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Estudo randomizado comparando an?lise de bioimped?ncia el?trica e avalia??o cl?nica para determinar peso seco em hemodi?lise

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Previous issue date: 2015-03-02 / Background: Adequate control of extracellular volume is a major goal of hemodialysis (HD) in chronic kidney disease (CKD) patients. Fluid overload contributes significantly to the high morbidity and mortality rates of these patients. The body composition monitor by multifrequency bioimpedance (BCM) is equipment tool able to quantify objectively and accurately the hydration status of each patient. The aim of this study was to compare the efficacy between bioelectrical impedance analysis (BIA) and clinical evaluation to adjust dry weight (DW) in HD patients. Methods: A randomized crossover study. Patients were randomized in two groups: A, in which patients were evaluated by the clinical evaluation and B, wherein the dry weight of the patients was assessed by BIA, for four weeks. Following a wash-out period a crossover between the groups was performed and patients observed for 1 month. The study was approved by the ethics committee of Pontificia Cat?lica University of Rio Grande do Sul. Results: The study included 57 CKD in HD. Blood pressure, hydration parameters and DW were not significantly different between the groups indicating an equivalence between BIA and clinical evaluation treatments to determine DW in HD. Conclusion: The study shows that the BIA is similar than the clinical evaluation to guide ultrafiltration and determine DW in HD. / Introdu??o: O controle adequado do volume extracelular ? um dos principais objetivos da terapia renal substitutiva (TRS) em doentes renais cr?nicos (DRC), pois a sobrecarga h?drica contribui com as altas taxas de morbimortalidade destes pacientes. O monitor de composi??o corporal por bioimped?ncia multifrequencial (BCM) ? um equipamento capaz de quantificar de maneira objetiva o estado de hidrata??o de cada paciente, visando avaliar o peso seco (PS). O objetivo desse estudo foi comparar a efic?cia entre an?lise por bioimped?ncia el?trica (BIA) e avalia??o cl?nica (AC) para adequa??o de PS em pacientes em hemodi?lise (HD). M?todo: Estudo randomizado, do tipo crossover. Os pacientes foram randomizados em dois grupos: A, iniciou o estudo com o PS sendo determinado por AC e B, por BIA, por 1 m?s. Ap?s, foi realizado o cruzamento dos grupos e invers?o dos tratamentos, por mais 1 m?s. O estudo foi aprovado pelo comit? de ?tica da Pontif?cia Universidade Cat?lica do Rio Grande do Sul. Resultados: Participaram do estudo 57 DRC em HD. Comparando os dois tratamentos para dados de press?o arterial, par?metros de hidrata??o e PS, independente dos grupos, os resultados n?o detectaram diferen?as significativas, apontando uma equival?ncia entre os tratamentos de BIA e AC para determinar PS em HD. Conclus?o: Estudo demonstra que a BIA ? equivalente ? AC para guiar a ultrafiltra??o e determinar PS em HD.

Identiferoai:union.ndltd.org:IBICT/oai:tede2.pucrs.br:tede/6071
Date02 March 2015
CreatorsBreitsameter, Guilherme
ContributorsFigueiredo, Ana Elizabeth
PublisherPontif?cia Universidade Cat?lica do Rio Grande do Sul, Programa de P?s-Gradua??o em Medicina e Ci?ncias da Sa?de, PUCRS, Brasil, Faculdade de Medicina
Source SetsIBICT Brazilian ETDs
LanguagePortuguese
Detected LanguageEnglish
Typeinfo:eu-repo/semantics/publishedVersion, info:eu-repo/semantics/masterThesis
Formatapplication/pdf
Sourcereponame:Biblioteca Digital de Teses e Dissertações da PUC_RS, instname:Pontifícia Universidade Católica do Rio Grande do Sul, instacron:PUC_RS
Rightsinfo:eu-repo/semantics/openAccess
Relation7620745074616285884, 600, 600, 600, -8624664729441623247, -969369452308786627

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