The Laser Ablation of Microparticle Aerosols (LAMA) process produces nanoparticles by ablating microparticles that are entrained in an aerosol. Two of the main advantages of this process are that the particles produced are charged (preventing agglomeration) and bare (without a capping layer). Two different techniques are possible to collect the nanoparticles. In this work, the charged state of the particles formed was utilized to collect them electrostatically. This approach has the additional advantage that particles can be selected according to their size. The focus here was a particular application for gas separation. The nanoparticles produced were directly collected in a polymeric liquid, which was then irradiated with ultraviolet light to form a rubbery film. These membranes were tested for olefin/paraffin gas separation, a challenge that finds many applications, notably in the petroleum industry. / text

published_or_final_version / abstract / toc / Surgery / Doctoral / Doctor of Philosophy

published_or_final_version / Chemistry / Master / Master of Philosophy

Enhancing the effective peel resistance of plastically deforming adhesive joints through laser-based surface micro-machining Edwin Hernandez Diaz Inspired by adhesion examples commonly found in nature, we reached out to examine the effect of different kinds of heterogeneous surface properties that may replicate this behavior and the mechanisms at work. In order to do this, we used pulsed laser ablation on copper substrates (CuZn40) aiming to increase adhesion for bonding. A Yb-fiber laser was used for surface preparation of the substrates, which were probed with a Scanning Electron Microscope (SEM) and X-ray Photoelectron Spectroscopy (XPS). Heterogeneous surface properties were devised through the use of simplified laser micromachined patterns which may induce sequential events of crack arrest propagation, thereby having a leveraging effect on dissipation. The me- chanical performance of copper/epoxy joints with homogeneous and heterogeneous laser micromachined interfaces was then analyzed using the T-peel test. Fractured surfaces were analyzed using SEM to resolve the mechanism of failure and adhesive penetration within induced surface asperities from the treatment. Results confirm positive modifications of the surface morphology and chemistry from laser ablation that enable mechanical interlocking and cohesive failure within the adhesive layer. Remarkable improvements of apparent peel energy, bond toughness, and effective peel force were appreciated with respect to sanded substrates as control samples.

No description available.

Ablation and run-off on the White Glacier (38 km2), Axel Heiberg Island, N.W.T., were studied during the summers 1959-61 and some comparisons were made with nearby glaciers. Techniques of measuring ablation and run-off are described and assessed and the results of longterm, including full season, and short term measurements of both are presented. [...]

<p>This dissertation investigates the use of intraprocedure acoustic radiation force impulse (ARFI) imaging for visualization of radiofrequency ablation (RFA) lesions during cardiac transcatheter ablation (TCA) procedures. Tens of thousands of TCA procedures are performed annually to treat atrial fibrillation (AF) and other cardiac arrhythmias. Despite the use of sophisticated electroanatomical mapping (EAM) techniques to validate the modification of the electrical substrate, post-procedure arrhythmia recurrence is common due to incomplete lesion delivery and electrical conduction through lesion line discontinuities. The clinical demand for an imaging modality that can visually confirm the presence and completeness of RFA lesion lines motivated this research.</p><p>ARFI imaging is an ultrasound-based technique that transmits radiation force impulses to locally displace tissue and uses the tissue deformation response to generate images of relative tissue stiffness. RF-induced heating causes irreversible tissue necrosis and contractile protein denaturation that increases the stiffness of the ablated region. Preliminary in vitro and in vivo feasibility studies determined RF ablated myocardium appears stiffer in ARFI images.</p><p>This thesis describes results for ARFI imaging of RFA lesions for three research milestones: 1) an in vivo experimental verification model, 2) a clinically translative animal study, and 3) a preliminary clinical feasibility trial in human patients. In all studies, 2-D ARFI images were acquired in normal sinus rhythm and during diastole to maximize the stiffness contrast between the ablated and unablated myocardium and to minimize the bulk cardiac motion during the acquisition time.</p><p>The first in vivo experiment confirmed there was a significant decrease in the measured ARFI-induced displacement at ablation sites during and after focal RFA; the displacements in the lesion border zone and the detected lesion area stabilized over the first several minutes post-ablation. The implications of these results for ARFI imaging methods and the clinical relevance of the findings are discussed.</p><p>The second and third research chapters of this thesis describe the system integration and implementation of a multi-modality intracardiac ARFI imaging-EAM system for intraprocedure lesion evaluation. EAM was used to guide the 2-D ARFI imaging plane to targeted ablation sites in the canine right atrium (RA); the presence of EAM lesions markers and conduction disturbances in the local activation time (LAT) maps were used to find the sensitivity and specificity of predicting the presence of RFA lesion with ARFI imaging. The contrast and contrast-to-noise ratio between RFA lesion and unablated myocardium were calculated for ARFI and conventional ICE images. The opportunities and potential developments for clinical translation are discussed. </p><p>The last research chapter in this thesis describes a feasibility study of intracardiac ARFI imaging of RFA lesions in clinical patients. ARFI images of clinically relevant ablation sites were acquired, and this pilot study determined ARFI-induced displacements in human myocardium decreased at targeted ablation sites after RF-delivery. The challenges and successes of this pilot study are discussed.</p><p>This work provides evidence that intraprocedure ARFI imaging is a promising technology for the visualization of RFA lesions during cardiac TCA procedures. The clinical significance of this research is discussed, as well as challenges and considerations for future iterations of this technology aiming for clinical translation.</p> / Dissertation

