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Wet Organic Field Effect Transistor as DNA sensor

<p>Label-free detection of DNA has been successfully demonstrated on field effect transistor (FET) based devices. Since conducting organic materials was discovered and have attracted more and more research efforts by their profound advantages, this work will focus on utilizing an organic field effect transistor (OFET) as DNA sensor.</p><p>An OFET constructed with a transporting fluidic channel, WetOFET, forms a fluid-polymer (active layer) interface where the probe DNA can be introduced. DNA hybridization and non-hybridization after injecting target DNA and non-target DNA were monitored by transistor characteristics. The Hysteresis area of transfer curve increased after DNA hybridization which may be caused by the increasing electrostatic screening induced by the increasing negative charge from target DNA. The different morphology of coating surface could also influence the OFET response.</p>

Identiferoai:union.ndltd.org:UPSALLA/oai:DiVA.org:liu-11761
Date January 2008
CreatorsChiu, Yu-Jui
PublisherLinköping University, The Department of Physics, Chemistry and Biology, Institutionen för fysik, kemi och biologi
Source SetsDiVA Archive at Upsalla University
LanguageEnglish
Detected LanguageEnglish
TypeStudent thesis, text

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