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000785132.pdf: 846444 bytes, checksum: e62ceaf45dd300613619d2fc1b769d3d (MD5) / Objetivo: Avaliar o crescimento neonatal dos descendentes de ratas espontaneamente hipertensas (SHR) submetidas a exercício em esteira motorizada. Metodologia: Ratas SHR e Wystar Kyoto (WKY) foram distribuídas em: sedentárias (SHR e WKY), exercitadas durante a prenhez (SHR EXP e WKY EXP) e exercitadas previamente – antes e durante a prenhez (SHR EXPP e WKY EXPP). Durante a prenhez, pesos corpóreos, glicemia e nível de lactato e triglicérides e pressão arterial foram determinados. No 10º dia de vida pós-natal, peso, glicemia e comprimento corporal e cranial dos filhotes e triglicéride hepático foram analisados. Resultados: Não houve diferença no peso e lactato durante a prenhez e no número de filhotes entre os grupos. O grupo WKE EXPP apresentou maior pressão arterial comparado aos grupos WKY EXP E WKY. SHR EXPP e WKY EXPP apresentaram maior nível de triglicéride que os grupos exercitados na prenhez e sedentários. SHR EXPP apresentou menor glicemia que os SHR EXP e SHR. Não houve diferença nos parâmetros dos filhotes, mas o comprimento corpóreo foi maior nos grupos WKY EXPP e SHR EXPP. Conclusão: O exercício prévio foi exaustivo para a linhagem WKY. O exercício durante a prenhez não foi prejudicial para as ratas SHR e beneficiou o comprimento corpóreo dos filhotes / Purpose: To evaluate the neonatal growth of the offspring of spontaneously hypertensive rats (SHR) subjected to treadmill exercise. Methods: SHR and Wystar Kyoto (WKY) rats were distributed into: sedentary group (SHR and WKY), exercised during pregnancy (SHR EXP and WKY EXP) and exercised previously and during pregnancy (SHR EXPP and WKY EXPP). During pregnancy, body weight, blood glucose, lactate and triglycerides levels and blood pressure were determined. At 10th day of life, body weight, blood glucose, and body and cranial length and hepatic triglycerides were analyzed. Results: There was no difference in body weight and lactate level during pregnancy, and number of pups among groups. The WKY EXPP group presented higher blood pressure than WKY and WKY EXP groups. SHR EXPP and WKY EXPP showed higher triglyceride level compared to groups trained in pregnancy and sedentary. SHR EXPP showed lower blood glucose than SHR and SHR EXP. There was no difference in the parameters of the newborns. In addition, body length was higher in WKY EXPP and SHR EXPP groups. Conclusion: The previous exercise was exhausting for the WKY strain. Exercise during pregnancy is not harmful to SHR rats and benefited the body length of offspring
| Identifer | oai:union.ndltd.org:IBICT/oai:repositorio.unesp.br:11449/110584 |
| Date | 17 February 2014 |
| Creators | Corrêa, Mikaela da Silva [UNESP] |
| Contributors | Universidade Estadual Paulista (UNESP), Peraçoli, José Carlos [UNESP], Damasceno, Débora Cristina [UNESP] |
| Publisher | Universidade Estadual Paulista (UNESP) |
| Source Sets | IBICT Brazilian ETDs |
| Language | Portuguese |
| Detected Language | Portuguese |
| Type | info:eu-repo/semantics/publishedVersion, info:eu-repo/semantics/masterThesis |
| Format | 46 f. |
| Source | Aleph, reponame:Repositório Institucional da UNESP, instname:Universidade Estadual Paulista, instacron:UNESP |
| Rights | info:eu-repo/semantics/openAccess |
| Relation | -1, -1, -1 |
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