Diamond is widely known for its extraordinary properties, such as high hardness, thermal conductivity, electron mobility, energy bandgap and durability making it a very attractive material for many applications. Synthetic diamonds retain most of the attractive properties of natural diamond. Among the types of synthetic diamonds, nanocrystalline diamond (NCD) is being developed for electrical, tribological, optical, and biomedical applications. In this research work, NCD films were grown by the pulsed electron beam ablation (PEBA) method at different process conditions such as accelerating voltage, pulse repetition rate, substrate material and temperature. PEBA is a relatively novel deposition technique, which has been developed to provide researchers with a new means of producing films of equal or better quality than more conventional methods such as Pulsed Laser Deposition, Sputtering, and Cathodic Vacuum Arc. The deposition process parameters have been defined by estimating the temperature and pressure of the plasma particles upon impact with the substrates, and comparing the data with the carbon phase diagram. Film thickness was measured by visible reflectance spectroscopy technique and was in the range of 40 – 230 nm. The nature of chemical bonding, namely, the ratio (sp3/sp3+sp2) and nanocrystallinity percentage were estimated using visible Raman spectroscopy technique. The films prepared from the ablation of a highly ordered pyrolytic graphite (HOPG) target on different substrates consisted mainly of nanocrystalline diamond material in association with a diamond-like carbon phase. The micro-structural properties and surface morphology of the films were studied by atomic force microscopy (AFM) and scanning electron microscopy (SEM). The mechanical properties of the NCD films were evaluated by nano-indentation.

No description available.

The term Gossamer is used to describe ultra-lightweight spacecraft structures that solve the aerospace challenge of obtaining maximum performance while reducing the launch costs of the spacecraft. Gossamer structures are extremely compliant, which complicates control design and ground testing in full scale. One approach is to design and construct smaller test articles and verify their computational models experimentally, so that similar computational models can be used to predict the dynamic performance of full-scale structures. Though measurement of both in-plane and out-of-plane displacements is required to characterize the dynamic response of the surface of these structures, this thesis lays the groundwork for dynamic measurement of the in-plane component. The measurement of thin films must be performed using non-contacting sensors because any contacting sensor would change the dynamics of the structure. Moreover, the thin films dealt with in this work are coated with either gold or aluminum for special applications making the film optically smooth and therefore requiring a surface pattern. A Krypton Fluoride excimer laser system was selected to fabricate patterns on thin-film mirror test articles. Parameters required for pattern fabrication were investigated. Effects of the pattern on the thin-film dynamics were studied using finite element analysis. Photogrammetry was used to study the static in-plane displacement of the thin-film mirror. This was performed to determine the feasibility of the photogrammetric approach for future dynamic tests. It was concluded that photogrammetry could be used efficiently to quantify dynamic in-plane displacement with high-resolution cameras and sub-pixel target marking.