Background: Patients with d-transposition of the great arteries after Senning or Mustard procedure are at increased risk for arrhythmias. Especially atrial arrhythmias represent a major threat in this patient population. Early detection of clinical and subclinical arrhythmias may prevent major cardiac events. Therefore, this study aimed to evaluate the ability of the Medtronic REVEAL LINQ to detect atrial arrhythmias in adult patients after atrial switch procedure and compare the effectiveness of detecting clinically relevant arrhythmias to conventional Holter monitoring.
METHODS: The database of the Heart Center Leipzig, Department for pediatric cardiology was analyzed for patients after atrial switch procedure and implantation of a Medtronic REVEAL LINQ (Medtronic Inc., Minneapolis, Minnesota). After informed consent was obtained, patients were followed up for 1 year including Holter ECG tracings and device interrogation every 3 months. In addition, symptoms were determined using a standardized questionnaire completed by the patient.
RESULTS: The analysis is based on 10 patients aged 34.5 years (range 27-46 years), of which 8 had a Senning - and 2 had a Mustard procedure. The comparison of the number of arrhythmia episodes detected by Holter and LINQ showed significantly more detected episodes using LINQ (p 0.014). Data showed that no therapy adjustments were recorded as a consequence of Holter ECG findings, whereas two changes in medication were documented due to arrhythmia detection via LINQ. When analyzing possible correlations between subjective symptoms reported in the standardized questionnaire and the number of episodes documented, there was a significant correlation of subjective symptoms and arrhythmia episodes in LINQ (p 0.014), whereas no correlation could be demonstrated between subjective symptoms and the number of episodes detected by Holter monitoring (p 0.394).
CONCLUSION: In patients after Senning or Mustard procedure, the Medtronic REVEAL LINQ seems to be superior in the identification of subclinical arrhythmia burden in comparison to standard Holter ECG.
| Identifer | oai:union.ndltd.org:DRESDEN/oai:qucosa:de:qucosa:75501 |
| Date | 22 July 2021 |
| Creators | Piegsa, Julia, Markel, Franziska, Dähnert, Ingo, Michaelis, Anna, Gebauer, Roman Antonin, Paech, Christian |
| Source Sets | Hochschulschriftenserver (HSSS) der SLUB Dresden |
| Language | English |
| Detected Language | English |
| Type | info:eu-repo/semantics/submittedVersion, doc-type:preprint, info:eu-repo/semantics/preprint, doc-type:Text |
| Rights | info:eu-repo/semantics/openAccess |
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