Made available in DSpace on 2014-06-12T15:07:48Z (GMT). No. of bitstreams: 2 arquivo1579_1.pdf: 825651 bytes, checksum: 2bd41ce7995a8d2e22a72a0273e8dcea (MD5) license.txt: 1748 bytes, checksum: 8a4605be74aa9ea9d79846c1fba20a33 (MD5) Previous issue date: 2004 / A avaliação de programas sociais consiste um importante instrumento estratégico que proporciona informações substantivas sobre as mudanças provocadas no cenário social. No entanto, esse campo, já consolidado em outros países, tem recebido pouca atenção de estudiosos no Brasil, principalmente quando se trata da avaliação de programas implementados por organizações não-governamentais (ONGs). Considerando a dificuldade e necessidade das ONGs em avaliar seus programas, com o intuito principal de conhecer o impacto de sua intervenção, e a importância da ampliação do estudo e da prática da avaliação no Brasil, este estudo apresenta uma experiência empírica de avaliar, mediante uma abordagem participativa, o impacto gerado pelo Programa de Defesa e Efetivação do Direito à Moradia implementado pelo Serviço de Justiça e Paz do Recife

Stroke is the third leading cause of death. Atherosclerosis in the carotid arteries is a risk factor for ischemic stroke. Oxidized low density lipoprotein (LDL) plays a central role in the progression of atherosclerosis. Human paraoxonase 1 (PON1), a high-density lipoprotein (HDL) associated serum esterase/lactonase, protects HDL and LDL from oxidative modifications. Thus, PON1 is protective against the development of atherosclerosis. PON1 gene has two functional coding region (192Q/R and 55L/M) and one promoter region (&amp / #8722 / 107T/C) polymorphism that affect the catalytic efficiency and levels of the enzyme, respectively. In this study, the aim was to determine the importance of PON1 genetic polymorphisms and activity as risk factors for ischemic stroke. The study population was comprised of 172 unrelated adult Caucasian patients with acute hemispheric ischemic stroke and 105 symptom-free controls. Serum and total blood samples were obtained from G&uuml / lhane Military Medical Academy Hospital Neurology Department, Ankara. Hypertension and diabetes were 2 times more common and HDL-C was significantly lower among patients compared to controls. Logistic regression analysis revealed hypertension and smoking to be significant predictors of stroke. Serum PON1 activities towards three substrates, paraoxon (paraoxonase activity / PON), phenyl acetate (arylesterase activity / ARE) and diazoxon (diazoxonase activity), which were measured by spectrophotometric methods, were found to be lower in stroke patients compared to controls. PON and PON/ARE were negatively associated with ischemic stroke by use of logistic regression analysis. PON/ARE was 1.26 times protective against stroke. The frequencies of the risky alleles 192R, 55L and &amp / #8722 / 107T were increased in the patient group. Frequency of the 55L allele of PON1 was significantly increased among patients (0.690) compared to controls (0.628 / P=0.003). Logistic regression analysis revealed PON1 55LL genotype to be associated with a 1.8-fold increase in the risk of ischemic stroke versus control status. Prevalence of triple combined haplotype QRLMTC was significantly lower in stroke patients (4.1%) when compared to controls (11.4% / P=0.019). The combined heterozygote haplotype had around 7 times increased protective effect against stroke in the overall population and 10 times protective effect in the elderly population. The low expressor genotype &amp / #8722 / 107TT was associated with almost 2 times increased risk for stroke in elderly. 192R allele of PON1 represented 1.554 times increased risk for ischemic stroke in hypertensives relative to normotensives. Furthermore, the risk of hypertensive individuals having ischemic stroke was highest in the 192RR group (Odds Ratio / OR=7), followed by 192QR heterozygotes (OR=2.18), and the risk decreased to insignificant levels in 192QQ individuals. 192R allele constituted a 1.55 times increased risk in diabetics. 55L allele was associated with a 1.66 times increased risk of stroke in hypertensives and a 2.6 times increased risk for stroke in diabetics relative to non-diabetics. PON1 &amp / #8722 / 107T allele also represented a 1.35 times risk for stroke in hypertensives.

