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Verifica??o da atividade antif?ngica dos extratos vegetais sobre esp?cies de fungos do g?nero Aspergillus. / Verification of the antifungal activity of the vegetable extracts species of the gender Aspergillus.

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Previous issue date: 2008-04-16 / Many areas are involved in the search for new substances from plants. The new global
trends of a concern for biodiversity and the ideas of sustainable development have brought
new air to studies of Brazilian medicinal plants. New lines of research were established in
Brazilian universities, some of them seeking solid basis for the validation of the use of
medicinal plants, thus justifying this work, using aqueous extracts of plants place of
occurrence, such as Cinnamomum spp., Mentha piperita and Passiflora foetida, inhibition of
growth of some species of the genus Aspergillus tox?genas, previously studied in the literature
and identified as antifungal and encouraging the use of plants to replace chemicals. Using the
method of minimum inhibitory concentration in agar, with the technique of dilution plate (Pour-Plate), being held dilutions of different extracts, from a solution of 5% and resulting in
the dilution of 2.5% and 1.25%. Batteries tests were incubated at the 36oC. It was held also
test for sensitivity to antifungal commercial - Ketoconazole. It was observed that the aqueous
extract of Cinnamomum spp. was able to inhibit the mycelial growth of A. flavus and A.
carbonarius at concentrations of 2.5% and 5% in readings of 48 hours. The other aqueous
extracts, used in this work, showed no inhibitory effect of mycelial growth of fungi tested. / Muitas ?reas est?o envolvidas na pesquisa de novas subst?ncias oriundas de
plantas. As novas tend?ncias globais de uma preocupa??o com a biodiversidade e as id?ias de
desenvolvimento sustent?vel trouxeram novos ares aos estudos das plantas medicinais
brasileiras. Novas linhas de pesquisa foram estabelecidas em universidades brasileiras,
algumas delas buscando bases s?lidas para a valida??o do uso de plantas medicinais,
justificando, assim, a realiza??o deste trabalho, utilizando extratos aquosos de plantas de
ocorr?ncia local, como a Cinnamomum spp., Mentha piperita e Passiflora foetida, na inibi??o
do crescimento de algumas esp?cies tox?genas do g?nero Aspergillus, previamente
pesquisadas na literatura e apontadas como antif?ngicas e favorecendo a utiliza??o de plantas
em substitui??o de produtos qu?micos. Utilizando o m?todo da concentra??o m?nima
inibit?ria em agar, com a t?cnica de dilui??o em placa (Pour-Plate), sendo realizadas dilui??es
dos diferentes extratos, partindo de uma solu??o de 5% e obtendo-se as dilui??es de 2,5% e
1,25%. As baterias testes foram incubadas a 36o C. Foi realizado, tamb?m, teste de
sensibilidade ao antif?ngico comercial Cetoconazol. Observou-se que o extrato aquoso de
Cinnamomum spp. mostrou-se capaz de inibir o crescimento micelial de A. flavus e A.
carbonarius nas concentra??es de 2,5% e 5%, nas leituras de 48 horas. Os demais extratos
aquosos, utilizados neste trabalho, n?o apresentaram efeito inibit?rio do crescimento micelial
dos fungos testados.

Identiferoai:union.ndltd.org:IBICT/oai:localhost:tede/869
Date16 April 2008
CreatorsVila Nova, Ana Cla?dia da Silva
ContributorsBorba, Helcio Resende
PublisherUniversidade Federal Rural do Rio de Janeiro, Programa de P?s-Gradua??o em Microbiologia Veterin?ria, UFRRJ, Brasil, Microbiologia Veterin?ria
Source SetsIBICT Brazilian ETDs
LanguagePortuguese
Detected LanguageEnglish
Typeinfo:eu-repo/semantics/publishedVersion, info:eu-repo/semantics/masterThesis
Formatapplication/pdf
Sourcereponame:Biblioteca Digital de Teses e Dissertações da UFRRJ, instname:Universidade Federal Rural do Rio de Janeiro, instacron:UFRRJ
Rightsinfo:eu-repo/semantics/openAccess

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