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Previous issue date: 2013-06-06 / CAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível Superior / A total of 282 endophytic fungi were collected from these two plants, which
were classified into 19 groups according to their morphological characteristics. Of
these groups, 12 had their genus identified (Penicillium, Fusarium, Colletotrichum,
Guignardia, Phomopsis, Cephalosporium, Bionectria, Xylaria, Aspergillus, Lirula,
Pestalotiopsis and Trichoderma). Five strains (Penicillium, Fusarium, Cephalosporium,
and two Xylaria) were selected for large-scale culture, whose extracts were
fractionated. Fiveisolatedsubstanceswereidentified(austdiol19-20epoxycytochalasin
Q, cytochalasin D, 7-decloro griseofulvin and 5-methoxycarbonyl-melein), one
of which – austdiol – was produced in large quantities by a fungus of the Fusarium
genus, which is the first report of this substance being produced by a fungus of the
Hypocreales class. The endophytic fungi proved be a good source of substances with
biological activity. / Um total de 282 fungos endof´ıticos foram coletados nas duas plantas, que foram
classificados em 19 grupos, de acordo com suas caracter´ısticas morfol´ogicas. Destes,
12 grupos tiveram o gˆenero identificado (Penicillium, Fusarium, Colletotrichum,
Guignardia, Phomopsis, Cephalosporium, Bionectria, Xylaria, Aspergillus, Lirula,
Trichoderma e Pestalotiopsis). Cinco cepas (Penicillium, Fusarium, Cephalosporium,
e duas Xylaria) foram selecionadas para cultura em larga escala, cujos extratos
foram fracionados. Cinco substˆancias isoladas foram identificadas (austdiol, 1920
epoxi citocalasina Q, citocalasina D, 7-decloro griseofulvina e 5-metoxicarbonilmele´ına),
sendo que uma delas – austdiol – foi produzida em grande quantidade por
um fungo do gˆenero Fusarium, sendo esta o primeiro relato desta substˆancia sendo
produzida por um fungo da classe Hypocreales. Os fungos endof´ıticos se mostraram
uma boa fonte de substˆancias com atividade biol´ogica.
| Identifer | oai:union.ndltd.org:IBICT/oai:http://localhost:tede/4442 |
| Date | 06 June 2013 |
| Creators | Marcon, Edson Luís |
| Contributors | Souza, Afonso Duarte Leão de, Souza, Antônia Queiroz Lima de, Barison, Andersson, Pohlit, Adrian Martin, Pinheiro, Maria Lúcia Belém, Pereira, José Odair |
| Publisher | Universidade Federal do Amazonas, Programa de Pós-graduação em Química, UFAM, Brasil, Instituto de Ciências Exatas |
| Source Sets | IBICT Brazilian ETDs |
| Language | Portuguese |
| Detected Language | English |
| Type | info:eu-repo/semantics/publishedVersion, info:eu-repo/semantics/doctoralThesis |
| Format | application/pdf |
| Source | reponame:Biblioteca Digital de Teses e Dissertações da UFAM, instname:Universidade Federal do Amazonas, instacron:UFAM |
| Rights | info:eu-repo/semantics/openAccess |
| Relation | 45413454253692039, 600 |
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