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Previous issue date: 2017-02-23 / Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior (CAPES) / A rela??o entre a doen?a periodontal (DP) e a diabetes mellitus (DM) ? bidirecional, por?m, existe a necessidade de maiores evid?ncias em rela??o ao tratamento periodontal b?sico sobre os aspectos cl?nicos e a presen?a de bact?rias em pacientes com e sem diabetes. Dessa forma, portanto, o presente estudo teve por objetivo avaliar a influ?ncia da diabetes mellitus tipo II na efic?cia do tratamento periodontal b?sico atrav?s dos par?metros cl?nicos e microbiol?gicos da saliva. Foram tratados 51 pacientes entre 30 e 65 anos atrav?s da t?cnica ?Full Mouth Disinfection? (FMD), sendo 17 do grupo diab?tico (GD) e grupo n?o diab?tico (GND). Esses pacientes foram avaliados antes do in?cio do tratamento periodontal, aos 6 e 12 meses ap?s a sua conclus?o. No exame periodontal foram avaliados o ?ndice de Sangramento a Sondagem (ISS), ?ndice de Placa Vis?vel (IPV), Profundidade de Sondagem (PS), Recess?o Gengival (RG) e N?vel Cl?nico de Inser??o (NCI). Os par?metros sangu?neos avaliados foram glicose em jejum e hemoglobina glicada (HbA1C) apenas para o GD. As amostras de saliva foram coletadas antes da realiza??o de cada exame periodontal. Foi realizada a quantifica??o das esp?cies bacterianas Treponema denticola, Porphyromonas gingivalis, e Tannerella forsythia atrav?s da t?cnica Rea??o em cadeia da pol?meras em tempo real (PCR real-time). Os resultados mostraram quanto aos par?metros cl?nicos que houve uma melhora significativa para ISS, IPV e PS para ambos os grupos, enquanto que para o NCI apenas para o GD (p=0,023). Em rela??o aos par?metros microbiol?gicos, n?o houve diferen?as entre o grupo com diabetes e sem diabetes nos per?odos avaliados, apenas a esp?cie Tanerella forsythia apresentou diferen?a estat?stica significativa no per?odo de 12 meses (p=0,004), com maior mediana para o grupo GND. Na an?lise intragrupo, apenas o GD apresentou diferen?a estat?stica para todas as esp?cies avaliadas (p<0,05), na qual houve redu??o ap?s o tratamento, mas aumento ap?s a avalia??o de 6 meses. A esp?cie Porphyromonas gingivalis aumentou significativamente ap?s 12 meses, nesse per?odo de avalia??o obteve mediana maior que o baseline. A diabetes n?o influenciou na resposta do tratamento periodontal, ambos os grupos apresentaram melhora dos par?metros cl?nicos avaliados. / The relationship between periodontal disease (PD) and diabetes mellitus (DM) is bidirectional, however, there is a need for more evidence regarding basic periodontal treatment on clinical aspects and the presence of bacteria in patients with and without diabetes. Thus, the present study aimed to evaluate the influence of type II diabetes mellitus (DM) on the efficacy of basic periodontal treatment through the clinical and microbiological parameters of saliva. Fifty-one patients were treated between 30 and 65 years of age using the "Full Mouth Disinfection" (FMD) technique, 17 in the diabetic group (DG) and non-diabetic group (NDG). These patients were evaluated before the beginning of the periodontal treatment, at 6 and 12 months after its conclusion. In the periodontal examination, the Bleeding on Probing (BOP), Visible Plaque Index (VPI), Probing Depth (PD), Gingival Recession (RG) and Clinical Attachment Level (CAL) were evaluated. The blood parameters evaluated were fasting glucose and glycated hemoglobin (HbA1C) only for DG. Saliva samples were collected before each periodontal examination. Quantification of the bacterial species Treponema denticola, Porphyromonas gingivalis, and Tannerella forsythia through the real-time polymer chain reaction (PCR) technique was performed. The results showed that the clinical parameters showed a significant improvement for ISS, IPV and PS for both groups, whereas for NCI only for GD (p = 0.023). Regarding the microbiological parameters, there were no differences between the group with diabetes and no diabetes in the evaluated periods, only Tanerella forsythia presented a statistically significant difference in the 12-month period (p = 0.004), with a higher median for the NDD group. In the intragroup analysis, only the DG presented statistical difference for all species evaluated (p <0.05), in which there was reduction after treatment, but increase after the evaluation of 6 months. The species Porphyromonas gingivalis increased significantly after 12 months, in this period of evaluation it obtained median higher than baseline.
| Identifer | oai:union.ndltd.org:IBICT/oai:repositorio.ufrn.br:123456789/22639 |
| Date | 23 February 2017 |
| Creators | Almeida, Mariana Linhares |
| Contributors | 02569549410, http://lattes.cnpq.br/4649601602612601, Martins, Ana Rafaela Luz de Aquino, 05143199417, Shaddox, Luciana Machion, 28202312841, Gurgel, Bruno C?sar de Vasconcelos |
| Publisher | PROGRAMA DE P?S-GRADUA??O EM SA?DE COLETIVA, UFRN, Brasil |
| Source Sets | IBICT Brazilian ETDs |
| Language | Portuguese |
| Detected Language | English |
| Type | info:eu-repo/semantics/publishedVersion, info:eu-repo/semantics/masterThesis |
| Source | reponame:Repositório Institucional da UFRN, instname:Universidade Federal do Rio Grande do Norte, instacron:UFRN |
| Rights | info:eu-repo/semantics/openAccess |
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