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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
1

高社會焦慮者在增加聯結的自我參照靜息態功能網絡初探 / Hyper-Connectivity of Self-Referential Resting-State Networks in Individuals with High Social Anxiety

李炯德 Unknown Date (has links)
本研究的主要目的在於運用靜息態功能性磁振造影技術來探討高社會焦慮的自我參照處理腦區的功能聯結。根據Clark和Wells(1995)的模型,高社會焦慮者的負向自我心象只透過自我相關的在線索來建構;然而根據Rapee和Heimberg(1997)的模型則假設高社會焦慮者還會納入他人外在訊息,做自我與他人參照訊息的處理。本研究企圖透過神經影像的發現來檢測上述兩個模型。 本研究篩選出四十名大學生分為高社會焦慮組與低社會焦慮組,所有受試者都會進行靜息態功能性磁振造影的掃描,並使用MPFC、PCC、ACC、VMPFC、DMPFC作為種子進行全腦的功能聯結分析並獲得功能聯結圖譜做比較。 研究結果發現高社會焦慮者的MPFC、PCC、ACC都有增加的功能聯結,顯示他們比一般人更容易做自我參照處理,而VMPFC、DMPFC同時有增加的功能聯結,代表高社會焦慮者的自我參照處理除了自我內在的相關訊息外,還會包含他人外在相關訊息的處理,研究結果較支持Rapee和Heimberg(1997)的說法。最後並提出本論文研究限制,與對社會焦慮症的臨床理論與實務上之建議。 / The purpose of the present study was to utilize the resting-state functional magnetic resonance imaging(RS-fMRI) technique to investigate the brain regions in functional connectivity of self-referential processing in socially anxious individuals. According to Clark and Wells’ (1995) view, socially anxious individuals were hypothesized to construct their negative self-image with self-related internal information. However, according to Repee and Heimberg’ s (1997) model, they supposed that socially anxious individuals also brought other-related external information to make other-related external information self-referential and other-referential be processed. The present study was designed to use finding of neuroimaging to examine the two models Forty undergraduate students were assigned to either high or low social-anxiety group. All subjects were asked to be scanned with RS-fMRI. MPFC, PCC, ACC, VMPFC, DMPFC were used as seeds to proceed the whole-brain functional connectivity analysis and acquired functional connectivity maps for comparison. The results revealed that functional connectivity of MPFC, PCC, ACC of high social anxiety group increased, it displayed that they were more easily to do self-referential processing. Besides, functional connectivity of VMPFC and DMPFC also increased simultaneously, which means that the self-referential processing of high social anxiety group not only included self-related internal information but also included other-related external information. The result supported Repee and Heimberg’ s model. The limitations of this study and the suggestions for the theories and clinical treatment of social anxiety disorder were advanced in the end.

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