Made available in DSpace on 2014-06-12T18:05:21Z (GMT). No. of bitstreams: 2 arquivo2577_1.pdf: 1425861 bytes, checksum: 6b478a5b001cb3d32788925e389ba3b6 (MD5) license.txt: 1748 bytes, checksum: 8a4605be74aa9ea9d79846c1fba20a33 (MD5) Previous issue date: 2009 / Coordenação de Aperfeiçoamento de Pessoal de Nível Superior / O desenvolvimento do processo de reforma do metano com dióxido de carbono abordado na presente pesquisa recorre à ação do catalisador de níquel suportado em alumina, disposto em reator de leito fixo com membrana seletiva para hidrogênio associada. Atividade e estabilidade do sistema de níquel (50mg), foram avaliadas através de contato catalisador com uma mistura gasosa de composição em razões molares de alimentação CH4/CO2/Ar (10%/40%/50%), a uma vazão total fixa de 100 cm3/min, operando-se na faixa de temperatura de 1.023 K e 1.073 K, sob pressão de 1,0 bar. A reação de Boudouard (C+CO2→2CO) foi utilizada como base para a regeneração do catalisador de níquel, sob coqueamento, tendo-se observado retomadas de níveis de conversão do metano e de produção de hidrogênio. Operações em reator de membrana, na linha de desenvolvimento do processo, com 2 g de catalisador de níquel (3,31% em massa suportado em alumina), utilizaram uma mistura de reagentes em razões molares CH4/CO2/Ar (40,50%/14,00%/45,50%), com uma vazão total de 110 cm3/min , aplicando-se as temperaturas de 773 K, 823 K e 873 K, sob pressão de 1,0 bar. O processo de reforma seca do metano com dióxido de carbono foi operado em reator de leito fixo de membrana com permeação de hidrogênio, evidenciando uma importante conversão do metano com um rendimento em hidrogênio elevado. A 873 K, sob 1,0 bar de pressão, converteu-se neste sistema 35% de metano rendendo 47% de hidrogênio, significando aumentos de conversão em cerca de 83 % e de rendimento em hidrogênio de mais de 100%, em relação às operações em leito fixo sem permeação. Modelagem e simulações foram elaboradas a partir da cinética já ajustada, permitindo simulações retratando perfis de concentração dos reagentes (CH4 + CO2) e produtos (H2 + CO) com e sem permeação do hidrogênio através da membrana Pd-Ag, destacando-se os efeitos da temperatura

This research aims to comprehend the talentsâ management dynamic and how it can represent a competitive asset in the Information Technology â IT sector. It is based on a theoretical articulation, considering the concepts of business strategy; talentsâ management and competitive assets; dimensions and praxis of the talentsâ management. This exploitive and descriptive research, through case study, was conducted through the application of two models of interviews and a semi-structured questionnaire, made among directors and technical groups from the two biggest companies of the IT sector of the State of CearÃ, one of them in the software development segment and the other in the consulting and training segment. The research involved eight top directors of the two companies, six intermediate managers and fifty-seven professionals of the areas selected for the research. The information was treated on quantitative and qualitative basis. The research allowed us to conclude that the companies studied have their own human resources management in initial phase and there arenât, yet, procedures that allow and maintain the competitiveness and success of these companies, based on talentsâ management. However, there are quite favorable intentions towards attraction, development and maintenance of talents through some actions of the direction. It is believed that the investments and professional practices towards talentsâ management can assure better competitiveness, as evidenced in this research. The environment