This thesis examines the role of the state in the provision of domestic water supply and sanitation in rural Botswana. The delivery of these services reflects wider international commitment to this sector. Support has been directed through the United Nations' International Drinking Water , , Supply and Sanitation Decade, which has provided member governments with policy recommendations and financial and technical assistance. These recommendations have prescribed the use of bottom-up delivery systems based upon community participation and local government intervention to ensure the achievement of policy objectives. The thesis considers how far the recommendations of the Decade have been implemented in Botswana in providing rural water and sanitation and assesses the extent to which policy objectives have been met. By means of a political economy approach to investigate the role of the state in rural development and fieldwork carried out to investigate the implementation of two specific projects, attention has focussed on the constraints to policy formulation and, implementation in achieving these objectives. It is suggested that the managerial informed prescriptions provided by the Decade are often, inappropriate to the policy arena of specific countries. This is because policy formulation and implementation are determined by factors which are politically motivated and which are not necessarily compatible with managerial or technocratic considerations. It is this inconsistency which has in large part been responsible for the non-attainment of policy objectives. Through detailed field investigations carried out in Botswana, the roles ascribed by the state to different institutions at the local government and community levels in rural policy formulation and implementation are examined in the context of the concept of decentralisation. The suitability of this policy arena for the delivery of the water and sanitation projects is then considered. From the analysis the conclusion, is reached that the context in which rural policy formulation and implementation takes place is not conducive to supporting a bottom-up strategy as prescribed by the Decade. Reasons for this lie in colonial history and in the political and economic circumstances of contemporary Botswana. In consequence, the provision of domestic water supply and sanitation has been affected in two important ways. First, the state has been unwilling to adopt the comprehensive prescriptions offered by the Decade. Second, where it has, constraints rooted in the state's unwillingness to decentralise rural development has prevented the achievement of policy objectives.

Argument: Hypertension is a main contributing risk factor to many cardiovascular diseases and may be the cause or the result of cardiovascular dysfunction. Black Africans, especially, suffer from hypertension because of lifestyle changes that occur during westernisation, which may lead to sympatho-adrenal hyperactivity. Vascular endothelial growth factor-A (VEGF-A) and angiopoietin-2 (Ang-2) are regulators of angiogenesis and are significantly up regulated during states of vascular dysfunction. Levels of angiogenic factors are unknown for African people and may not be the same as levels thus far reported for Caucasians. Aims: The aim of this study is firstly, to determine whether differences exist regarding the levels of VEGF-A and Ang-2 in urbanised compared to rural black Africans and secondly, to determine whether increased levels of VEGF-A and Ang-2 factors are related to hypertension in black Africans. Methodology: This is a sub study that is based upon the Prospective Urban and Rural Epidemiological (PURE) study. Apparently healthy, fasting African men and women (N=272, aged 35 to 50 years) from the North-West province of South Africa were selected by a medical doctor to participate in this study. Groups were stratified according to gender and urbanisation status based upon information derived from sociodemographic questionnaires. Cardiovascular parameters (Omron HEM-757), pulse wave velocity (PWV) (Compiler SP), plasma angiogenic factor levels (ELISA) and anthropometric measures were determined. An independent t-test and Pearson Chi-square test were used to compare urban and rural data, followed by an analysis of covariance (ANCOVA) while correcting for confounders (age, body mass index, physical activity and tobacco usage). ANCOVAs (corrected for confounders) were applied where hypertensive and normotensive groups were compared within the whole group and urbanised groups. Correlations, correcting for confounders, between cardiovascular variables and angiogenic factors were determined within the whole group and urbanised groups. Results and conclusion: Plasma VEGF-A values for all black Africans were very low while the ANG-2 levels were elevated compared to control values for Caucasians (normotensive and hypertensive) in literature. Urbanised men were more overweight and indicated a higher incidence of hypertension (42.47%) and elevated VEGF-A levels, but lower Ang-2 levels compared to rural men. Urbanised women were generally overweight, physically less active and smoked less, but indicated higher diastolic blood pressure (BP), VEGF-A levels and lower PWV compared with their rural counterparts. Ang-2 levels indicate a negative relationship to diastolic BP data in rural women. No relationships between hypertensive individuals and high angiogenic factor levels were uncovered. Conclusive evidence suggested that angiogenic factor levels were affected more by urbanisation than by the state of hypertension. If low levels of VEGF-2 occur, ANG-2 stimulation and properties may be altered, thereby switching ANG-2 from an anti-angiogenic to a pro-angiogenic molecule, inferring blood vessel destabilisation and vascular dysfunction, such as is observed in hypertensive urbanised men. Higher ANG-2 levels may result in Tie-2 receptor down regulation, hence causing VEGF-A levels to be lower. Further study is needed to ascertain this mechanism since Tie-2 receptor activity was not determined in this study. / Thesis (M.Sc. (Physiology))--North-West University, Potchefstroom Campus, 2009.

