, Philippi, in the Cape Flats, where violence is endemic. The study shows that violence does not occur in school playgrounds and areas around the school only; classrooms are becoming common sites for violence. This study sought to establish teacher and learner experiences of violence at school, and the role of school management and parents in dealing with it, with a specific focus on school policies on discipline and how violence affects teaching and learning. The investigation also included learner behaviour during recess.

Magister Artium - MA / This study evaluates the accuracy and equivalence of translated news from English to isiXhosa version in four community radio stations, two from the Western Cape and two from the Eastern Cape. Community radio stations source their local news through interviews and eye witness accounts. They get other news-worthy stories through media releases from Government Communication and Information System (GCIS), Police stations, Municipalities, Royal houses and from the office of the president. Most of the time, media releases are written in English and they have to be translated into isiXhosa as they use a high percentage of isiXhosa as a medium of their broadcasting.

Bibliography: pages 269-280. / The focus of this thesis on African women's experiences as domestic workers results from the fact that the majority of women within the African population in Cape Town are employed in this sector of economy. Further, the African working class is in a peculiar position as a result of the strict enforcement of the Coloured Labour Preference Policy. This policy ensured the almost total exclusion of the African population from decent housing and education as well as employment. In fact, the policy has hamstrung almost every aspect of the African population's life. The Coloured Labour Preferential Policy was coupled with the strict enforcement of influx control, governed by the Urban Areas Act No. 25 of 1945 as amended. Worst hit by this law were the African women. An attempt was made to understand the experiences of African women both in and outside their work situation. The examination of their gendered experiences of 'race' and class divisions has led to the identification of a number of issues, among them poverty, exploitation as rightless workers and payment of low wages, fragmentation of family life and subordination in marriage relations, childcare problems, housing problems and isolation as mothers and workers. Further, their dreams, which include a wish for securing property, a secure family life and educating their children, as well as self-employment, are all indications of their deprivation and exploitation as women. In this thesis gender has been prioritised, as it emerged as the prime feature of African women's experiences of social divisions. Being a woman in a society divided by 'race' and class, has created hierarchies which carry unequal relationships between employer and employee and the payment of low wages. The privatised nature of this unequal relationship is the key to the oppression and exploitation of domestic workers. Moreover, the impact of the double day on African Women domestic workers has resulted in particular experiences of exploitation and oppression. Because of the limited material currently available on domestic workers, this study is seen as a contribution to the study of women as well as a contribution to a gender-sensitive, working class history of Cape Town. The selected literature that has been reviewed has left the gendered experiences of African women unexposed within their households. The focus has been on the work situation only. Failure to recognise or identify these gendered experiences within both class and 'race' divisions results in obscuring the daily struggles that African women face regarding housing, family life and childcare facilities. The review of the two commissions of enquiry, namely the Riekert and Wiehahn Commissions has shown that the State is still unresponsive to the needs of women as workers and in particular, as domestic workers. Riekert has tied the availability of housing to employment, thus excluding a large number of women in the Cape Town urban area.

MA, Faculty of Arts,University of the Witwatersrand, 1953

<p>This study analyses the challenges faced by adult educators in reducing illiteracy among adult above twenty years of age in the Eastern Cape. The focal point is on ascertaining why there is an increase in the percentage of illiteracy in the province despite a slight decrease in other provinces. Most importantly is the determination of the significant role played by adult educators. A qualitative approach is employed to pursue the aims of the study. Data is collected using semi-structured interviews. The study has shown that lack of monitoring and supervision by ABET administrators, lack of resources for skills development and language of instruction, all contribute to the increase in illiteracy rate in the Province. For administrators of adult learning programmes it is suggested that they become more familiar with operations at Adult Learning Centres and provide training including technical where appropriate. Designers of curriculum should select curriculum resources appropriate to adult learners. Providers of direct support to adult learners should ensure that training is provided on an ongoing basis. This training should focus on teaching methods and learning approaches (pedagogy) as well as the effective use of ABET learning and teaching guides.</p>

Diss. (sammanfattning) Stockholm : Karol. inst. / Härtill 6 uppsatser.

As academic libraries continue to evolve as service organizations, they should focus on their users. This calls for a better understanding of the specific needs of library users in order to provide the appropriate type and level of service that meets those needs. The overriding goal will be user satisfaction. In this study, a survey was used to determine the levels of satisfaction of post-graduate education students with library services at the University of Transkei. A questionnaire was administered to 100 post-graduate education students registered in 1998 of which 57 responded. The most important finding that emerged from the analysis of the responses was that the majority of the respondents were in general satisfied with the library services offered at UNITRA. However, dissatisfaction was expressed by at least twenty percent of respondents with noise levels, opening hours, lack of photocopiers, the accuracy of the library catalogue, materials being in their correct place, inefficient staff and interloans. It was found that respondents were reluctant to commit themselves to expressing high levels of satisfaction or dissatisfaction. Suggestions made by respondents included computerization and the need for staff training. Recommendations based on the findings were then made followed by suggestions for further research. / Thesis (M.A.)-University of Natal, Pietermaritzburg, 1999.

This study is a brief history of college libraries in the former Transkei, from 1882 (the period of the missionaries) to 1994 (the year when Transkei was reincorporated into the Republic of South Africa). The history of college libraries in the Transkei has never been fully documented, despite the fact that some of the colleges and their libraries have been in existence for some time. Besides, there were some colleges which were without libraries. Even those that existed had not been fully developed, and the reasons for this have not been articulated. The author, therefore, considered it relevant to research the development of college libraries in this region. Fourteen college libraries were examined chronologically, starting from the colleges established during the missionary period (1882-1953), to the colleges established during the period of independence (1977 -1994) . Other periods covered were those of Bantu Education (1953-1962) and self-government (1963-1976). In order to provide a framework for the study, the historical development of each of the college libraries was examined in terms of the following criteria: adequacy of library accommodation; staffing; budget; the size and type of collection; users and types of services offered. The researcher gathered data by consulting and interviewing relevant people. Both primary and secondary sources were consulted. Conclusions drawn in this study clearly show that college libraries in the former Transkei were far from being centres of teaching, learning and research. Library staff were hampered in their efforts to improve library services, not only by a lack of funds and resources but also by the lack of a clear government policy regarding college libraries and by a lack of moral support. / Thesis (M.I.S.)-University of Natal, Pietermaritzburg, 1999.