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Previous issue date: 2010-10-17 / OBJECTIVE: Evaluating the kit-Bh performance in carrying out of breast
biopsies. METHODS: They were randomly selected a sample of 30 patients with breast
cancer undergoing mastectomy, based on the results of a pilot study from February 2008
to April 2010. They were excluded women with had not palpable, stone-hard
consistency tumors, previous surgical manipulation or that contains liquid. Using the
helicoid biopsy Kit (kit Bh) and an equipment Core biopsy with cannula and needle and
14 gauge respectively, it was collected a fragment of sound equipment in the area and in
tumors in each specimen, totaling 120 fragments for histological study. For data analysis,
it was defined a 95% confidence level and used the SPSS-13 version, the Kappa index
and the parametric Student t test. RESULTS: Mean age of patients was 51.6 years (? 11.1
years). The infiltrating ductal carcinoma showed a higher incidence, 26 cases
(86.7%). The Core biopsy had a sensitivity of 93.3%, specificity of 100% and accuracy
96.7%, while the helicoid biopsy had a sensitivity of 96.7%, specificity of 100% and
accuracy 98.3%. By comparing the histology of tumors and the fragments of biopsies,
there was high degree of agreement in diagnoses (kappa of 0.93 with p <0.05)
CONCLUSION: Both devices provided the histological diagnosis of lesions with high
accuracy. Results of this study showed that the helicoid biopsy is a reliable alternative in
22
the preoperative diagnosis of breast lesions. Further studies in vivo better will define the
role of Kit Bh in the diagnosis of these lesions / OBJETIVO: avaliar o desempenho do Kit Bh na realiza??o de biopsias
mam?rias. M?TODOS: de fevereiro de 2008 a abril de 2010, com base nos
resultados de um estudo piloto, selecionou-se aleatoriamente uma amostra
composta de 30 pacientes portadoras de c?ncer de mama submetidas a
mastectomia. Exclu?ram-se as mulheres portadoras de tumor que tivesse
consist?ncia p?trea, n?o palp?vel, com manipula??o cir?rgica pr?via ou que
contivesse l?quido. Utilizando-se o Kit de biopsia helic?ide ( Kit Bh ) e um
equipamentos de Core biopsy com c?nula e agulha de 14 gauge
respectivamente, coletou-se um fragmento por equipamento em ?rea s? e nos
tumores, em cada pe?a cir?rgica, totalizando 120 fragmentos para estudo
histol?gico. Para a an?lise dos dados definiu-se um n?vel de confian?a de 95%
e utilizou-se o software SPSS-vers?o 13, o ?ndice de concord?ncia Kappa e o
teste param?trico t de Student. RESULTADOS: a m?dia das idades das
pacientes foi de 51,6 anos (? 11,1 anos). O Carcinoma ductal infiltrante
apresentou maior incid?ncia, 26 casos (86,7%). A Core biopsy apresentou
sensibilidade de 93,3%, especificidade de 100% e acur?cia de 96,7%,
enquanto a Biopsia helic?ide teve sensibilidade de 96,7%, especificidade de
100% e acur?cia de 98,3%. Na compara??o entre a histologia dos tumores e
dos fragmentos de biopsias houve alto grau de concord?ncia nos diagn?sticos (
Kappa igual a 0,93 com p<0,05) CONCLUS?ES: ambos os equipamentos
proporcionaram o diagn?stico histol?gico das les?es com alta acur?cia.Os
resultados deste estudo demonstraram que a biopsia helic?ide ? uma
alternativa confi?vel no diagnostico pr?-operat?rio de les?es mam?rias. Estudos mais aprofundados in vivo, definir?o melhor o papel do Kit Bh no
diagn?stico dessas les?es
| Identifer | oai:union.ndltd.org:IBICT/oai:repositorio.ufrn.br:123456789/13326 |
| Date | 17 October 2010 |
| Creators | Souza, Eliel de |
| Contributors | CPF:13049127449, http://lattes.cnpq.br/7869140767244263, Pinheiro, Luiz Gonzaga Porto, CPF:00345091353, http://lattes.cnpq.br/4121910252334757, Oliveira, Ana Katherine da Silveira Gon?alves de, CPF:42252725400, http://lattes.cnpq.br/3436756337251449, Maranh?o, T?cia Maria de Oliveira |
| Publisher | Universidade Federal do Rio Grande do Norte, Programa de P?s-Gradua??o em Ci?ncias da Sa?de, UFRN, BR, Ci?ncias da Sa?de |
| Source Sets | IBICT Brazilian ETDs |
| Language | Portuguese |
| Detected Language | English |
| Type | info:eu-repo/semantics/publishedVersion, info:eu-repo/semantics/masterThesis |
| Format | application/pdf |
| Source | reponame:Repositório Institucional da UFRN, instname:Universidade Federal do Rio Grande do Norte, instacron:UFRN |
| Rights | info:eu-repo/semantics/embargoedAccess |
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