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Computer Aided Drug Design from a Series of GSK3b Inhibitors: Advancements Towards the Treatment of Bipolar DisorderBoesger, Hannah 28 April 2022 (has links)
No description available.
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Advances in the Pharmacological Treatment of Bipolar Affective DisordersMcCabe, Susan 01 January 2003 (has links)
TOPIC. Advances in the psychopharmacologic treatment of bipolar affective disorders (BPAD). PURPOSE. To increase advanced practice nurses' ability to match prescribing practices with known etiological factors and the neurobiology of this complex set of disorders. SOURCES. Published literature. CONCLUSIONS. A wide array of pharmacological agents exist that can be useful to manage BPAD symptoms. APRNs play a critical role in helping patients and their families to use these drugs effectively.
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Clinical Inquiries. Which Tool is Most Useful in Diagnosing Bipolar Disorder in Children?Stephens, Mary M., Bajaj, Jaya, Wallace, Rick, Zolotor, Adam 01 January 2007 (has links)
In Tennessee, several medical library outreach projects have involved collaborative work with health-care professionals, public librarians, consumers, faith-based organizations and community service agencies. The authors are medical librarians who worked as consultants, trainers and project directors to promote health literacy using PubMed medline and other health information resources in the several funding projects described here. We explain the programmes briefly, focusing on lessons learned and suggestions for those who follow us.
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The Effect of Marijuana Craving on Brain Activation and Recognition Memory in Healthy and Bipolar AdolescentsBurciaga, Joaquin January 2012 (has links)
No description available.
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The Effect of Marijuana Craving on Brain Activation and Recognition Memory in Healthy and Bipolar AdolescentsBurciaga, Joaquin January 2012 (has links)
No description available.
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A Meta-Analytical Study of Pediatric Bipolar Disorder: Symptomology and ComorbidityWalter, April January 2009 (has links)
No description available.
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How does Bipolar and Depressive Diagnoses Reflect in Linguistic Usage on Twitter : A Study using LIWC and Other Tools / Hur Reflekterar Bipolära respektive Depressiva Diagnoser Lingvistisk Användning på TwitterOlsson, Viktor, Lindow, Madeleine January 2018 (has links)
Depression and bipolar disorder are two mental disorders which left untreated can have a devastating effect on a persons life as they are considered both chronic and disabling. Seeking help is often a big step that can be procrastinated for years, and misdiagnosis is a very common problem once contact with psychiatric care has finally been established. This paper investigates the correlation between posting patterns on Twitter and suffering from these diagnoses. For each day of the past year we quantify cues for emotional intensity and polarity, involvement with their social network and activity as well as metrics previously shown to be associated with depression. A number of statistical tests, including Anova, t-testing and Covariance analysis, are then constructed and fitted over our data. Our results show a significant difference between our groups in affective language use tied to emotional polarity as well as an elevated use of first person personal pronouns for both the depressed and bipolar group. These findings indicate strongly that our approach is valid for finding cues about mental illness, however the strong limitations in our data collections approach needs to be addressed in order for our results to have real scientific merit. This study is motivated by the need for finding predictive models for mental disorders, and to better understand the disorders themselves. Predictive models can be helpful for proper diagnosis by a clinical psychologist as well as for helping more people seek treatment. / Depression och bipolär sjukdom är två psykiska sjukdomar som obehandlade kan ha en förödande effekt på en persons liv eftersom de anses både kroniska och förlamande. Att söka hjälp är ofta ett väldigt stort steg som kan prokrastineras i flera år, och dessutom är feldiagnosticering ett väldigt stort problem när en kontakt med psykiatrin väl har upprättats. Denna rapport undersöker korrelationen mellan inläggsmönster på Twitter och dessa två diagnoser. Vi kvantifierar varje enskild dag av det senaste året i termer av kännetäcken för en människas emotionella intensitet och polaritet, engagemang med sitt sociala nätverk och aktivitet, såväl som parametrar som i tidigare forskning visat sig associerade med depression. Vi använder sedan statistiska modeller såsom variansanalys, t-test och kovariansanalys över vår data. Våra resultat visar på en signifikant skillnad mellan våra grupper i affekterat språkbruk och hur det kopplas till emotionell polaritet. Vi visar även på ökat användande av pronomen i första person singular hos våra bipolära och deprimerade grupper. Dessa resultat tyder på att vår metod är giltig för att hitta indikationer för mental ohälsa, men begränsningar i vår datainsamling behöver adresseras innan våra resultat kan ha riktig vetenskaplig betydelse. Den här studien är motiverad av behovet av att finna modeller med prediktiv kraft för psykisk ohälsa, och att bättre förstå depression och bipolar sjukdom som helhet. Prediktiva modeller kan vara hjälpsamma för korrekt diagnossättning av en klinisk psykolog samt att hjälpa individer att söka behandling.
