We report a de novo dup(X)(q23→q26) in a 3-year-old girl with growth retardation, developmental delay, and minor anomalies. X-inactivation in lymphocytes by BRDU labeling showed the abnormal X was late replicating. The androgen receptor assay (HAR) demonstrated a skewed methylation (88.8%) of the paternal allele and a 11.2% methylation of the maternal allele. These data, which suggest the duplication was paternally inherited, are the first parental-origin identification of a duplication Xq. The mild phenotype of the patient may be related to the size and region of the duplication, the low percentage of a dup(X) active detected by the HAR assay, or a combination of these mechanisms. .

Title: Impact of country of origin on consumer purchase intention amongPakistani customers buying fashion clothes onlineLevel: Master Programme in Business Administration (MBA): Business ManagementAuthor: Hafiz Azhar Ahmed KhanSupervisor: Dr. Ehsanul Huda Chowdhury & Dr. Katarina ArbinExaminer: Dr. Daniella FjellströmDate: March 2022Aim: The research study investigates the impact of country of origin on consumerpurchase intention through consumer preference for Pakistani consumers buying fashioncloth online.Method: The study is using a quantitative research method Data has been collectedthrough a questionnaire that 157 respondents answered. Results were analyzed throughSPSS.Results & Conclusions: The results of this study show that country of origin andconsumer purchase intention has a significant relationship with each other, andconsumer preference mediates the relationship between the variables. Furthermore, itdepicts that when consumers take the country of origin positively, their purchaseintention also becomes positive and vice versa. Further, it has also been found thatconsumer preference builds a strong relationship between a country of origin andpurchase intention.Contribution of the thesis: The current idea has contributed to research related to thecountry of origin because there is no specific study in the Pakistani context which hasstudied the impact of country of origin on consumer preference and how preference canmediate the country of origin‘s effect on consumer purchase intention. In both ways,current research has explained how Country of origin is positively changing preferencesof fashion clothes, and mediation of consumer preference is also proven. It extends theliterature on the Country of origin concerning new context and new mediating variables.It makes the findings of the theory of planned behavior more significant for extrinsiciicues. It also guides managers to schedule their ads and marketing strategies to makethem more successful and competitive.Suggestions for future research: Future researchers should take the current research tothe next level and identify more outcomes of country of origin, such as how it can betterbrand equity or Sales volume. Furthermore, comparative studies can be conducted inwhich a developing and developed country can be specified. Responses for bothcountries should be obtained separately, and then differences can be brought to see themultilevel impact of country of origin. Another suggestion for future research is toconduct a comparative study between online and physical shoppers as the currentresearch was limited to online fashion clothes only

The arcsine distribution looks at the fraction of time one player is winning in a fair coin toss game and has been studied for over a hundred years. There has been little further work on how the distribution changes when the coin tosses are not fair or when a player has already won the initial coin tosses or, equivalently, starts with a lead. This thesis will first cover a proof of the arcsine distribution. Then, we explore how the distribution changes when the coin the is unfair. Finally, we will explore the distribution when one person has won the first few flips.

The influences that crime control, due process factors, and individual demographic characteristics have on the criminal trial outcomes of accused arsonists was unknown. Absent this knowledge, it was not clear if public policy ensures justice for the accused, particularly for the disadvantaged. The purpose of this quasi-experimental study was to investigate, using Packer's due process and crime control model as the theoretical framework, the relationship between time to trial, number of defense and prosecution witnesses, access to fire origin and cause experts, legal representation type, age, race, education, and gender and criminal arson case outcomes. A sample size of 165 archival court records of those accused of arson from 2011-2015 were analyzed using Packer. According to the results of the logistic regression models, there was a significant relationship (p < .05) between trial outcomes and the use of fact witnesses by the defense and by the prosecution.This relationship moved the pendulum toward crime control for the selected population. The ordered logistic model explained 6.9% of the variation in the criminal case outcomes. Policymakers can use the results of this study to inform criminal justice policy and to prioritize funding to assure fairness and social justice for the accused. Arson defendants and their counsel can use the results to prepare their defense to assure their social justice while prosecutors can use the results to better inform their decisions to assure the legal and factual guilt of the defendant. Future research is needed to provide a clearer understanding of the role that other variables play in the outcome for the population.

