Submitted by Jorge Silva (jorgelmsilva@ufrrj.br) on 2018-05-09T17:55:46Z No. of bitstreams: 1 2014 - Thiene Salazar Livio de Moraes.pdf: 2466223 bytes, checksum: 10b082d56f8727cf87f75df80791376b (MD5) / Made available in DSpace on 2018-05-09T17:55:46Z (GMT). No. of bitstreams: 1 2014 - Thiene Salazar Livio de Moraes.pdf: 2466223 bytes, checksum: 10b082d56f8727cf87f75df80791376b (MD5) Previous issue date: 2014-04-30 / Adjustment disorder is a diagnostic criterion associated with stress, which can occur during or after the occurrence of one or more stressful situations. It is a clinical condition which impairs the performance and social functioning and / or occupational functioning of the individual. However, it is noticed that the scientific studies on this topic are scarce. This master?s dissertation investigates the treatment kinds of Adjustment Disorder through a literature review and his prevalence among university students. Thus, this work is presented through two articles. The first is a systematic review of scientific literature of the articles about treatments for the Adjustment Disorder, published in the virtual library collections PsychInfo and PubMed / Medline. The result showed that, among the articles selected through some criteria, none is of Brazilian origin; all are from other countries, and most of the European continent. Therapies indicated in the studies were classified as psychotherapy, pharmacotherapy and herbal medicine. The second article focuses on the mental health of college students at the Universidade Federal Rural do Rio de Janeiro - Serop?dica. The study estimates the occurrence of the Adjustment Disorder among undergraduate students of the UFRRJ and detected the stressors preceding through a quantitative cross search, into a sample of 635 subjects. The results revealed that 19.4% of students matched the diagnostic criteria for the disorder Adaptation, according to the Inventory Valuation Adjustment Disorder (Self Report of the assessment of Adjustment Disorder) and 45.6 % showed susceptibility to development of psychopathological symptoms. Therefore, it is concluded that the mental health of the students in Brazilian universities, especially those that are located far from urban centers, requires scientific attention. Moreover, it is observed that little scientific attention has been given to Adjustment Disorder has collaborated that information on its prevalence in the general population and in specific populations as well as its diagnosis and its treatment remain scarce and inaccurate. / Transtorno de Adapta??o ? um crit?rio diagn?stico associado ao estresse, que pode se manifestar ap?s ou durante a ocorr?ncia de uma ou mais situa??es estressantes. ? um quadro cl?nico que entrava o desempenho e o funcionamento social e/ou ocupacional do indiv?duo. No entanto, percebe-se que os estudos cient?ficos sobre esse tema ainda s?o escassos. Esta disserta??o de mestrado se prop?s a investigar o Transtorno de Adapta??o a partir de uma revis?o de literatura, em torno dos tipos de tratamento e de sua preval?ncia entre estudantes universit?rios. Desse modo, esse trabalho ? apresentado atrav?s de dois artigos. O primeiro trata de uma revis?o sistem?tica da literatura cient?fica no que tange os artigos sobre tratamentos indicados para o Transtorno de Adapta??o, publicados nos acervos bibliogr?ficos virtuais Psycinfo e Pubmed/Medline. O resultado obtido mostrou que, dentre os artigos selecionados a partir dos crit?rios estabelecidos, nenhum ? de origem brasileira; todos s?o oriundos de outros pa?ses, sendo a maior parte do continente Europeu. As terapias indicadas nos estudos foram classificadas como Psicoterapia, Farmacoterapia e Fitoterapia. O segundo artigo enfoca a sa?de mental dos estudantes universit?rios da Universidade Federal Rural do Rio de Janeiro do campus Serop?dica. O trabalho estimou a ocorr?ncia do Transtorno de Adapta??o entre universit?rios da UFRRJ e detectou os fatores estressantes precedentes a ele, atrav?s de uma pesquisa Quantitativa Transversal, em uma amostra de 635 sujeitos. Os resultados revelaram que 19,4% dos alunos corresponderam aos crit?rios para o quadro de Transtorno de Adapta??o, segundo o Invent?rio de Avalia??o de Transtorno de Adapta??o (Self Report of the assessment of Adjustment disorder) e 45,6% demonstraram suscetibilidade ao desenvolvimento de sintomas psicopatol?gicos. Sendo assim, conclui-se que a sa?de mental dos graduandos das universidades brasileiras, principalmente naquelas que est?o localizadas distantes dos centros urbanos, requer aten??o do campo cient?fico. Al?m disso, observa-se que a pouca aten??o cient?fica dada ao Transtorno de Adapta??o tem corroborado para que informa??es sobre sua preval?ncia na popula??o geral e em popula??es espec?ficas, seu diagn?stico e seu tratamento continuem escassos e imprecisos.

