Artificial intelligence (AI) has been seeing a great amount of hype around it for a few years but more so now in the field of diagnostic medical imaging. AI-based diagnoses have shown improvements in detecting the smallest abnormalities present in tumors and lesions. This can tremendously help public healthcare. There is a large amount of data present in the field of biomedical imaging with the hospitals but only a small amount is available for the use of research due to data and privacy protection. The task of manually segmenting tumors in this magnetic resonance imaging (MRI) can be quite expensive and time taking. This segmentation and classification would need high precision which is usually performed by medical experts that follow clinical medical standards. Due to this small amount of data when used with machine learning models, the trained models tend to overfit. With advancing deep learning techniques it is possible to generate images using Generative Adversarial Networks (GANs). GANs has garnered a heap of attention towards itself for its power to produce realistic-looking images, videos, and audios. This thesis aims to use the synthetic images generated by progressive growing GANs (PGGAN) along with real images to perform segmentation on brain tumor MRI. The idea is to investigate whether the addition of this synthetic data improves the segmentation significantly or not. To analyze the quality of the images produced by the PGGAN, Multi-scale Similarity Index Measure (MS-SSIM) and Sliced Wasserstein Distance (SWD) are recorded. To exam-ine the segmentation performance, Dice Similarity Coefficient (DSC) and accuracy scores are observed. To inspect if the improved performance by synthetic images is significant or not, a parametric paired t-test and non-parametric permutation test are used. It could be seen that the addition of synthetic images with real images is significant for most cases in comparison to using only real images. However, this addition of synthetic images makes the model uncertain. The models’ robustness is tested using training-free uncertainty estimation of neural networks.
| Identifer | oai:union.ndltd.org:UPSALLA1/oai:DiVA.org:liu-182048 |
| Date | January 2021 |
| Creators | Nijhawan, Aashana |
| Publisher | Linköpings universitet, Statistik och maskininlärning |
| Source Sets | DiVA Archive at Upsalla University |
| Language | English |
| Detected Language | English |
| Type | Student thesis, info:eu-repo/semantics/bachelorThesis, text |
| Format | application/pdf |
| Rights | info:eu-repo/semantics/openAccess |
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