Die Broschüre berichtet über Entwicklung und Erprobung nutzungsintegrierter Schutzmaßnahmen für gefährdete Vogelarten. Alle Maßnahmen sind grundsätzlich geeignet, die Bestände von Rebhuhn, Kiebitz und Feldlerche positiv zu beeinflussen. Die Akteure wurden für Belange des Artenschutzes sensibilisiert, ihre Zusammenarbeit gestärkt. Für Landwirte, Naturschützer, Jäger und Behörden stellt die Publikation eine Grundlage dar, um Schutzmaßnahmen umzusetzen.

No description available.

Prediction of ground settlements have always been a big challenge for the engineers that are responsible for the design of subway tunnel projects. Since ground settlement is a crucial concept directly affecting the successfulness of a project, it must be taken seriously and should be accurately estimated. Consolidation settlements in the close proximity of Ulus-Ke&ccedil / i&ouml / ren Subway project due to groundwater drainage is the focus of this study. In this sense, the necessary data about the project characteristics and the site conditions were collected thru project descriptions and the geotechnical investigations conducted at the project site. Utilizing the generated database analytical calculations were carried out to predict the settlements. Upon completion of this stage of analysis several of the locations were numerically modeled for further investigation. Numerical analysis was conducted at four sections by using Plaxis, to determine the amount of expected displacements and the resulting groundwater situation. Despite of the differences between these two methods the resulting settlement estimations displayed consistency.

- / -

This thesis offers an examination of egg-collecting, which was a very popular pastime in Britain from the Victorian era well into the twentieth century. Collectors, both young and old, would often spend whole days and sometimes longer trips in a wide variety of different habitats, from sea shores to moorlands, wetlands to craggy mountainsides, searching for birds’ nests and the bounty to be found within them. Once collectors had found and taken eggs, they emptied out the contents; hence, they were really eggshell collectors. Some egg collectors claimed that egg-collecting was not just a hobby but a science, going by the name of oology, and seeking to establish oology as a recognised sub-discipline of ornithology, these collectors or oologists established formal institutions such as associations and societies, attended meetings where they exhibited unusual finds, and also contributed to specialist publications dedicated to oology. Egg-collecting was therefore many things at once: a culture of the British countryside, from where many eggs were taken; a culture of natural history, taking on the trappings of a science; and a culture of enthusiasm, providing a consuming passion for many collectors. By the early twentieth century, however, opposing voices were increasingly being raised, by conservation groups and other observers, about the impact that egg-collecting was having on bird populations and on the welfare of individual birds. By mid-century the tide had turned against the collectors, and egg-collecting in Britain was largely outlawed in 1954, with further restrictions imposed in 1981. While many egg collections have been lost or destroyed, some have been donated to museums, including Glasgow Museums (GM), which holds in its collections over 30,000 eggs. As a Collaborative Doctoral Award involving the University of Glasgow and GM, the project outlined in this thesis aims to bring to light and to life these egg collections, the activities of the collectors who originally built them, and the wider world of British egg-collecting. By researching archival material held by Glasgow Museums, published specialist egg-collecting journals and other published sources, as well as the eggs as a material archive, this thesis seeks to recover some of the practices and preoccupations of egg collectors. It also recounts the practical activities carried out during the course of the project at GM, particularly those involving a collection of eggs newly donated to the museum during the course of this project, culminating in a new temporary display of birds’ eggs at Glasgow Museums Resource Centre.

