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Previous issue date: 2012-02-27 / This descriptive study aimed to investigate the relationship between expression of immunological (TCD4 +) and virological (viral load) parameters, lipodystrophy syndrome and lifestyle variables of people living with HIV who underwent a program of physicalexercise. Initially, the sample was composed by 17 persons, recorded at the Department of Giselda Trigueiro Hospital Care (GTH), Natal-RN . With the passing of the stages of intervention (physical training program- PTP) the number of participants has changed (17, 9, 8 and 7) as the training phases (I, II, III and IV). Data collected were on total cholesterol, High Density Lipoprotein (HDL) and triglycerides. The % fat (% F), body mass index (BMI), waist-hip ratio (WHR), lean mass (LM), central fat (BF), total (TF) and peripheral (PF), weight and height were used to measure the morphological parameters. For control of variables (TCD4 +, viral load, Triglycerides, Cholesterol, HDL), the information contained in the blood tests every four months were investigated. After Phase I and II, it was used a structured interview. Then sampling was carried out considering the pre-and post-tests 1, 2, 3 and 4 (after 16, 32, 48 and 64 weeks of training, respectively). Daily, the intensity of the work was checked by the scale of perceived exertion for exercises adapted to resistance34. Procedures used were descriptive statistics (dispersion, absolute and relative frequencies, means, standard deviations and minimum and maximum values) as well as Spearman linear correlation adopting a significance level of p ≤ 0.05. Positive changes were observed for TCD4 + and viral load in all phases of the PTP. For the morphological components, the loss of central subcutaneous fat (CSF) and total subcutaneous fat (TSF) for both sexes and the decrease in % BF among women were the most dramatic results after the training phase I. For men, results were more significant to % F and LM in Phases I and II and peripheral subcutaneous fat (PSF) declined in all phases of the exercise. As for women, results were more expressive for % F and TM in the phases I and II and the PSF decreased in all phases of the exercise. Whereas for women, the waist/hip ratio (WCQ) and 0% F decreased and showed a positive association with triglycerides (WHR r * 0.82, p 0.042, r 0.88 TSF *, p 0.019 and r 1.00 ** CSF, p <0.001) and among men with limb subcutaneous fat (LSF)* r 0.65, p 0.029). The PTP provided improvement in the health, self-esteem and quality of life, proving to be a possible strategy to positively influence the expression of immunological parameters (TCD4 +) and virological (viral load) and morphological components of people living with HIV causing no deleterious effects in these parameters / Este estudo descritivo objetivou verificar a rela??o entre express?o dos par?metros imunol?gicos (TCD4+), virol?gicos (carga viral), s?ndrome lipodistr?fica e vari?veis do estilo de vida de pessoas que vivem com HIV Aids submetidos a um programa de exerc?cio resistido. A amostra, foi composta inicialmente por 17 pessoas, registrados no N?cleo de Atendimento do Hospital Giselda Trigueiro (HGT)/Natal-RN. Com o transcorrer das fases da interven??o (Programa de Exerc?cios Resistidos/PER) o n?mero de participantes se modificou (17, 9, 8 e 7) conforme as fases de treinamento (I, II, III e IV). Foram coletados dados do Colesterol total, HDL e triglicer?deos. O % de gordura (%G), ?ndice de massa corporal (IMC), raz?o cintura-quadril (RCQ), massa magra (MM), gordura central (GC), total (GT) e perif?rica (GP), peso e altura foram utilizados para mensurar os par?metros morfol?gicos. Para controle das vari?veis (TCD4+, CARGA VIRAL, Triglicer?deos, Colesterol, HDL) foram investigadas as informa??es contidas nos exames realizados a cada quatro meses. Foi utilizada a entrevista estruturada ap?s FASE I e II. As coletas foram realizadas considerando o pr? e p?s-testes 1, 2, 3 e 4 (ap?s 16, 32, 48 e 64 semanas de treinamento, respectivamente). A intensidade do trabalho foi verificada diariamente atrav?s da Escala de percep??o de esfor?o adaptada para exerc?cios de resist?ncia34. Foram utilizados procedimentos da estat?stica descritiva (dispers?o, frequ?ncias relativas e absolutas, m?dias, desvios padr?o e valores m?nimos e m?ximos) e a correla??o linear de Spearman adotando-se um nivel de significancia de p≤0,05. Foram observadas mudan?as positivas para TCD4+ e carga viral em todas as fases do PER. Para os componentes morfol?gicos, a perda de gordura subcut?nea central (GSC) e gordura subcut?nea total (GST) para ambos os sexos e a diminui??o do %G entre as mulheres foram os resultados mais expressivos ap?s o treinamento Fase I. Para homens os resultados foram mais expressivos para % G e MM nas Fases I e II e a GSP diminuiu em todas as fases do exerc?cio. J? para mulheres diminuiu a RCQ e %G e apresentou rela??o positiva com o triglicer?deos (RCQ r 0,82*, p 0,042 , GST r 0,88*, p 0,019 e GSC r 1,00**, p <0,001) e entre os homens com gordura subcut?nea dos membros (GSM) r 0,65*, p 0,029). O PER proporcionou melhora no quadro de sa?de, autoestima e qualidade de vida, demonstrando ser uma estrat?gia poss?vel de influenciar positivamente na express?o dos par?metros imunol?gicos (TCD4+), virol?gicos (carga viral) e de componentes morfol?gicos de pessoas vivendo com HIV Aids n?o causando efeitos delet?rios nos referidos par?metros
| Identifer | oai:union.ndltd.org:IBICT/oai:repositorio.ufrn.br:123456789/13253 |
| Date | 27 February 2012 |
| Creators | Soares, Themis Cristina Mesquita |
| Contributors | CPF:23334118053, http://lattes.cnpq.br/8414353396087915, Okano, Alexandre Hideki, CPF:69806217934, http://lattes.cnpq.br/9586370984131426, Morais, Fatima Raquel Rosado, CPF:79260748453, http://lattes.cnpq.br/8086396650395631, Ara?jo, Ivonete Batista de, CPF:05614082468, http://lattes.cnpq.br/3872552451523411, Santos, Ronaldo Vagner Thomatieli dos, CPF:17304186860, http://lattes.cnpq.br/9928572887023286, Knackfuss, Maria Irany |
| Publisher | Universidade Federal do Rio Grande do Norte, Programa de P?s-Gradua??o em Ci?ncias da Sa?de, UFRN, BR, Ci?ncias da Sa?de |
| Source Sets | IBICT Brazilian ETDs |
| Language | Portuguese |
| Detected Language | English |
| Type | info:eu-repo/semantics/publishedVersion, info:eu-repo/semantics/doctoralThesis |
| Format | application/pdf |
| Source | reponame:Repositório Institucional da UFRN, instname:Universidade Federal do Rio Grande do Norte, instacron:UFRN |
| Rights | info:eu-repo/semantics/openAccess |
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