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Previous issue date: 2016-03-29 / Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior - CAPES / Periodontitis is the second most frequent oral disease in the world and it is defined as an infection of periodontal supporting tissues associated with bacterial biofilm accumulation on the tooth surface. The hypothesis that periodontitis is associated with systemic repercussions has drawn the attention of the scientific community, including its contribution to the development of anemia, which in pregnancy may be related to undesirable outcomes. Most cases of anemia during pregnancy can not be originally iron deficiency, but due to chronic inflammation that characterizes anemia of chronic disease (ACD). Nonetheless, the possible association between the two diseases is related to iron metabolism. This study investigated the influence of different levels of periodontitis severity in anemia of chronic disease in pregnant women. Methods: Cross-sectional study was conducted in Santo Antonio de Jesus, Bahia, Brazil, from February 2014 to January 2016. The data collection was the application of a questionnaire to obtain socioeconomic-demographic, lifestyle, health condition and related to pregnancy information, blood collection and oral assessment, with full mouth examination which included the following parameters: probing depth, clinical attachment level and bleeding on probing. Participants were classified according to the level of periodontitis severity, mild, moderate and severe, using two defining criteria. They were also classified according to the presence or absence of ACD. Association measurements between exposure and outcome were estimated using Poisson regression analysis, obtaining the prevalence ratio (PR) and confidence intervals at 95% (95% CI). Results: the final sample included 616 pregnant women, of which 16.56% (102) were diagnosed with ACD. The presence of periodontitis ranged from 16.72% to 67.53%, according to the definition criterion. There was no association between levels of periodontitis severity and ACD nor between periodontitis and ACD for both studied criteria: PRcrude = 0.60, 95% CI: [0.33 to 1.08] and PRcrude = 0.89, 95% CI: [0.76 to 1.05], even after adjustment for the following confounders: schooling level, smoking habit, age, number of prenatal consultations, parity and toothache in the last six months, PRadjusted = 0.61, 95% CI: [0.34 to 1.09] and PRadjusted = 0.90 , 95% CI: [0.76 to 1.05]. Conclusions: the findings of this research indicated that the presence of periodontitis, regardless of the severity level is not associated with the ACD, although there is a high frequency of these diseases in the studied group. Additional studies are needed to confirm these results, considering the importance of the two diseases as public health problems, as well as the relevance of the pregnancy. / A periodontite ? a segunda doen?a bucal mais frequente no mundo e ? definida como uma infec??o dos tecidos periodontais de suporte associada ao ac?mulo de biofilme bacteriano na superf?cie dent?ria. A hip?tese de que a periodontite se associa a repercuss?es sist?micas tem chamado a aten??o da comunidade cient?fica, incluindo a sua contribui??o para o desenvolvimento de anemia, que na gravidez pode estar relacionada a desfechos indesej?veis. A maioria dos casos de anemia na gesta??o pode n?o ser originalmente ferropriva, por?m decorrente de inflama??es cr?nicas, caracterizando a anemia de doen?a cr?nica (ADC), mas a possibilidade de associa??o entre as duas doen?as est? relacionada ao metabolismo do ferro. Este estudo investigou a influ?ncia dos diferentes n?veis de gravidade da periodontite na anemia de doen?a cr?nica em gestantes. M?todos: estudo transversal foi realizado em Santo Antonio de Jesus, Bahia, Brasil, entre Fevereiro de 2014 e Janeiro de 2016. A caracteriza??o da amostra foi feita a partir da aplica??o de um question?rio para obten??o de informa??es socioecon?mico-demogr?ficas, de estilo de vida e condi??es de sa?de e relacionadas ? gesta??o, coleta sangu?nea e avalia??o bucal, com o exame periodontal completo que incluiu os seguintes descritores: profundidade de sondagem, n?vel de inser??o e sangramento ? sondagem. As participantes foram classificadas segundo o n?vel de gravidade de periodontite, em leve, moderada ou grave, a partir de dois crit?rios de defini??o. Foram classificadas tamb?m quanto ? presen?a ou aus?ncia de ADC. Procedeu-se an?lise de regress?o de Poisson, obteve-se Raz?o de Preval?ncia (RP) e seus intervalos de confian?a a 95% (IC95%). Resultados: a amostra final incluiu 616 gestantes, das quais 16,56% (102) apresentaram diagn?stico de ADC. A ocorr?ncia de periodontite variou de 16,72% a 67,53%, de acordo com o crit?rio de defini??o. N?o foi encontrada associa??o entre os n?veis de gravidade de periodontite e ADC e tampouco entre periodontite e ADC, para ambos os crit?rios estudados: RPbruta = 0,60, IC95%: [0,33 ? 1,08] e RPbruta = 0,89, IC95%: [0,76 - 1,05], mesmo ap?s ajuste para os seguintes confundidores: n?vel de escolaridade, h?bito de fumar, idade, n?mero de consultas de pr?-natal, paridade e dor de dente nos ?ltimos seis meses, RPajustada = 0,61, IC95%: [0,34 ? 1,09] e RPajustada= 0,90, IC95%: [0,76 - 1,05]. Conclus?es: os achados da presente investiga??o sinalizaram que a presen?a de peridontite, independentemente do n?vel de gravidade, n?o tem associa??o com a ADC, muito embora haja altas frequ?ncias das doen?as no grupo estudado. Estudos adicionais s?o necess?rios para confirmar esses resultados, diante da import?ncia das duas enfermidades como problemas de sa?de p?blica, bem como da relev?ncia do per?odo gestacional.
| Identifer | oai:union.ndltd.org:IBICT/oai:tede2.uefs.br:8080:tede/559 |
| Date | 29 March 2016 |
| Creators | Pimenta, Rodolfo Macedo Cruz |
| Contributors | Cruz, Simone Seixas da |
| Publisher | Universidade Estadual de Feira de Santana, Mestrado Acad?mico em Sa?de Coletiva, UEFS, Brasil, DEPARTAMENTO DE SA?DE |
| Source Sets | IBICT Brazilian ETDs |
| Language | Portuguese |
| Detected Language | English |
| Type | info:eu-repo/semantics/publishedVersion, info:eu-repo/semantics/masterThesis |
| Format | application/pdf |
| Source | reponame:Biblioteca Digital de Teses e Dissertações da UEFS, instname:Universidade Estadual de Feira de Santana, instacron:UEFS |
| Rights | info:eu-repo/semantics/openAccess |
| Relation | -2122225376607208326, 600, 600, 600, 600, 1006395569471477890, -1614662311676629386, 3590462550136975366 |
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