The present study argues that a series of programmatic additions were made to the oracles concerning the nations in Isa 13-23 during the late-exilic period by the same circle of writers who were responsible for Isa 40-55. These additions were made to create continuity between the ancient oracles against the nations from the Isaiah tradition and the future fate of the same nations as the late-exilic redactor(s) foresaw. The additions portray a two-sided vision concerning the nations. One group of passages (14:1-2; 14:32b; 16:1-4a; 18:7) depicts a positive turn for certain nations while the other group of passages (14:26-27; 19:16-17; 23:8-9, 11) continues to pronounce doom against the remaining nations. This double-sided vision is set out first in Isa 14 surrounding the famous taunt against the fallen tyrant. 14:1-2, before the taunt, paints the broad picture of the future return of the exiles and the attachment of the gentiles to the people of Israel. After the taunt and other sayings of YHWH against his enemies, 14:26-27 extends the sphere of the underlying theme of 14:4b-25a, namely YHWH's judgement against boastful and tyrannical power(s), to all nations and the whole earth. The two sides of this vision are then applied accordingly to the rest of the oracles concerning nations in chs 13-23. To the nations that have experienced similar disasters as the people of Israel, words of hope in line with 14:1-2 were given. To the nations that still possessed some prominence and reasons to be proud, words of doom in line with 14:26-27 were decreed. Only later in the post-exilic period, for whatever reason, be it changed international political climate or further spread of the Jewish diaspora, was the inclusive vision of 14:1-2 extended even to the nations that were not so favourably viewed by our late-exilic redactor (19:18-25; 23:15-18).

Protein Methyltransferasen sind oftmals fehlreguliert in Tumorzellen und stellen potenzielle Ziele in der Krebstherapie dar. Das SET und MYND Domain enthaltene Protein 2 (SMYD2) wurde als potenzielles Onkogen beschrieben und eine Überexpression korreliert mit einer schlechten Prognose. Für SMYD2 wurden verschiedene Substrate beschrieben u.a. Histon H3 und der Tumorsuppressor p53, allerdings ist die Biologie dieses Enzymes kaum verstanden. Durch die Entwicklung einer Testsubstanz zur spezifischen Hemmung von SMYD2 könnte ein möglicher therapeutischer Nutzen besser untersucht werden. Hierfür wurde ein zellulärer mechanistischer Test zur Messung der SMYD2 Aktivität mittels eines methylierungs-spezifischen Antikörpers etabliert. Mit Hilfe dieses Tests wurde BAY-598 als selektiver und potenter zellulärer Hemmer für SMYD2 identifiziert. Im weiteren Verlauf dieser Arbeit wurden mittels eines Proteomansatzes nach SMYD2 Überexpression hunderte neue zelluläre Lysinmethylierungen identifiziert. Hierbei wurde das AHNAK Protein als neues SMYD2-Substrat identifiziert und validiert. Die AHNAK Methylierung konnte in verschiedenen Zelllinien und im Muskelgewebe von Mäusen nachgewiesen werden. Im letzten Teil der Arbeit wurde die spezifische Testsubstanz BAY-598 genutzt, um verschiedene in der Literatur aufgekommene Hypothesen zur SMYD2 Funktion zu testen. Die vorliegende Arbeit hat dazu beigetragen die potente und selektive SMYD2 Testsubstanz BAY-598 zu entwickeln. Außerdem wurde mit AHNAK ein neues SMYD2 Substrat identifiziert und validiert. Die Relevanz des SMYD2 Enzymes und der AHNAK Methylierung erfordert weitere Forschungsarbeit, die durch die Bereitstellung der spezifischen Testsubstanz BAY-598 deutlich verbessert werden sollte. / Protein methyltransferases are often misregulated in tumor cells and display a potential target for cancer therapy. The SET and MYND domain containing protein 2 (SMYD2) was described as a potential oncogene and overexpression correlated with a worse prognosis. Several substrates for SMYD2 had been described among them histone H3 and p53. However, the biology of SMYD2 is poorly understood. By developing a small molecule inhibitor of SMYD2 its therapeutic role could be better evaluated. Therefore, a cellular mechanistic assay was developed using a methylation specific antibody. With that assay BAY-598 was identified as a potent and selective cellular inhibitor of SMYD2. In the following a proteomic approach revealed hundreds of novel cellular lysine methylation sites in SMYD2 overexpression cells. Among these AHNAK protein was validated as a novel SMYD2 substrate, which was present in several cell lines as well as in muscle of mice. Finally, BAY-598 was used to test several hypothesized functions of SMYD2 in different cell line models. Taken together, the current work strongly supported the development of the probe inhibitor BAY-598 and the discovery of AHNAK as a novel SMYD2 methylation substrate. The relevance of SMYD2 and AHNAK methylation needs further investigation, which should be supported by BAY-598.

