Electrochemical poly(ProDOT) dendritic DNA aptamer biosensor for signalling interferon gamma (IFN-ɣ) TB biomarker

Description

Philosophiae Doctor - PhD / Tuberculosis (TB) is an infectious disease that, despite all efforts devoted towards its
eradication, remains a threat to many countries including South Africa. Current diagnostic
assays do offer better performance than the conventional sputum smear microscopy and
tuberculin skin tests. However, these assays have been proven to be affected by various factors
including the condition of an individual's immune system and vaccination history. By far,
electrochemical biosensors are amongst the currently investigated techniques to address the
shortcomings associated with these diagnostics. / 2020-08-31

Links & Downloads

1. Sidwaba, Unathi. ( 2017). Electrochemical poly(ProDOT) dendritic DNA aptamer biosensor for signalling interferon gamma (IFN-ɣ) TB biomarker. PhD. University of the Western Cape
2. http://hdl.handle.net/11394/5507

Tags

Aptasensor

Bisphenol A

Conducting polymer nanocomposites

Disease biomarker

DNA aptamer

Electrochemical impedance spectroscopy

Endocrine disrupting compounds

Gold nanoparticles

Immune system

Interferon gamma

Limit of detection

Pleural fluid

Poly(3,4-propylenedioxythiophene)

Tuberculosis

Additional Fields

Identifer	oai:union.ndltd.org:netd.ac.za/oai:union.ndltd.org:uwc/oai:etd.uwc.ac.za:11394/5507
Date	January 2017
Creators	Sidwaba, Unathi
Contributors	Iwuoha, Emmanuel I.
Publisher	University of the Western Cape
Source Sets	South African National ETD Portal
Language	English
Detected Language	English
Rights	University of the Western Cape