因應全球科學園區發展的潮流，我國於1980年設立第一個科學園區－新竹科學園區（簡稱竹科），經過多年的努力，已成為世界上發展成功的科學園區之一，美國商業週刊稱之為「台灣的矽谷」，是台灣經濟發展的重要命脈，也是維持我國競爭力於不墜之重要關鍵因素。而為執行園區管理業務，由行政院國家科學委員會設立「科學工業園區管理局」，辦理相關工作及提供各項服務。 　　本研究採用文獻探討法及深度訪問法等二種研究方法，試圖就科學園區危機類型做一分類，並以危機管理四階段理論及運用「全盤型弱點管理」觀點，檢視科學工業園區管理局危機管理機制之運作，找出其脆弱度，透過跨域聯防相關理論、兩個案例經驗借鏡及相關人員深度訪談資料之歸納分析，試圖提出建構科學園區危機管理跨域聯防機制之策略，並輔以政策工具理論，作為可能面臨困境之對策，以提供科學工業園區管理局及相關單位參考。 / To meet the trend of global science parks, the first science park in Taiwan, Hsinchu Science Park (HSP), was established in 1980. After endeavored for years, it has become one of the most successful science parks in the world, which Business Week called, “Taiwan’s Silicon Valley.” It is a very important lifeline of Taiwan economic development, and a key factor of maintaining Taiwan’s competitive advantage. Under the jurisdiction of the National Science Council, the Science Park Administration (SPA) is given the responsibility of developing, operating and managing the park. This study adopts two research ways: literature review method and interviewing method, and attempts to classify the crisis type of the science park. Based on the four steps theory of crisis management and the point of view of “Comprehensive Vulnerable Management,” it is to inspect the operation of crisis management of Science Park Administration to find out its vulnerability. Through the generalization and analysis of the related theory of joint defense across boundary, two cases review and related further interview, it attempts to set a strategy for joint defense across boundary of the science park, assists with policy instruments theory to offer a solution for coming difficulty, and to be a reference for Science Park Administration and related organizations.