- About
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The Global ETD Search service is a free service for researchers
to find electronic theses and dissertations. This service is
provided by the
Networked Digital Library of Theses and Dissertations.
Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
Search results
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The role of PPAR-γ receptor agonists in mild asthmaAnderson, John Ross January 2014 (has links)
Asthma is complex and heterogeneous condition characterised by airway inflammation, airway hyperresponsiveness, variable airflow obstruction and symptoms including cough, wheeze and breathlessness. Many of those with asthma fail to achieve optimal control and there is a need to identify novel therapeutic targets and improve the way we detect airway inflammation if the burden of asthma is to be reduced. Chapters 1-4 explore whether agonists for the transcription factor, Peroxisome proliferator-activated receptor gamma (PPAR-y) have a role in asthma. We performed a single centre randomised two parallel group, double blind placebo controlled trial over a 12 week period using pioglitazone to activate PPAR-y. This was followed by a series of mechanistic in vitro experiments investigating whether there was evidence of PPAR-y translocation in sputum cells and airway smooth muscle cells.
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The domestic hygro-thermal environment, house dust mites and asthmaLawson, Alan January 2004 (has links)
No description available.
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Calcium influx mechanisms during mediator-induced responses in human airway smooth muscleMcVicker, Clare Geldard January 2003 (has links)
No description available.
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The differentiating and proliferative effects of transforming growth factor beta (TGFβ) and epidermal growth factor (EGF) on asthmatic fibroblastsBoxall, Christine Barbara January 2004 (has links)
No description available.
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Investigating the proteolytic function of A disintegrin and metalloproteinase 33 (ADAM33) and its role in asthma pathogenesisPang, Yun Yun January 2007 (has links)
No description available.
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Regulation of inflammatory responses in allergic asthmaCamporota, Luigi January 2006 (has links)
No description available.
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Exposure to indoor air pollution and the risk of upper and lower respiratory disease in asthmatic children and their mothersMatti, Salah January 2003 (has links)
No description available.
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Phenotype and functional properties of bronchoalveolar T cells from asthmatic and normal lungsBodey, Kathleen Jane January 2004 (has links)
No description available.
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Genetic and molecular characterisation of A Disintegrin and Metalloprotease (ADAM) 33Cakebread, Julie Ann January 2006 (has links)
No description available.
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Aeroallergens, air pollution and asthma morbidity : a time series analysisAtkinson, Richard William January 2006 (has links)
No description available.
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