Der Atlas behandelt 213 aktuelle und ehemalige Brutvogelarten in Sachsen. Hiervon werden 177 Arten ausführlich mit den Schwerpunkten Verbreitung, Lebensraum, Brutbestand, Phänologie und Brutbiologie sowie Gefährdung und Schutz besprochen. Aus drei Zeitebenen liegen landesweite Bearbeitungen der Brutvogelfauna auf Rasterbasis vor. Die Ergebnisse ermöglichten es, in detaillierten Karten Bestandstrends darzustellen und Veränderungen von Verbreitung und Häufigkeit nachzuvollziehen. 293 Fotos veranschaulichen die Vielfalt der Vogelarten und zeigen ihren typischen Lebensraum.

Species diversity varies dramatically across the surface of the Earth. A key step in the accumulation of species diversity is the ability of species to coexist in biological communities. Thus, identifying the mechanisms underlying community assembly is a major challenge for ecologists seeking to explain patterns in species diversity and composition. Recently some consensus has been reached on the set of processes that influence community assembly: speciation, demographic stochasticity, niche-based fitness trade-offs among species and dispersal. However, it is unclear how the importance of a particular process changes with spatial scale, which interactions exist among processes at large spatial scales and the extent to which niche-based resource partitioning among species explains differences in diversity among communities. Neotropical birds offer an ideal opportunity to address these uncertainties because of their high diversity and the existence of detailed information on their evolutionary history and ecology. In this thesis, I first use trait and phylogenetic metrics of community structure to show that both habitat filtering and interspecific competition shape community composition at the scale of individual bird territories (~1-2 ha). Second, I use simulations of community assembly to show that trait-based metrics of community structure outperform phylogenetic metrics for detecting niche-based community assembly, and that both sets of metrics often have low power when multiple processes influence community composition. Third, taking a trait-based, species-level approach, I show that both habitat filtering and interspecific competition influence species occurrence at regional scales (~75000 km²), and interact with dispersal ability so that their effect on species occurrence is increased for species with greater dispersal ability. Finally, using a combination of trait- and isotope-based methods to quantify resource partitioning, I show that species' niche widths do not change and niche overlap is reduced at high compared to low species richness. Taken together, these results suggest that both habitat filtering and interspecific competition (i.e. niche-based processes) influence community assembly from local to regional scales. However, at least at regional scales, the degree to which these processes are important for determining the occurrence of any given species depends on that species's dispersal ability. They also suggest, based on niche-based interspecific competition influencing community composition, that differences in species richness among communities are in part explained by differences among sites in the breadth of available niche space, not by increased ecological specialisation or niche overlap.

Seasonality influences life history through its effect on the availability of essential resources, with birds timing breeding to occur during peak food availability. Due to density-dependence, investment in breeding is determined largely by the seasonality of food availability, with an increased investment being traded-off against adult survival. A bird's mass acts as an index of a species' foraging environment, because a bird bases its foraging decisions on a trade-off between the risk of predation and the risk of starvation. Under constant predation risk a bird increases its mass as insurance against increased foraging unpredictability. In tropical savannahs day length and temperature remains relatively constant, and there is not a season of increased density-dependent mortality which acts across all species. Thus species have evolved a broad range of life history traits under the same environmental conditions, although how a species experiences seasonality depends largely on its foraging niche. This thesis shows that most savannah species varied their mass across the year, having a reduced mass in the non-breeding season which suggests that foraging remained predictable. Independent of gonad or egg growth they then increased their mass as they started to breed, with the timing of breeding coinciding with peak food availability. Across species in the same foraging niche mass acts as an index of breeding investment, with females increasing their mass more than males. While across species in different foraging niches an increased mass response was associated with higher adult survival, probably because breeding strategy and subsequently adult survival are governed by food limitation. This thesis shows that birds adaptively manage their mass during breeding and that mass is not a result of energetic stress, thus under constant predation risk a bird's mass is a result of foraging predictability as a function of competition for available food and investment in breeding.