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bipolar[i].discuss();Walker, Megan Anna Hein 17 September 2013 (has links)
This MFA thesis uses the medium of computer language to explore the chaos underlying Bipolar I Disorder, an enigmatic and disruptive illness. Using creative coding to generate a series of abstract systems representing human traits, I explore the common truth that pervades the seemingly randomness of mental illness: we all break the same. / Master of Fine Arts
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Impaired risk avoidance in bipolar disorder and substance use disordersGold, Alexandra K. 26 January 2023 (has links)
Comorbid substance use disorders (SUDs) are highly prevalent in bipolar disorder (BD), with up to 60% of individuals with BD developing an SUD at some point in their lifetime. In addition, research suggests that individuals with this comorbid presentation (BD+SUD) typically have worse outcomes -- including increased mortality, morbidity, and functional impairment -- than individuals with BD alone. Given the increased illness burden associated with BD+SUD, I conducted a systematic review evaluating existing psychosocial treatments for individuals with these comorbidities. Results from this review indicated that no existing psychosocial treatments for these comorbid conditions effectively target both the substance use and mood domain of symptoms. An alternative path to treatment development is to identify mechanisms that underlie BD+SUD that can subsequently be targeted in treatment. Accordingly, I evaluated impairments in risk avoidance (a tendency to engage in a persistent pattern of problematic behaviors despite negative outcomes resulting from such behaviors) as a potential mechanism underlying negative illness outcomes in BD+SUD. Participants with BD (n = 45) or BD+SUD (n = 31) in a relatively euthymic mood state completed clinical risk behavior assessments, laboratory-based risk avoidance assessments, and neurocognitive assessments in a single study session. I hypothesized that the BD+SUD group would exhibit increased clinical risk behaviors, increased impairments on laboratory-based measures of risk avoidance, and increased deficits on neurocognitive assessments relative to the bipolar disorder alone group. Contrary to my hypotheses, results indicated a lack of notable between-group differences in clinical risk behaviors, laboratory-based risk avoidance assessments, and neurocognitive assessments, with the exception of self-reported executive dysfunction which was elevated among individuals with BD+SUD. Collapsing across group, I found that increased discounting of delayed rewards, older age, and an earlier age of (hypo)mania onset predicted increased clinical risk behaviors. These findings underscore the potential importance of delay discounting as a mechanistic target for reducing clinical risk behaviors among individuals with BD both with and without comorbid SUDs. I also discuss the neurocognitive correlates of delay discounting and interventions for addressing delay discounting as potential new directions for treating the disability associated with BD.
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Att vara med mamma känns som att vara på andra sidan jorden : En kvalitativ litteraturstudie om barn som växt upp med en förälder som är diagnostiserad med bipolär sjukdom / Being with mom feels like being on the other side of the world : A qualitative literature study about children who have grown up with a parent that is diagnosed with bipolar disorderDidriksson, Matilda January 2023 (has links)
Background: Bipolar disorder is a chronic mental health condition that lasts for a lifetime. The condition causes episodes of mani, hypermania and depression. Between the episodes there is a period in wich the individual if free of symtoms. Bipolar disorder is divided into two types, Bipolar 1 disorder and Bipolar 2 disorder. The condition can not be cured but the symtoms can be treated. Heredity and enviroment are estimated to be contributing factors for the development of the condition. Approximately 23% of all children in the world are estimated to have grown up with a parent with psychiatric disease. Aim: In this qualitative literature study, children's experience of growing up with a parent diagnosed with Bipolar disorder was studied. Method: The method that was used was a non-systematic literature review with an integrated analysis. Result: The analysis resulted in four themes, The child's experience of its parent, Social network, When the parent is in need of inpatient care and Stigmatization & attitudes. Eight subthemes were presented that describes the experience of living with a parent who is diagnosed with Bipolar disorder. Conclusion: Based on the collection of the children's experiences from their childhood with a parent that is diagnosed with Bipolar disorder, it is clear that the child is affected by their parents mental illnes. It is important for the children to have a social network and be able to talk about their feelings and experiences, instead of being forced by family and society to be silenced about their parent's mental illnes. / <p>Syfte och frågeställning var inte placerade enligt mallen. </p>
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