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Previous issue date: 2011-08-08 / A disfun??o sexual corresponde a altera??es em uma ou mais fases da resposta sexual
humana e apresenta maior preval?ncia na popula??o feminina. Ademais, a participa??o
de alguns fatores como obesidade e n?veis dos horm?nios esteroidais na disfun??o
sexual feminina (DSF) permanece incerta. O presente estudo deteve-se na an?lise da
ocorr?ncia de DSF numa popula??o de mulheres portadoras de obesidade, cadastradas
no Ambulat?rio de Cirurgia Bari?trica do Hospital Universit?rio Onofre Lopes, da
Universidade Federal do Rio Grande do Norte, no munic?pio de Natal, RN. O estudo foi
realizado em uma amostra composta por trinta e uma mulheres, com idade entre 20 e 50
anos, com ?ndice de massa corp?rea (IMC) > 30 Kg/m2. A todas as pacientes foi
aplicado um question?rio composto por uma se??o com dados socio-econ?micos, e
outra abordando a sa?de sexual feminina, sendo esta ?ltima correspondente ao Female
Sexual Function Index (FSFI), para diagn?stico de DSF. A partir dessa caracteriza??o,
as pacientes foram reunidas nos grupos CD (pacientes com disfun??o, n= 9) e SD (sem
disfun??o, n= 22). Para a an?lise do efeito da obesidade na DSF, as pacientes foram
reunidas nos grupos 1 (6 pacientes com IMC grau I e II: entre 30 e 40 Kg/m2) e 2 (25
com IMC grau III: acima de 40). Para o estudo da participa??o dos horm?nios
esteroidais foram determinadas as concentra??es s?ricas de cortisol, estradiol e
dehidroepiandrosterona (DHEA) pelo m?todo de quimiluminesc?ncia. A an?lise
estat?stica dos dados foi realizada usando os testes ANOVA, MANOVA (Pillai), al?m
de an?lise de Cluster. Para identificar as diferen?as entre os dom?nios do FSFI, foi
usado o teste T de Student. A signific?ncia considerada para todos os testes foi para p<
0,01. Das pacientes estudadas, 25,8% apresentaram DSF de acordo com o escore total
do FSFI. A an?lise estat?stica posterior evidenciou que as diferen?as ocorreram para os
dom?nios desejo, excita??o e orgasmo. N?o foi encontrada rela??o da presen?a de DSF
com os diferentes graus de obesidade ou com os n?veis hormonais dos ester?ides
cortisol, estradiol ou DHEA. Contudo, foi encontrado aumento significativo nos n?veis
s?ricos de estradiol para o grupo 1, que corresponde ao de menor ?ndice de IMC. Estes
resultados mostram que a preval?ncia de DSF n?o diferiu entre os graus I,II e III de
obesidade das pacientes deste estudo mas, quando presente, a disfun??o ocorre nos
dom?nios desejo, excita??o e orgasmo. A maior concentra??o de estradiol encontrada
nas pacientes de menor ?ndice de IMC sugere uma poss?vel rela??o entre as duas
vari?veis que precisa ser investigada em estudos futuros. / Sexual dysfunction corresponds to changes in one or more phases of human
sexual response and it has major prevalence in women. At the same time,
the participation of some factors such as obesity and levels of steroid
hormones in female sexual dysfunction (FSD) remains uncertain. This study
analyzed the occurrence of DSF in a population of obese women part of the Bariatric
surgery clinic at the Onofre Lopes Academic Hospital of the Federal University of Rio
Grande do Norte, Natal, RN. The study was conducted in a sample of thirty-one
women, aged between 20 and 50 years with body mass index (BMI) > 30
kg/m2. All patients answered a questionnaire consisting of two sections
addressing socioeconomic conditions and female sexual health, the latter
corresponding to the Female Sexual Function Index (FSFI) for the diagnosis
of FSD. Using this characterization the patients were divided in groups CD
(nine patients with dysfunction) and SD (twenty-two patients with no sexual
dysfunction). To analyze the effect of obesity on the DSF, the patients were
divided in groups 1 (6 patients with obesity grade I and II: BMI between 30
and 40 kg/m2) and 2 (22 patients with obesity grade III: BMI above 40). To
investigate the role of steroid hormones, serum levels were determined for
cortisol, estradiol, and dehydroepiandrosterone (DHEA), using
chemiluminescence method. The statistical analysis was performed using ANOVA,
MANOVA (Pillai) and cluster analysis. To identify the differences between the
domains of the FSFI, was used the Student t test. The significance level for all tests was
p <0.01. Of the patients studied, 25.8% had DSF according to the total FSFI
score. The statistical analysis showed that the differences occurred for the
domains desire, arousal and orgasm. No relationship was found for the
presence of DSF with different degrees of obesity and steroid hormone levels.
However, was found significant increase in estradiol serum levels for group 1,
which corresponds to the lowest BMI. These results show that the presence of FSD
did not differ between grades I, II and III of obesity in this study, but, when present,
dysfunction occurs in the domains desire, arousal and orgasm. The highest estradiol
concentration found in patients with the lowest BMI suggests a possible relationship
between the two variables, and should be investigated in future studies.
| Identifer | oai:union.ndltd.org:IBICT/oai:repositorio.ufrn.br:123456789/17323 |
| Date | 08 August 2011 |
| Creators | Carrilho, Paulo Jos? Faria |
| Contributors | CPF:06705430478, http://lattes.cnpq.br/8488760386226790, Vieira, Elisabeth Meloni, CPF:28355695615, http://lattes.cnpq.br/9432411446405065, Maranh?o, T?cia Maria de Oliveira, CPF:13049127449, http://lattes.cnpq.br/7869140767244263, Sousa, Maria Bernardete Cordeiro de |
| Publisher | Universidade Federal do Rio Grande do Norte, Programa de P?s-Gradua??o em Psicobiologia, UFRN, BR, Estudos de Comportamento; Psicologia Fisiol?gica |
| Source Sets | IBICT Brazilian ETDs |
| Language | Portuguese |
| Detected Language | English |
| Type | info:eu-repo/semantics/publishedVersion, info:eu-repo/semantics/masterThesis |
| Format | application/pdf |
| Source | reponame:Repositório Institucional da UFRN, instname:Universidade Federal do Rio Grande do Norte, instacron:UFRN |
| Rights | info:eu-repo/semantics/openAccess |
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