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Previous issue date: 2012-08-28 / Objective: To evaluate the association of maternal serum uric acid (UA) and
proteinuria with clinical and demographic data of pregnant women with preeclampsia
syndrome (PES) complicated by HELLP syndrome.
Methods: One hundred and nine pregnant women were divided into two groups:
group 1 - HELLP pregnant women with PES complicated by HELLP syndrome
(n=64); group 2 PES pregnant women with PES but no HELLP syndrome
(n=105).
Results: Age, ethnicity, parity, delivery mode and perinatal mortality were not
statistically different between groups. Systolic and diastolic blood pressure, protein to
creatinine (P/C) ratio, uric acid, creatinine and maternal complications were
statistically different between groups; values were higher and events, more frequent
among pregnant women with HELLP syndrome. The newborns of pregnant women
with HELLP syndrome were more premature, had a lower birth weight and a lower
APGAR score.
Conclusion: Uric acid equal to or higher than 6.0 gm/dL and P/C ratio equal to or
higher than 5 were more frequent in gestations with HELLP syndrome, which
suggests that elevated proteinuria and uric acid levels in pregnant women with PES
may increase the chances of developing HELLP syndrome / Objetivo: Avaliar a associa??o dos n?veis maternos de ?cido ?rico s?rico (AU) e protein?ria e os dados cl?nicos e demogr?ficos em gesta??es complicadas por s?ndrome de pr?-ecl?mpsia (SPE), com s?ndrome de HELLP. M?todos: Cento e sessenta e nove gestantes foram divididas em dois grupos: Grupo 1 - HELLP gestantes com SPE complicada pela s?ndrome de HELLP (n=64); Grupo 2 SPE gestantes com SPE sem s?ndrome de HELLP (n=105). Resultados: N?o ocorreram diferen?as estatisticamente significativas quanto ?s vari?veis idade, cor, paridade, via de parto e mortalidade perinatal entre os grupos. Press?o arterial sist?lica, press?o arterial diast?lica, ?ndice protein?ria/creatinin?ria (P/C), ?cido ?rico, creatinina e complica??es maternas apresentaram diferen?a estatisticamente significativa entre os dois grupos, sendo mais elevados e mais frequentes nas gestantes com s?ndrome de HELLP. Observou-se que os RN de gestantes com s?ndrome de HELLP foram mais prematuros, apresentaram menor peso ao nascimento e menor ?ndice de APGAR. Conclus?o: ?cido ?rico igual ou maior do que 6,0 mg/dL e ?ndice P/C igual ou maior do que 5 foram mais frequentes nas gesta??es com s?ndrome de HELLP, o que permite supor que maiores valores de ?cido ?rico e de protein?ria em gestantes com SPE aumentam a chance de desenvolvimento de s?ndrome de HELLP.
| Identifer | oai:union.ndltd.org:IBICT/oai:tede2.pucrs.br:tede/1708 |
| Date | 28 August 2012 |
| Creators | Cunha, Hilda Helena Souza da |
| Contributors | Antonello, Ivan Carlos Ferreira |
| Publisher | Pontif?cia Universidade Cat?lica do Rio Grande do Sul, Programa de P?s-Gradua??o em Medicina e Ci?ncias da Sa?de, PUCRS, BR, Faculdade de Medicina |
| Source Sets | IBICT Brazilian ETDs |
| Language | Portuguese |
| Detected Language | English |
| Type | info:eu-repo/semantics/publishedVersion, info:eu-repo/semantics/masterThesis |
| Format | application/pdf |
| Source | reponame:Biblioteca Digital de Teses e Dissertações da PUC_RS, instname:Pontifícia Universidade Católica do Rio Grande do Sul, instacron:PUC_RS |
| Rights | info:eu-repo/semantics/openAccess |
| Relation | 7620745074616285884, 500, 600, -8624664729441623247 |
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