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Performance of the FIB-4 index in esophageal varices screening in patients with the diagnosis of liver cirrhosis / Desempeñ o del índice FIB-4 en el despistaje de vá rices esofá gicas en pacientes con el diagnóstico de cirrosis hepá tica

INTRODUCTION: The diagnosis of esophageal varices in cirrhotic patients is made by the upper gastrointestinal endoscopy. Multiple non-invasive predictors have been studied for the diag-nosis of esophageal varices. The objective of this study is to testthe FIB4 index as screening of esophageal varices in patients with liver cirrhosis. MATERIALS AND METHODS: A cross-sectional analytic study was developed in four national hospital using hepatic cirrhosis patient's medi-cal files. We assessed the information using univariate and bivariate analysis, sensitivity, speci-ficity, predictive positive and negative value, the positive and negative likelihood ratio calcu-lation of the esophageal varices screening and its size. We built ROC curve for every analysis group. RESULTS: The study included 289 liver cirrhosis patients. Most of the patients were male (54.33%). 77.85% patients had esophageal varices. The distribution of varices was 19.03%, 35.99% and 22.84% for large, medium and small varices, respectively. In the FIB-4 index analysis for the presence of varices, it was found a sensitivity of 81.3%, specificity of 37.5% (AUC: 0.57). The calculation for variceal size showed a sensitivity of 81.8%, specificity of 23.9% (AUC: 0.50). In the analysis of FIB-4 index for prophylaxis groups was found a sensitivity of 81.8% and a specificity of 28.5% (AUC: 0.54). CONCLUSIONS: The FIB-4 index has no good performance in the screening for the presence of esophageal varices and its size in liver cirrhosis patients. / Revisión por pares

Identiferoai:union.ndltd.org:PERUUPC/oai:repositorioacademico.upc.edu.pe:10757/655701
Date01 January 2020
CreatorsCá Lamo-Guzmá N, Bernardo, De Vinatea-Serrano, Luis, Piscoya, Alejandro, Segura, Eddy R.
PublisherSociedad de Gastroenterología del Perú
Source SetsUniversidad Peruana de Ciencias Aplicadas (UPC)
LanguageSpanish
Detected LanguageEnglish
Typeinfo:eu-repo/semantics/article
Formatapplication/pdf
SourceUniversidad Peruana de Ciencias Aplicadas (UPC), Repositorio Academico - UPC, Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru, 40, 1, 29, 35
Rightsinfo:eu-repo/semantics/openAccess, Attribution-NonCommercial-ShareAlike 4.0 International, http://creativecommons.org/licenses/by-nc-sa/4.0/
Relationhttp://www.scielo.org.pe/scielo.php?pid=S1022-51292020000100029&script=sci_abstract&tlng=en

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