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Spatial epidemiology of tuberculosis in Hong Kong.

Pang, Tak Ting Phoebe. / "September 2010." / Thesis (M.Phil.)--Chinese University of Hong Kong, 2010. / Includes bibliographical references (leaves 153-161). / Abstracts in English and Chinese. / Acknowledgement --- p.I / Abstract --- p.II / 摘要 --- p.IV / List of Figures --- p.V / List of Tables --- p.VII / Abbreviations --- p.VIII / Chapter CHAPTER ONE --- INTRODUCTION --- p.1 / Chapter 1.1 --- Historical perspective of tuberculosis --- p.1 / Chapter 1.1.1 --- Sanatorium care --- p.2 / Chapter 1.1.2 --- Vaccination --- p.2 / Chapter 1.1.3 --- Drug treatment --- p.3 / Chapter 1.1.4 --- Transmission dynamics of tuberculosis --- p.3 / Chapter 1.1.5 --- Resurgence of tuberculosis --- p.4 / Chapter 1.2 --- Current global and local tuberculosis epidemiology --- p.6 / Chapter 1.2.1 --- "Tuberculosis and HIV/AIDS, drug resistance in the world" --- p.6 / Chapter 1.2.2 --- Global epidemiology of tuberculosis --- p.9 / Chapter 1.2.3 --- Local epidemiology of tuberculosis --- p.9 / Chapter 1.2.4 --- "Tuberculosis, HIV/AIDS and drug resistance in Hong Kong" --- p.14 / Chapter 1.2.5 --- Approaches in studying tuberculosis epidemiology --- p.15 / Chapter 1.3 --- Determinants of tuberculosis epidemiology --- p.17 / Chapter 1.3.1 --- TB determinants in the triad of epidemiology --- p.17 / Chapter 1.3.2 --- Rise of spatial epidemiology --- p.18 / Chapter 1.4 --- Recent developments of spatial epidemiology --- p.21 / Chapter 1.4.1 --- Spatial epidemiology and infectious disease --- p.21 / Chapter 1.4.2 --- Disease mapping --- p.22 / Chapter 1.4.3 --- Geographic information system --- p.22 / Chapter 1.4.4 --- Statistics in spatial epidemiology --- p.23 / Chapter CHAPTER TWO --- LITERATURE REVIEW --- p.24 / Chapter 2.1 --- Objective of literature review --- p.24 / Chapter 2.2 --- Literature search --- p.25 / Chapter 2.2.1 --- Strategy for literature search --- p.25 / Chapter 2.2.2 --- Results for literature search --- p.25 / Chapter 2.3 --- Spatial perspective in tuberculosis epidemiology --- p.31 / Chapter 2.3.1 --- Mapping the spatial pattern --- p.32 / Chapter 2.3.2 --- Understanding the spatial pattern --- p.32 / Chapter 2.3.3 --- Modelling the spatial pattern --- p.33 / Chapter 2.4 --- Neighbourhood determinants of tuberculosis --- p.34 / Chapter 2.4.1 --- TB and demographics --- p.35 / Chapter 2.4.2 --- TB and socioeconomic status --- p.36 / Chapter 2.4.3 --- TB and the environment --- p.38 / Chapter 2.4.4 --- TB and care factors --- p.40 / Chapter 2.5 --- Techniques applied in studying tuberculosis epidemiology --- p.41 / Chapter 2.5.1 --- Constructing spatial data --- p.41 / Chapter 2.5.2 --- Disease maps used --- p.45 / Chapter 2.5.3 --- "Integrated approach using spatial statistics, conventional statistics and molecular analysis" --- p.52 / Chapter 2.6 --- Research gap and thesis objectives --- p.55 / Chapter 2.6.1 --- Research gap --- p.55 / Chapter 2.6.2 --- Thesis objective --- p.56 / Chapter CHAPTER THREE --- METHODOLOGY --- p.57 / Chapter 3.1 --- Rationale and approach --- p.57 / Chapter 3.1.1 --- Logical flow of the study --- p.57 / Chapter 3.1.2 --- Methodological flow of the study --- p.60 / Chapter 3.2 --- Choosing spatial units --- p.63 / Chapter 3.3 --- Data collection --- p.69 / Chapter 3.3.1 --- Tuberculosis data --- p.70 / Chapter 3.3.2 --- Spatial data --- p.70 / Chapter 3.3.3 --- Neighbourhood data --- p.70 / Chapter 3.4 --- Data manipulation --- p.73 / Chapter 3.4.1 --- Tuberculosis data --- p.73 / Chapter 3.4.2 --- Spatial data --- p.74 / Chapter 3.4.3 --- Neighbourhood data --- p.74 / Chapter 3.5 --- Centrographic analysis --- p.76 / Chapter 3.5.1 --- Types of centrographic statistics --- p.76 / Chapter 3.6 --- Exploratory spatial data analysis --- p.78 / Chapter 3.6.1 --- Spatial proximity matrix --- p.78 / Chapter 3.6.2 --- Moran's Index --- p.79 / Chapter 3.6.3 --- Local Indicator of Spatial Association --- p.79 / Chapter 3.7 --- Explanatory analysis --- p.81 / Chapter 3.7.1 --- Selecting variables for modelling --- p.82 / Chapter 3.7.2 --- Ordinary linear regression --- p.82 / Chapter 3.7.3 --- Geographically weighted regression --- p.83 / Chapter CHAPTER FOUR --- RESULTS --- p.85 / Chapter 4.1 --- Overview --- p.85 / Chapter 4.1.1 --- Individual level --- p.85 / Chapter 4.1.2 --- Aggregated level --- p.89 / Chapter 4.2 --- Results for centrographic analysis --- p.97 / Chapter 4.3 --- Results for exploratory spatial data analysis --- p.101 / Chapter 4.3.1 --- Results for Moran's Index --- p.101 / Chapter 4.3.2 --- Results for Local Indicator of Spatial Association --- p.103 / Chapter 4.4 --- Results for explanatory analysis --- p.110 / Chapter 4.4.1 --- Correlation analysis and variables selection --- p.110 / Chapter 4.4.2 --- Results for ordinary linear regression --- p.114 / Chapter 4.4.3 --- Results for geographically weighted regression --- p.116 / Chapter CHAPTER FIVE --- DISCUSSION --- p.131 / Chapter 5.1 --- Preamble --- p.131 / Chapter 5.1.1 --- Methods overview --- p.132 / Chapter 5.1.2 --- Results overview --- p.132 / Chapter 5.1.3 --- Layout of this chapter --- p.134 / Chapter 5.2 --- Neighbourhood determinants in relation to TB --- p.135 / Chapter 5.2.1 --- Crowding and tuberculosis --- p.135 / Chapter 5.2.2 --- Poverty and tuberculosis --- p.137 / Chapter 5.2.3 --- Immigrants and tuberculosis --- p.138 / Chapter 5.2.4 --- Marital status and tuberculosis --- p.139 / Chapter 5.2.5 --- Implication of local parameter estimates of association --- p.140 / Chapter 5.3 --- Study design for spatial epidemiology --- p.142 / Chapter 5.3.1 --- Application of spatial dependence in spatial epidemiology --- p.142 / Chapter 5.3.2 --- Choosing spatial units --- p.144 / Chapter 5.4 --- Methodological concern in this study --- p.146 / Chapter 5.4.1 --- Concern over disease mapping --- p.146 / Chapter 5.4.2 --- Application of geographically weighted regression --- p.148 / Chapter 5.5 --- Limitation of the study --- p.150 / Chapter 5.6 --- Conclusion --- p.152 / REFERENCE --- p.153 / APPENDIX --- p.162 / Appendix 1 How to calculate TB SNR? --- p.162 / Appendix 2 How GWR works? --- p.164 / Appendix 3 What is AIC? --- p.165 / Appendix 4 How Monte Carlo test works? --- p.166 / Appendix 5 List of GWR output --- p.167

Identiferoai:union.ndltd.org:cuhk.edu.hk/oai:cuhk-dr:cuhk_327115
Date January 2010
ContributorsPang, Tak Ting Phoebe., Chinese University of Hong Kong Graduate School. Division of Public Health.
Source SetsThe Chinese University of Hong Kong
LanguageEnglish, Chinese
Detected LanguageEnglish
TypeText, bibliography
Formatprint, xii, 167 leaves : ill. (chiefly col.), col. maps ; 30 cm.
CoverageChina, Hong Kong, Hong Kong
RightsUse of this resource is governed by the terms and conditions of the Creative Commons “Attribution-NonCommercial-NoDerivatives 4.0 International” License (http://creativecommons.org/licenses/by-nc-nd/4.0/)

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