Le blocage de la reconsolidation mnésique sous propranolol est utilisé pour traiter le trouble de stress post-traumatique (TSPT) et le trouble de l’adaptation (TA), montrant une réduction significative des symptômes auto-rapportés chez environ 70% des patients. La présente étude d’archive a examiné l’impact de la dose de propranolol sur l’efficacité de cette thérapie. Les données de quatre essais cliniques ont été regroupées. Un modèle mixte a été utilisé pour comparer les symptômes de stress entre deux groupes (dose de 1,67 mg/kg vs 1 mg/kg) sur la durée normale d’un traitement, soit 6 semaines. Les résultats ont indiqué que, comparativement au groupe (n = 61) ayant reçu la dose la plus élevée, celui (n = 76) ayant reçu une dose moins élevée a présenté une amélioration plus importante des symptômes à travers le temps, révélant ainsi un effet d'interaction, F(6, 740) = 8.54, p < .001. L’analyse secondaire examinant la corrélation dose-effet (dose absolue, p. ex., 40 mg, 50 mg, 60 mg, etc.) à travers les séances de traitement au sein de chacun des deux groupes n’a pas mis en lumière un effet de dose, ce qui était attendu. Des études prospectives seront nécessaires pour clarifier la relation dose-effet dans le cadre de cette thérapie. / Blocking memory reconsolidation with propranolol is used to treat post-traumatic stress disorder (PTSD) and adjustment disorder (AD), showing a significant reduction in self-reported symptoms in about 70% of patients. This archival study examined the impact of propranolol dosage on the efficacy of this therapy. Data from four clinical trials were pooled. Linear Mixed Model was used to compare stress symptoms between two groups (1.67 mg/kg vs. 1 mg/kg) over the typical 6-week treatment period. The results indicated that, compared to the group (n = 61) receiving the higher dosage, the group (n = 76) receiving the lower dosage showed a greater improvement in symptoms over time, revealing an interaction effect, F(6, 740) = 8.54, p < .001. A secondary analysis examining the dose-response correlation (absolute dose, e.g., 40 mg, 50 mg, 60 mg, etc.) over treatment sessions within each of the two groups did not reveal a dose effect, as expected. Prospective studies are needed to clarify the dose-response relationship in this therapy.

Text in English / This study was designed to determine whether a relationship exists between self-reported mindfulness, self-consciousness, adjustment and academic performance in first-year university students. Additionally, the study aimed to assess the predictive quality of mindfulness and self-consciousness towards emotional adjustment (adjustment disorder symptoms, depression and anxiety) and academic performance, and to further determine the contribution of mindfulness and self-consciousness on adjustment to the predictability of academic performance. First-year students (N = 290) at the Tshwane University of Technology (TUT) at the Pretoria West and Ga-Rankuwa campuses completed the selfreported mindfulness measure, Mindfulness Attention and Awareness Scale (MAAS) (Brown & Ryan, 2003), the Self Consciousness Scale- Revised (SCS-R) (Scheier & Carver, 1985), the Beck Depression Scale (BDI) (Beck et al., 1961) the Beck Anxiety Scale (BAI) Beck & Steer,1993) and the adjustment disorder checklist; based on DSM V, (Sadock, Sadock & Ruiz, 2014). Students’ year-end results for the first year of study were used to operationalize academic performance. Results of correlation analyses indicated a significant negative correlation between mindfulness and students’ emotional adjustment (adjustment disorder symptoms, depression and anxiety), a significant positive correlation between selfconsciousness and students’ emotional adjustment (adjustment disorder symptoms, depression and anxiety) as well as a significant negative correlation between adjustment disorder symptoms and academic performance. Multiple linear regression analysis was used to test whether mindfulness and self-consciousness significantly predicted students’ depression, anxiety and adjustment disorder symptoms. The results of the regression analysis indicated the two predictors explained 16% of the variance (F (1, 1773) = 29.66, P< 0.0001) (depression), 14% of the variance (F (1, 985) = 24.14, p < 0.0001) (anxiety) and 14% of variance (F (2, 292) = 23.87, p <0.001) (adjustment disorder symptoms). Furthermore, mediation analysis provided information regarding the impact of mindfulness and selfconsciousness on students’ academic performance. The impact of mindfulness and selfconsciousness on students’ academic performance (students’ marks) was found to be mediated by adjustment disorder symptoms. However, the Sobel test indicated a significant effect (0.03) for mindfulness and an insignificant effect (0.09) for self-consciousness. / Psychology / Ph. D. (Psychology)