As part of a U.S. Geological Survey study in Juab Valley in central Utah from 1991 to 1994, the chemistry of ground - and surface -water samples was determined. Total dissolved solids in the ground water of southern Juab Valley have historically been higher , in general, than ground water in other areas of Utah . Total dissolved solids for ground-water samples from this study ranged from 623 to 3,980 milligrams/liter. High-sulfate chemical data of previous studies suggested that the major source of ground-water salinity is the dissolution of gypsum (hydrous calcium sulfate ) from the Arapien Shale. Sulfur-34 to sulfur- 32 isotopic ratio data have confirmed that dissolved Arapien Shale is the major source of salinity in southern Juab Valley water. This thesis study of southern Juab Valley had four main objectives: 1) define the present chemistry of the ground and surface water; 2) qualitatively determine the mineralogy of the Middle Jurassic Arapien Shale; 3) determine the major sources of salinity; and 4) determine the main flow path in the ground-water system. Chemical data show that the water in southern Juab Valley is predominantly of a calcium-magnesium-sulfate-bicarbonate composition. X-ray diffraction determined the mineralogy of the Arapien Shale as primarily calcite and quartz. Mineralogy of the acid-insoluble residue is illite, chlorite, quartz, and a trace of feldspar. Based on chemical, isotopic, and simple salt weight percent data, dissolution of gypsum is the major source of salinity in southern Juab Valley water. Using the chemical and isotopic data as input , a mass balance computer software program (NETPATH) helped to determine that the gypsum is derived from the Arapien Shale . NETPATH and the potentiometric surface map helped to define the main ground-water flow path as southwest across southern Juab Valley, from Chicken Creek in the San Pitch Mountains on the east side of the valley toward Chick Creek Reservoir in the southwest part of the valley.

The current study presents findings regarding marital preparation for individuals in great marriages. Data from a national qualitative study of individuals in self-identified great marriages were used. Thirty-eight individuals were identified as being married for 20 years or less, and therefore, chosen as the subsample for the current study. Their rich, narrative responses were analyzed and coded, using a qualitative method, to identify what marriage preparation occurred for these couples prior to marriage and contributed to their successful marriages. Findings from this research provide helpful, descriptive data on the experiences and socialization of individuals that influenced their choice in a marriage partner as well as later marital success. Implications for practitioners, researchers, and individuals are provided.

The conventional methods of determining the Origin-Destination (O-D) trip tables involve elaborate surveys, such as home interviews, requiring considerable time, manpower and funds. To overcome this drawback, a number of theoretical models that synthesize O-D trip tables from link volume data have been developed in the past. The focus of this research was on two of these models, namely, The Highway Emulator (THE) and the Linear Programming (LP) models. These models use target/seed tables for guiding the modeled trip tables. In an earlier research effort conducted by Virginia Tech Center for Transportation Research, potential was noted for enhancing these models' performances by using a superior target/seed table. This research study exploits the readily available socio-economic/census data and link volume information and proposes a methodology for obtaining improved target/seed tables, by performing the trip generation and trip distribution steps. This table was provided as target to THE and LP models, and their performances evaluated using Pulaski town as case study. In addition to measuring the closeness of the output tables to surveyed tables and their capability to replicate observed volumes, their improvements over the case when a structural table is used as target was also studied. Tests showed that the use of the superior target/seed table significantly improved the performance of the LP model. However, for THE, mixed trends are seen in terms of different measures of closeness. The sensitivity of the user parameter to place certain degree of belief on the target/seed table for LP model was also analyzed. / Master of Science

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Isotopic assays, including stable carbon, stable oxygen, and radiogenic strontium were measured for 37 individuals from the Talgua cave ossuaries to understand human movement and mortuary practice during Formative Period Honduras. Likelihood assignment models demonstrated that the individuals had diverse childhood geographic origins within the surrounding valleys. This shows that different kin or ethnic groups from diverse geographic origins were utilizing the ossuaries. Five possible ‘non-local’ individuals were identified from the radiogenic strontium and stable oxygen isotope datasets, suggesting minimal human movement into northeast Honduras from outside Lower Central America. The low number of ‘non-local’ individuals at Talgua Caves also suggests that trade items were acquired by down-the-line exchange processes rather than through a long-distance trade connection. This type of trade network and bioarchaeological evidence of limited ‘non-local’ individuals at Talgua Caves suggests the surrounding region was culturally distinct from Mesoamerica during the Formative Period.