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Previous issue date: 2015-09-30 / O sistema de temporizac?a?o circadiana (STC) compreende um conjunto de estruturas neurais, que incluem vias aferentes, como projec?o?es retinianas, que permitem a sincronizac?a?o dos ritmos biolo?gicos aos ciclos ambientais; um marcapasso central que gera o sinal circadiano e vias eferentes, que conectam o marcapasso aos efetores comportamentais. Entre os componentes centrais do STC, destaca-se o nu?cleo supraquiasma?tico (NSQ), classicamente reconhecido como a estrutural neural que rege a ritmicidade biolo?gica, e o folheto intergeniculado (FIG) do complexo geniculado lateral do ta?lamo, modulador do marcapasso. Nesse estudo, ambos os centros circadianos foram avaliados quanto a sua citoarquitetura, padra?o de inervac?a?o retiniana e conteu?do neuroqui?mco por meio da te?cnica de Nissl, de trac?ador neural e te?cnicas imuno-histoqui?micas no morcego Artibeus planirostris, microquiro?ptero comum no territo?rio brasileiro. Com base nessas te?cnicas foi possi?vel observar que o NSQ, no ni?vel rostral, exibe um formato aproximadamante triangular e no ni?vel me?dio e caudal, assume uma forma arredondada, ale?m de apresentar inervac?a?o retiniana bilateral, com leve predomina?ncia contralateral. O NSQ do Artibeus planirostris e? dotado de ce?lulas imunorreativas a vasopressina (VP), polipepti?deo intestital vasoativo (VIP), calbindina (CB) e calretinina (CR); fibras/terminiais imunorreativos a neuropepti?deo Y (NPY) e serotonina (5-HT), ale?m de marcac?a?o para protei?na aci?dica fribilar glial (GFAP). O FIG recebe projec?a?o retiniana bilateral e nos ni?veis rostral e me?dio exibe a forma de um fino folheto interposto entre o GLD e o GLV e a ni?vel caudal expande-se medialmente contornando o GLV, ale?m de conter ce?lulas que expressam NPY, CB e CR; terminais imunorreativos a 5-HT e marcac?a?o para GFAP. Esse e? o primeiro estudo a examinar o STC dessa espe?cie de quiro?ptero. Os dados indicam que o NSQ e FIG no Artibeus planirostris apresenta afere?ncias retinianas e conteu?do neuroqui?mico similar a outras espe?cies de mami?feros. / The circadian timing system (CTS) comprises a set of neural structures that include input pathways, such retinal projections, which allow the synchronization of the biological rhythms to environmental cycles; a central circadian pacemaker, which generates the circadian signal and output pathways connecting the pacemaker to the behavioral effectors. Among the major components of the STC, highlight the suprachiasmatic nucleus (SCN), classically known as the neural structure that governs biological rhythmicity, and the intergeniculate leaflet (FIG) of the thalamic lateral geniculate complex, modulator pacemaker. In this study, both circadian centers were evaluated in respect to their cytoarchiteture, pattern of the retinal innervations and chemical content with a Nissl stain, neural tracer and imunohistochemical techniques in bat Artibeus planirostris, common microchiropteran in Brazil. Based on these techniques was observed in rostral sections, the SCN had an approximately triangular shape and in middle and caudal sections, this nucleus assumed an ellipsoidal contour. It receives bilateral retinal in nervations, with discrete contralateral predominance and contains vasopressin (VP), vasoactive intestinal polypeptide (VIP), calbindin (CB) e calretinin (CR) immunoreactive cell bodies; neuropeptide Y (NPY) and serotonin (5-HT) imunopositive fibers/ terminals, besides to glial fibrillary acidic protein (GFAP) labeling. The IGL contains NPY, CB and CR immunoreactive perikarya and receives a bilateral retinal projection. The rostral and middle IGL had a leaflet shape between the DLG and VLG. At a caudal level it had a descending portions which outlines de VLG medially. This is the first report examining the CTS of these species of chiropteran. The results indicate that retinal input and chemical content of the SCN and IGL in Artibeus planirostris are similar other mammalian species. In contrast, the SCN of these bat transcend the classical organizational schemes proposed in the scientific literature. Hodological and molecular studies are needed to stablish a specific division of this structure in these species of chiropteran.
| Identifer | oai:union.ndltd.org:IBICT/oai:repositorio.ufrn.br:123456789/20418 |
| Date | 30 September 2015 |
| Creators | Santana, Nelyane Nayara Martins de |
| Contributors | 02588073425, http://lattes.cnpq.br/5233940343676740, Ladd, Fernando Vagner Lobo, 86967622153, http://lattes.cnpq.br/0907170560632356, Lucena, Eudes Euler de Souza, 01360681469, http://lattes.cnpq.br/6969519171915250, Engelberth, Rovena Clara Galv?o Janu?rio, Nascimento J?nior, Expedito Silva do |
| Publisher | Universidade Federal do Rio Grande do Norte, PROGRAMA DE P?S-GRADUA??O EM PSICOBIOLOGIA, UFRN, Brasil |
| Source Sets | IBICT Brazilian ETDs |
| Language | Portuguese |
| Detected Language | English |
| Type | info:eu-repo/semantics/publishedVersion, info:eu-repo/semantics/masterThesis |
| Source | reponame:Repositório Institucional da UFRN, instname:Universidade Federal do Rio Grande do Norte, instacron:UFRN |
| Rights | info:eu-repo/semantics/openAccess |
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