is favorable to the talentsâ management, a fact proved in some current works being held in the human resources areas of the companies mentioned. / O presente trabalho tem como objetivo compreender a dinÃmica da gestÃo de talentos e como esta constitui diferencial competitivo no setor de Tecnologia da InformaÃÃo− TI. Partindo de uma articulaÃÃo teÃrica em torno dos conceitos de: estratÃgia empresarial; gestÃo de talentos e diferenciais competitivos; dimensÃes e prÃxis da gestÃo de talentos, a pesquisa exploratÃria e descritiva, por meio de estudo de caso, valeu-se da aplicaÃÃo de dois modelos de entrevistas por pauta e um questionÃrio semi-estruturado, aplicados junto a dirigentes e equipes tÃcnicas das duas maiores empresas do setor de TI no Estado do CearÃ, uma no desenvolvimento de software e outra no segmento de consultoria e treinamento. A pesquisa envolveu um nÃmero de oito diretores de topo das duas empresas selecionadas, seis gestores intermediÃrios e cinqÃenta e sete profissionais das Ãreas tÃcnicas selecionadas na pesquisa. As informaÃÃes foram tratadas quantitativa e qualitativamente. A pesquisa permitiu constatar que as organizaÃÃes estudadas possuem prÃticas da gestÃo de recursos humanos em fase inicial e nÃo hÃ, ainda, procedimentos que garantam e sustentem que a competitividade e o sucesso dessas organizaÃÃes repousem na gestÃo de seus talentos. Percebe-se, no entanto, predisposiÃÃes favorÃveis à atraÃÃo, ao desenvolvimento e à retenÃÃo dos talentos por meio de aÃÃes do quadro diretivo e gerencial. Acredita-se que investimentos e prÃticas mais profissionalizadas da gestÃo de talentos possam assegurar maior competitividade, uma vez que foram evidenciadas no estudo consciÃncia favorÃvel à gestÃo de talentos, fato constatado mediante trabalhos em curso nas Ãreas de recursos humanos das empresas pesquisadas.

The radiative &amp / #969 / &amp / #8594 / &amp / #960 / 0&amp / #960 / 0&amp / #947 / , &amp / #961 / &amp / #8594 / &amp / #960 / 0&amp / #960 / 0&amp / #947 / , &amp / #969 / &amp / #8594 / &amp / #960 / +&amp / #960 / &amp / #8722 / &amp / #947 / and &amp / #961 / &amp / #8594 / &amp / #960 / +&amp / #960 / &amp / #8722 / &amp / #947 / decays are studied by adding the effect of vector meson mixing to the amplitude of these decays. For the above decays we consider only &amp / #961 / &amp / #8722 / &amp / #969 / mixing. In addition to the &amp / #961 / &amp / #8722 / &amp / #969 / mixing, we also analyse the contributions coming from different intermediate states to examine the decay mechanism of these decays in a phenomenological framework. For &amp / #969 / &amp / #8594 / &amp / #960 / 0&amp / #960 / 0&amp / #947 / decay, we consider the contributions of the &amp / #961 / -meson and &amp / #963 / -meson intermediate states and of the kaon-loop, and for the &amp / #961 / &amp / #8594 / &amp / #960 / 0&amp / #960 / 0&amp / #947 / decay we calculate the amplitude using the contributions of the &amp / #969 / -meson and &amp / #963 / -meson intermediate states and pion-loop. Moreover, the radiative &amp / #969 / &amp / #8594 / &amp / #960 / +&amp / #960 / &amp / #8722 / &amp / #947 / decay is studied by considering the contributions of &amp / #963 / -meson and &amp / #961 / -meson intermediate states and the decay &amp / #961 / &amp / #8594 / &amp / #960 / +&amp / #960 / &amp / #8722 / &amp / #947 / is investigated by taking into account the contributions of bremmsstrahlung, pion-loop and &amp / #963 / - meson intermediate state amplitude. We also estimate the coupling constant g&amp / #969 / &amp / #963 / &amp / #947 / utilizing the latest experimental value of the branching ratio &amp / #969 / &amp / #8594 / &amp / #960 / 0&amp / #960 / 0&amp / #947 / .