It has been found in previous studies that there is a correlation between the placenta regulatory genes and the weight gain of the mother, Body Mass Index (BMI) as well as the birthweight of the fetus. When the mother gains weight / is overweight, this will affect the gene expression in the placenta, and in turn this triggers the weight gain of the fetus. The aim of the study was to investigate the correlation between the lipoprotein lipase gene and the mother's BMI, weight gain and the child's birth weight by extracting RNA from the placentas and analysing its quality and concentration. cDNA was generated from RNA using reverse transcription and gene expression was amplified using real-time PCR. The data from real-time PCR was used in the comparative Ct-method to calculate a 2˄(-ΔΔCt)-value which represents the RNA-level of the LPL-gene. Lastly this value was analysed by using the two-statistic methods, Pearson's rank correlation and Spearman's correlation, which showed that the value of the correlation coefficient for all the variables was close to the value of zero. The closer the value is to zero, the weaker the association becomes between the different variables. The correlation was 0.045, 0.112 and 0.044 for the child's birth weight, mother's BMI respective weight gain. The results from this study shows that there is no correlation between LPL and the mother's weight gain, BMI, or the child's birth weight.

Introducción: La valoración del estado nutricional de las gestantes es fundamental para lograr un estado óptimo de ellas y de sus hijos. Objetivo: Determinar la relación entre la ganancia de peso gestacional y el peso del recién nacido en puérperas atendidas en el Servicio de Ginecología del Centro Médico Naval. Materiales y métodos: Estudio cuantitativo, descriptivo de tipo correlacional y transversal. La población estuvo conformada por 61 puérperas y sus recién nacidos en el Centro Médico Naval. Se trabajó con la población encontrada durante el periodo de agosto a setiembre donde se diseñó una ficha para la recolección de datos. Para el análisis estadístico se utilizaron las pruebas de Rho de Spearman y coeficiente de contingencia de Pearson. Resultados: La edad materna promedio fue de 29± 4.27 años, la mitad estaba casada con grado de instrucción superior. En índice de masa corporal pre gestacional de las puérperas fue para normal de 52.5%; sobrepeso, 41% y; obesas ,6.6%. Correspondiendo al 49% de gestantes con ganancia adecuada; mientras que la ganancia inadecuada por exceso fue del 31.1% y 19.6% a ganancia insuficiente de peso. Los recién nacidos con macrosomía representó el 4.9%. Se obtuvo correlación no significativa entre la ganancia de peso gestacional y el peso del recién nacido, según pruebas estadísticas por Spearman ρ (rho)=0.083 y por coeficiente de contingencia de Pearson (CC= 0.35). Conclusiones: No se evidenció una relación significativa entre la ganancia de peso gestacional y el peso del recién nacido. El promedio de edad fue 29.72 años, la mayoría de procedencia costeña, casadas y con grado de instrucción superior. Asimismo, se evidencio que un 49% alcanzo un peso adecuado, 20% bajo peso y 31% peso excesivo. En cuanto al recién nacido un 95.1% fueron normosómicos y un 4.9% macrosómico. / Introduction: The assessment of the nutritional status of pregnant women is essential to achieve an optimal state of them and their children. Objective: To determine the relationship between gestational weight gain and the weight of the newborn in postpartum nurses treated in the Gynecology Service of the Naval Medical Center. Materials and methods: Quantitative, descriptive, correlational and cross-sectional study. The population consisted of 61 puerperal women and their newborns at the Naval Medical Center. We worked with the population found during the period from August to September where a file for data collection was designed. For the statistical analysis, Spearman's Rho tests and Pearson's contingency coefficient were used. Results: The average maternal age was 29 ± 4.27 years, half were married with higher education. In the pre-gestational body mass index of the puerperal women, it was normal for 52.5%; overweight, 41% and; obese, 6.6%. Corresponding to 49% of pregnant women with adequate earnings; while the inadequate excess gain was 31.1% and 19.6% to insufficient weight gain. Newborns with macrosomia accounted for 4.9%. No significant correlation was obtained between gestational weight gain and newborn weight, according to statistical tests by Spearman ρ (rho) = 0.083 and by Pearson's contingency coefficient (CC = 0.35). Conclusions: There was no significant relationship between gestational weight gain and newborn weight. The average age was 29.72 years, most of them from the coast, married and with a higher education level. Likewise, it was evidenced that 49% reached an adequate weight, 20% underweight and 31% overweight. As for the newborn, 95.1% were normosomal and 4.9% macrosomic. / Trabajo de investigación