Global ETD Search

21	Studies of the prevalence and the clinical and pathological relevance of anti-bactericidal/permeability-increasing protein autoantibodies in inflammatory bowel disease and primary sclerosing cholangitis Walmsley, Russell Stuart January 2000 (has links) No description available. 610 Ulcerative colitis; Crohn's disease
22	Characterisation and study of unclassified bacteria cultured from inflammatory bowel disease tissues Loughlin, Mark January 1995 (has links) No description available. 579 Crohn's disease; Ulcerative colitis
23	Properties and pharmacological manipulation of smooth muscle of the anorectum Cook, Timothy Alan January 1999 (has links) No description available. 615.1
24	The adherent colonic mucus layer in situ Strugala, Vicki January 2000 (has links) No description available. 612 Crohn's disease; Ulcerative colitis
25	Colonic mucus in inflammatory bowel disease Rankin, B. J. January 1996 (has links) No description available. 610 Crohn's disease; Ulcerative colitis
26	An investigation of the role of tissue transglutaminase in programmed cell death (apoptosis) Thomas, Graham L. January 1998 (has links) No description available. 572 Ulcerative colitis; Wound healing
27	Adhesion molecules in the gastrointestinal tract : a search for cell surface molecules upregulated in inflammatory bowel disease Bloom, Stuart January 1993 (has links) No description available. 610 Crohn's disease; Ulcerative colitis
28	Prebiotic activity of isomalto-oligosaccharides Ketabi, Ali 06 1900 (has links) Isomalto-oligosaccharides (IMO) with α(1→6) and α(1→4) glucosidic linkages are produced by enzymatic conversion of starch. Isomalto-oligosaccharides are partially digested in the intestine but little information is available regarding their metabolim in vivo. It was the aim of this study to investigate IMO metabolism by lactobacilli and bifidobacteria and to determine the effect of IMO diet on intestinal microbiota in a rodent model, and a rodent model for inflammatory bowel disease (IBD). Different strains of bifidobacteria and lactobacilli were grown in de Man Rogosa Sharpe media with IMO as sources of carbohydrates. Substrates and metabolites of carbohydrates metabolism were analyzed. Lactobacilli metabolized isomaltose whereas isomalto-triose and higher degree of polymerisation (DP) oligosaccharides were metabolized by bifidobacteria first. To determine the modulating effects of IMO in the intestine, a group of six F344 rats were fed IMO diet for six weeks and compared to rats fed control diet. Assessment of intestinal microbiota and their metabolites was performed by PCR- denaturing gradient gel electrophoresis (PCR-DGGE), quantitative PCR (qPCR) and quantification of short chain fatty acids (SCFA). The Lactobacillus group was one of the dominant bacterial taxa in the fecal samples of rats. Isomalto-oligosaccharides selectively stimulated lactobacilli and increased their diversity in rats compared to those on control or inulin diet. The potential health benefit of IMO was evaluated in a rodent model for IBD. Three groups of HLA-B27 rats were fed IMO, fructo-oligosaccharides (FOS) or control diet for 12 weeks. The Lactobacillus group and bifidobacteria numbers were increased significantly in the fecal samples of rats fed IMO or FOS diet respectively. Numbers of Enterobacteriaceae family were significantly increased in the rats fed IMO or FOS diet compared to the control group. Clostridium coccoides group, Clostridium leptum group, Clostridium cluster XI and total number of bacteria were significantly decreased in the rats fed FOS diet compared to the rats fed control diet. Moreover, IMO and FOS diets showed a unique effect on intestinal microbiota compared to the control diet. Cecum histology scores showed a significant decrease of inflammation in the rats fed IMO or FOS diet compared to the rats fed control diet. / Food Science and Technology prebiotic Isomalto-oligosaccharides ulcerative colitis
29	Effects of heparin on 2,4-dinitrobenzene sulfonic acid-induced ulcerative colitis and ethanol-induced gastritis in rats 馮漢生, Fung, Hon-sang. January 2000 (has links) published_or_final_version / Medical Sciences / Master / Master of Medical Sciences Ulcerative colitis Gastritis Heparin. Rats.
30	Effects of zinc on 2,4-dinitrobenzene sulfonic acid-induced ulcerativecolitis in rats 陸皓開, Luk, Ho-hoi. January 2000 (has links) published_or_final_version / Medical Sciences / Master / Master of Medical Sciences Ulcerative colitis Dinitrobenzenes Zinc. Rats.

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