Argument: Hypertension is a main contributing risk factor to many cardiovascular diseases and may be the cause or the result of cardiovascular dysfunction. Black Africans, especially, suffer from hypertension because of lifestyle changes that occur during westernisation, which may lead to sympatho-adrenal hyperactivity. Vascular endothelial growth factor-A (VEGF-A) and angiopoietin-2 (Ang-2) are regulators of angiogenesis and are significantly up regulated during states of vascular dysfunction. Levels of angiogenic factors are unknown for African people and may not be the same as levels thus far reported for Caucasians. Aims: The aim of this study is firstly, to determine whether differences exist regarding the levels of VEGF-A and Ang-2 in urbanised compared to rural black Africans and secondly, to determine whether increased levels of VEGF-A and Ang-2 factors are related to hypertension in black Africans. Methodology: This is a sub study that is based upon the Prospective Urban and Rural Epidemiological (PURE) study. Apparently healthy, fasting African men and women (N=272, aged 35 to 50 years) from the North-West province of South Africa were selected by a medical doctor to participate in this study. Groups were stratified according to gender and urbanisation status based upon information derived from sociodemographic questionnaires. Cardiovascular parameters (Omron HEM-757), pulse wave velocity (PWV) (Compiler SP), plasma angiogenic factor levels (ELISA) and anthropometric measures were determined. An independent t-test and Pearson Chi-square test were used to compare urban and rural data, followed by an analysis of covariance (ANCOVA) while correcting for confounders (age, body mass index, physical activity and tobacco usage). ANCOVAs (corrected for confounders) were applied where hypertensive and normotensive groups were compared within the whole group and urbanised groups. Correlations, correcting for confounders, between cardiovascular variables and angiogenic factors were determined within the whole group and urbanised groups. Results and conclusion: Plasma VEGF-A values for all black Africans were very low while the ANG-2 levels were elevated compared to control values for Caucasians (normotensive and hypertensive) in literature. Urbanised men were more overweight and indicated a higher incidence of hypertension (42.47%) and elevated VEGF-A levels, but lower Ang-2 levels compared to rural men. Urbanised women were generally overweight, physically less active and smoked less, but indicated higher diastolic blood pressure (BP), VEGF-A levels and lower PWV compared with their rural counterparts. Ang-2 levels indicate a negative relationship to diastolic BP data in rural women. No relationships between hypertensive individuals and high angiogenic factor levels were uncovered. Conclusive evidence suggested that angiogenic factor levels were affected more by urbanisation than by the state of hypertension. If low levels of VEGF-2 occur, ANG-2 stimulation and properties may be altered, thereby switching ANG-2 from an anti-angiogenic to a pro-angiogenic molecule, inferring blood vessel destabilisation and vascular dysfunction, such as is observed in hypertensive urbanised men. Higher ANG-2 levels may result in Tie-2 receptor down regulation, hence causing VEGF-A levels to be lower. Further study is needed to ascertain this mechanism since Tie-2 receptor activity was not determined in this study. / Thesis (M.Sc. (Physiology))--North-West University, Potchefstroom Campus, 2009.

No description available.

La présente recherche démontre une reconnaissance progressive des impacts du phénomène de mondialisation et d’urbanisation rapide sur les femmes et les filles dans les villes du Sud. La violence envers les femmes et les filles en milieu urbain est de plus en plus reconnue comme un enjeu de développement par les organisations internationales. Afin d’explorer et d’analyser cet enjeu, quatre théorisations visant une réduction de la violence envers les femmes et les filles à faible revenu en milieu urbain sont exposées en insistant sur la dimension de genre. L’étude de cas de Jagori, une organisation indienne, permet de cerner les liens entre ces théorisations (droits humains, sécurité humaine, accès direct aux services et droit à la ville) et les interventions sur le terrain. La documentation et les entretiens avec des personnes-clés ont permis de démontrer que l’utilisation plurielle de ces théorisations se fait graduellement et de façon stratégique. La structure d’opportunité politique et la structure de mobilisation exposent les différents facteurs qui viennent influencer le lien théorisation-intervention. Dans le cas de Jagori, ces structures complexifient la pratique et amènent des changements importants dans leurs interventions tout en lui conférant une plus grande visibilité auprès des acteurs influents. L’accès aux ressources matérielles et symboliques accordé par l’État et les organisations internationales est indispensable et fait en sorte que Jagori doit arrimer ses interventions avec les discours et les priorités établies par ces acteurs.

Ph. D.--Katholieke Universiteit van Nijmegen, 1990.

Diss.--Philosophische Fakultät--München--Ludwig-Maximilians-Universität, 1987. / Bibliogr. p. 329-348. Index.

Texte remanié de: Th. doct.--Ethnol.--Bordeaux 2, 1995. / Mention parallèle de titre ou de responsabilité : Euskal kultura ta hiritartzea Hazparnen. La couv. porte : "société, économie, histoire, langues, animation..." En appendice, choix de documents. Bibliogr. p. 225-234.

Thèse d'État--Paris 10, 1975. / En appendice, choix de documents. Bibliogr. p. 435-455.

Th. 3e cycle--Urban.--Paris 8, 1987.