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Previous issue date: 2012-02-16 / Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior / Oral Lichen Planus (OLP) is a relatively common, cronic inflammatory disease. Its etiopathogenesis is no completely understood and several factors have proposed in attempt to
explain the appearance, variety of clinical manifestations and periods of exacerbation and remission of the symptons of the lesions. The objective of the present study was to assess the
presence of local factors, systemic diseases and levels of anxiety in patients with OLP, investigating their association with the clinical characteristics of the lesions. The sample
consisted of 37 patients with histopathologically confirmed OLP that were submitted to a clinical exam to evaluate the presence of smoking habits, consumption of alcoholic beverages,
diabetes mellitus, hypertension and hepatitis C virus (HCV) infection. The existence of skin lesions, as well as the time course, clinical form, symptomatology, number and location of the
oral lesions were also registered. The trait anxiety was measured by Spielberger s Stai-Trait Anxiety Inventory (STAI), and to associate the variables we used the chi-square or Fisher s
exact test. It was observed that females were the most affected (75%) and the mean age of the
patients was 53,3 years. Most cases were non-smoker (97,3%) and none was drinker. Diabetes mellitus and hypertension were present in 10,8% e 16,2% of the sample, respectively and only
one patient was HCV-seropositive (2,7%). Moderate levels of anxiety were seen in most cases (78,4%) and 21,6% had elevated levels. The oral lesions persisted in 95% of the cases for a period of 6 months to 13 years. The erosive form was the most prevalent (57,1%) and symptons were reported by 45,7% of the patients. Multiple lesions were frequent (60%),
affecting mainly the buccal mucosa, followed by gums e tongue. There was no significant association of the presence of diabetes mellitus, hypertension and levels of anxiety with the
clinical form or symptomatology of the oral lesions (p>0,005), despite a trend in patients with hypertension to have erosive lesions. It was concluded that, in the sample studied, moderate
levels of anxiety were commonly observed, and the HCV infection apparently is not related to the onset of the OLP. In this study, the presence of diabetes mellitus, hypertension and levels
of anxiety seem not to be associated with the clinical characteristics of the lesions of OLP / O L?quen Plano Oral (LPO) ? uma doen?a inflamat?ria cr?nica relativamente comum. Sua etiopatogenia n?o est? completamente esclarecida e diversos fatores foram propostos na
tentativa de explicar o surgimento, variedade de aspectos cl?nicos e os per?odos de remiss?o e exacerba??o dos sintomas das les?es. O objetivo deste trabalho foi estudar a presen?a de
fatores locais, altera??es sist?micas e n?veis de ansiedade em pacientes com LPO, investigando sua associa??o com as caracter?sticas cl?nicas das les?es. A amostra foi constitu?da por 37 pacientes com LPO confirmado histopatologicamente, os quais foram submetidos a exame cl?nico para avaliar a presen?a do tabagismo, consumo de bebidas alco?licas, diabetes mellitus, hipertens?o arterial e infec??o pelo v?rus da hepatite C (HCV). A
exist?ncia de les?es cut?neas, bem como o tempo de evolu??o, padr?o cl?nico, sintomatologia, quantidade e localiza??o das les?es orais tamb?m foram registradas. O tra?o ansioso foi
mensurado atrav?s do Invent?rio de Ansiedade Tra?o-Estado (IDATE) de Spielberger, e para associar as vari?veis, foram utilizados o teste qui-quadrado de Pearson ou o teste exato de
Fisher. Observou-se que o g?nero feminino foi o mais afetado (75%) e a m?dia de idade dos pacientes foi 53,3 anos. A maioria dos casos eram n?o-fumantes (97,3%) e nenhum era
etilista. A diabetes mellitus e a hipertens?o arterial estiveram presentes em 10,8% e 16,2% da amostra, respectivamente e apenas um paciente era HCV-soropositivo (2,7%). N?veis
moderados de ansiedade foram vistos na maioria dos casos (78,4%) e 21,6% tinham n?veis elevados. As les?es orais persistiram em 95% da amostra por per?odo de 6 meses a 13 anos. A forma erosiva foi a mais prevalente (57,1%) e os sintomas foram relatados por 45,7% dos casos. Les?es m?ltiplas foram freq?entes (60%), surgindo principalmente na mucosa jugal, seguida da gengiva e l?ngua. N?o houve associa??o estatisticamente significativa da presen?a de diabetes mellitus, hipertens?o arterial e os n?veis de ansiedade com a forma cl?nica e a sintomatologia das les?es (p>0.005), apesar da tend?ncia dos pacientes hipertensos a apresentar les?es erosivas. Concluiu-se que, na amostra estudada, n?veis moderados de
ansiedade foram frequentemente observados, e a infec??o pelo HCV aparentemente n?o est? relacionada ao surgimento do LPO. Neste estudo, a presen?a da diabetes mellitus, hipertens?o
arterial e os n?veis de ansiedade parecem n?o estar associados ?s caracter?sticas cl?nicas das les?es de LPO
| Identifer | oai:union.ndltd.org:IBICT/oai:repositorio.ufrn.br:123456789/17120 |
| Date | 16 February 2012 |
| Creators | Barbosa, Nat?lia Guimar?es |
| Contributors | CPF:14068850453, http://lattes.cnpq.br/8375651517819318, Soares, Maria Sueli Marques, CPF:39361527487, http://lattes.cnpq.br/8594514894937279, Silveira, Ericka Janine Dantas da, CPF:02869049420, http://lattes.cnpq.br/2186658404241838, Medeiros, Ana Miryam Costa de |
| Publisher | Universidade Federal do Rio Grande do Norte, Programa de P?s-Gradua??o em Patologia Oral, UFRN, BR, Odontologia |
| Source Sets | IBICT Brazilian ETDs |
| Language | Portuguese |
| Detected Language | English |
| Type | info:eu-repo/semantics/publishedVersion, info:eu-repo/semantics/masterThesis |
| Format | application/pdf |
| Source | reponame:Repositório Institucional da UFRN, instname:Universidade Federal do Rio Grande do Norte, instacron:UFRN |
| Rights | info:eu-repo/semantics/openAccess |
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