Background and Objective: To evaluate non-adherence to guideline on rational antibioticotherapy, proportions of hospital infections and empirical treatments in antibioticotherapy, and the need for making intervention to non-rational antibiotics prescriptions.
Design: Observational study of non-adherence to guidelines on rational antibioticotherapy. Analysis of antibiotics prescriptions in tertiary hospital settings.
Setting: 34 wards in tertiary hospital - University hospital at Kaunas University of Medicine.
Main Outcome Measures: Proportions of non-rational treatment.
Results: 331 (29,82%) patient of 1110, received antibiotics prescription. 166 (50.15%) rescriptions for treatment and 165 (49.75 %) for prophylaxis. Empiric treatment 279 (84.29%) cases, 52 (15.71%) treatment cases based on bacteriological analysis. Community infections 111 (67.27%) cases. 206 (62,24%) prescriptions were non-adherent to guidelines rational antibioticotherapy. Correlation of non-adherence with rational antibioticotherapy for hospital and community infections was found as r = 0.43 (P < 0.05) and 0.64 (P < 0.01), correspondingly; and for
empiric treatment and treatment based on bacteriological analysis as r=0.8 (P < 0.01) and 0.06 (P > 0.05), correspondingly.
Conclusions: Empirical treatments in hospital settings comprise high (84%) proportion of cases of antibioticotherapy. Hospital infections comprise high (33%) proportion of infections in hospital settings. Prescription analysis has shown... [to full text]
| Identifer | oai:union.ndltd.org:LABT_ETD/oai:elaba.lt:LT-eLABa-0001:E.02~2006~D_20060711_085346-70588 |
| Date | 11 July 2006 |
| Creators | Bogušis, Evaldas |
| Contributors | Janulis, Valdimaras, Tarasevičius, Eduardas, Kaduševičius, Edmundas, Savickienė, Nijolė, Vainauskas, Paulius, Savickas, Arūnas, Kaunas University of Medicine |
| Publisher | Lithuanian Academic Libraries Network (LABT), Kaunas University of Medicine |
| Source Sets | Lithuanian ETD submission system |
| Language | Lithuanian |
| Detected Language | English |
| Type | Master thesis |
| Format | application/pdf |
| Source | http://vddb.library.lt/obj/LT-eLABa-0001:E.02~2006~D_20060711_085346-70588 |
| Rights | Unrestricted |
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