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Estudo de aterosclerose e fatores de risco em pacientes portadores de HTLV-1

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Previous issue date: 2014 / HTLV-1 infection induces a systemic inflammation and occasionally is
associated with co infections. Atherosclerosis is closely related to the inflammatory
process and its progression lasts for decades. Objectives: 1) To study the risk factors
for cardiovascular diseases and atherosclerosis in patients infected by HTLV-1 . 2)
To identify the thickening of the intimal-medial layer. 3) To evaluate the association
between intimal thickening of the intima , the presence of HAM / TSP , ultrasensitive
C-reactive protein and cardiovascular risk factors (age, sex, hypertension ,
hypercholesterolemia , diabetes mellitus and smoking).Study Design: Cross-sectional
observational study. Methods: this study was carried out at the Center for HTLV /
EBMSP, Salvador, Brazil, in the period between April, 2012 to September, 2013 The
outcome of interest was the presence of atherosclerosis. Sociodemographic and
cardiovascular risk factors were evaluated. Results 54 patients were enrolled, with a
mean age (SD) of 57.06 (12.33) years, median (p25 - p75) to 57 (46.8 to 65.0) years
and predominantly composed of women (72.2%), 41% of women and 3% of men had
atherosclerosis. Conclusions: No association was observed between HTLV-1 and
clinical or subclinical atherosclerosis as well as with the risk for cardiovascular
diseases. A positive association between atherosclerosis and age was observed.

Identiferoai:union.ndltd.org:IBICT/oai:www7.bahiana.edu.br:bahiana/78
Date January 2014
CreatorsDória, Glauco Moniz de Aragão
ContributorsCastro Filho, Bernardo Galvão, Durães, André Rodrigues, Garcia, Maristela Magnavita Oliveira, Boa Sorte, Ney Cristian Amaral
PublisherEscola de Medicina e Saúde Pública, Pós-Graduação de Mestrado e Doutorado em Medicina e Saúde Humana, EBMSP, brasil
Source SetsIBICT Brazilian ETDs
LanguagePortuguese
Detected LanguageEnglish
Typeinfo:eu-repo/semantics/publishedVersion, info:eu-repo/semantics/masterThesis
Sourcereponame:Repositório Institucional da Escola Bahiana de Medicina e Saúde Pública, instname:EBM, instacron:EBM
Rightsinfo:eu-repo/semantics/openAccess

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